Results 11 to 20 of about 78,844 (296)
Active Ribosome Profiling with RiboLace [PDF]
Cell Reports, 2018 Summary: Ribosome profiling, or Ribo-seq, is based on large-scale sequencing of RNA fragments protected from nuclease digestion by ribosomes. Thanks to its unique ability to provide positional information about ribosomes flowing along transcripts, this ...
Massimiliano Clamer +15 more
doaj +8 more sources
Protocol for Ribosome Profiling in Bacteria [PDF]
Bio-Protocol, 2019 Ribosome profiling provides information on the position of ribosomes on mRNA on a genomic scale. Although this information is often used to detect changes in gene expression under different conditions, it also has great potential for yielding insight ...
Fuad Mohammad, Allen Buskirk
doaj +3 more sources
Ribosome profiling enhances understanding of mycobacterial translation
Frontiers in Microbiology, 2022 A recent addition to the -omics toolkit, ribosome profiling, enables researchers to gain insight into the process and regulation of translation by mapping fragments of mRNA protected from nuclease digestion by ribosome binding. In this review, we discuss
Elizabeth B. Sawyer, Teresa Cortes
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riboWaltz: Optimization of ribosome P-site positioning in ribosome profiling data. [PDF]
PLoS Computational Biology, 2018 Ribosome profiling is a powerful technique used to study translation at the genome-wide level, generating unique information concerning ribosome positions along RNAs.
Fabio Lauria +5 more
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Advances in ribosome profiling technologies. [PDF]
Biochem Soc TransRibosome profiling (or Ribo-seq) has emerged as a powerful approach for revealing the regulatory mechanisms of protein synthesis, on the basis of deep sequencing of ribosome footprints. Recent innovations in Ribo-seq technologies have significantly enhanced their sensitivity, specificity, and resolution.
Tomuro K, Iwasaki S.
europepmc +3 more sources
Identification and analysis of ribosome-associated lncRNAs using ribosome profiling data [PDF]
BMC Genomics, 2018 Background Although the number of discovered long non-coding RNAs (lncRNAs) has increased dramatically, their biological roles have not been established.
Chao Zeng +2 more
doaj +3 more sources
Identifying ribosome heterogeneity using ribosome profiling
Nucleic Acids Research, 2022 Abstract Recent studies have revealed multiple mechanisms that can lead to heterogeneity in ribosomal composition. This heterogeneity can lead to preferential translation of specific panels of mRNAs, and is defined in large part by the ribosomal protein (RP) content, amongst other things.
Ferhat Alkan +6 more
openaire +6 more sources
Ribosome Profiling of Plants. [PDF]
Methods Mol Biol, 2023 Translation is a key step in control of gene expression, yet most analyses of global responses to a stimulus focus on transcription and the transcriptome. For RNA viruses in particular, which have no DNA-templated transcriptional control, control of viral and host translation is crucial.
Sonia J, Kanodia P, Lozier Z, Miller WA.
europepmc +3 more sources
Profiling of Mycoplasma gallisepticum Ribosomes [PDF]
Acta Naturae, 2015 The development of high-throughput technologies is increasingly resulting in identification of numerous cases of low correlation between mRNA and the protein level in cells. These controversial observations were made on various bacteria, such as E. coli, Desulfovibrio vulgaris, and Lactococcus lactis.
FISUNOV G.Y. +4 more
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Bacterial riboproteogenomics : the era of N-terminal proteoform existence revealed [PDF]
, 2020 With the rapid increase in the number of sequenced prokaryotic genomes, relying on automated gene annotation became a necessity. Multiple lines of evidence, however, suggest that current bacterial genome annotations may contain inconsistencies and are ...
Fijalkowska, Daria +3 more
core +2 more sources