Results 11 to 20 of about 48,775 (245)
Protocol for Ribosome Profiling in Bacteria [PDF]
Bio-Protocol, 2019 Ribosome profiling provides information on the position of ribosomes on mRNA on a genomic scale. Although this information is often used to detect changes in gene expression under different conditions, it also has great potential for yielding insight ...
Fuad Mohammad, Allen Buskirk
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riboWaltz: Optimization of ribosome P-site positioning in ribosome profiling data.
PLoS Computational Biology, 2018 Ribosome profiling is a powerful technique used to study translation at the genome-wide level, generating unique information concerning ribosome positions along RNAs.
Fabio Lauria +5 more
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Identification and analysis of ribosome-associated lncRNAs using ribosome profiling data [PDF]
BMC Genomics, 2018 Background Although the number of discovered long non-coding RNAs (lncRNAs) has increased dramatically, their biological roles have not been established.
Chao Zeng +2 more
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riboviz: analysis and visualization of ribosome profiling datasets [PDF]
BMC Bioinformatics, 2017 Background Using high-throughput sequencing to monitor translation in vivo, ribosome profiling can provide critical insights into the dynamics and regulation of protein synthesis in a cell.
Oana Carja +4 more
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Advances in ribosome profiling technologies. [PDF]
Biochem Soc TransRibosome profiling (or Ribo-seq) has emerged as a powerful approach for revealing the regulatory mechanisms of protein synthesis, on the basis of deep sequencing of ribosome footprints. Recent innovations in Ribo-seq technologies have significantly enhanced their sensitivity, specificity, and resolution.
Tomuro K, Iwasaki S.
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Identifying ribosome heterogeneity using ribosome profiling
Nucleic Acids Research, 2022 Abstract Recent studies have revealed multiple mechanisms that can lead to heterogeneity in ribosomal composition. This heterogeneity can lead to preferential translation of specific panels of mRNAs, and is defined in large part by the ribosomal protein (RP) content, amongst other things.
Ferhat Alkan +6 more
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Profiling of Mycoplasma gallisepticum Ribosomes [PDF]
Acta Naturae, 2015 The development of high-throughput technologies is increasingly resulting in identification of numerous cases of low correlation between mRNA and the protein level in cells. These controversial observations were made on various bacteria, such as E. coli, Desulfovibrio vulgaris, and Lactococcus lactis.
FISUNOV G.Y. +4 more
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Ribosome Profiling of Plants. [PDF]
Methods Mol Biol, 2023 Translation is a key step in control of gene expression, yet most analyses of global responses to a stimulus focus on transcription and the transcriptome. For RNA viruses in particular, which have no DNA-templated transcriptional control, control of viral and host translation is crucial.
Sonia J, Kanodia P, Lozier Z, Miller WA.
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Quantitative Modeling of Protein Synthesis Using Ribosome Profiling Data
Frontiers in Molecular Biosciences, 2021 Quantitative prediction on protein synthesis requires accurate translation initiation and codon translation rates. Ribosome profiling data, which provide steady-state distribution of relative ribosome occupancies along a transcript, can be used to ...
Vandana Yadav +3 more
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Ribonuclease selection for ribosome profiling [PDF]
Nucleic Acids Research, 2016 Ribosome profiling has emerged as a powerful method to assess global gene translation, but methodological and analytical challenges often lead to inconsistencies across labs and model organisms. A critical issue in ribosome profiling is nuclease treatment of ribosome-mRNA complexes, as it is important to ensure both stability of ribosomal particles and
Gerashchenko, Maxim, Gladyshev, Vadim
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