Results 71 to 80 of about 78,844 (296)

Domestic chickens activate a piRNA defense against avian leukosis virus [PDF]

, 2017
PIWI-interacting RNAs (piRNAs) protect the germ line by targeting transposable elements (TEs) through the base-pair complementarity. We do not know how piRNAs co-evolve with TEs in chickens.
Anai, Aravin, Aravin, Aravin, Assis, Baluda, Bao, Bartel, Benkel, Bolisetty, Boyce-Jacino, Boyce-Jacino, Brawand, Brennecke, Carmell, Cenik, Cenik, Chen, Chirn, Crittenden, Dempster, Eickbush, Eriksson, Fadly, Fagegaltier, Farazi, Feschotte, Flemr, Frisby, Frost, Gao, Ghildiyal, Gifford, Goic, Gunawardane, Guo, Haas, Han, Hayward, Houwing, Houwing, Ingolia, Ingolia, International Chicken Genome Sequencing Consortium, Johnson, Jurka, Ka, Ka, Khurana, Kim, Kohany, Kojima, Kuhnlein, Kumar, Kumar, Kuramochi-Miyagawa, Kuramochi-Miyagawa, Lee, Levin, Lewinski, Li, Li, Li, Lim, Lin, Lu, Malik, Malone, McClintock, Meunier, Moore, Nawrocki, Necsulea, Oh, Paradis, Peirson, Pelechano, Reuter, Reuter, Ricci, Roberts, Robinson, Rosenkranz, Rutherford, Sacco, Saxe, Schlötterer, Shoji, Smit, Smith, Smith, Smith, Smith, Soper, Stehelin, Steitz, Stoye, Sumiyoshi, Tam, Tanaka, Tarlinton, Team, Temin, Tereba, Thompson, Thomson, Trapnell, Trapnell, Vandergon, Varmus, Wang, Wang, Watanabe, Weiss, Weiss, Weiss, West, Wichert, Wicker, Wilson, Yabuta, Zhang, Zhang, Zheng, Zhuang   +124 more
core   +2 more sources

Transcriptome and translatome profiles of Streptomyces species in different growth phases. [PDF]

, 2020
Streptomyces are efficient producers of various bioactive compounds, which are mostly synthesized by their secondary metabolite biosynthetic gene clusters (smBGCs).
Cho, Byung-Kwan, Cho, Suhyung, Hwang, Soonkyu, Kim, Woori, Lee, Namil, Lee, Yongjae, Palsson, Bernhard   +6 more
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Microtubule-dependent ribosome localization in C. elegans neurons. [PDF]

, 2017
Subcellular localization of ribosomes defines the location and capacity for protein synthesis. Methods for in vivo visualizing ribosomes in multicellular organisms are desirable in mechanistic investigations of the cell biology of ribosome dynamics. Here,
Ellisman, Mark H, Goncharov, Alexandr, Jin, Yishi, Noma, Kentaro   +3 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Codon Resolution Analysis of Ribosome Profiling Data

, 2021
Translation is a central biological process in living cells. Ribosome profiling approach enables assessing translation on a global, cell-wide level. Extracting versatile information from the ribosome profiling data usually requires specialized expertise for handling the sequencing data that is not available to the broad community of experimentalists ...
Bartholomäus, A., Ignatova, Z.
openaire   +4 more sources

Ribosome profiling reveals translational regulation of mammalian cells in response to hypoxic stress

BMC Genomics, 2017
Background Retinal pigment epithelium (RPE) cells transfer oxygen and nutrients from choroid to the neural retina. Reduced oxygen to RPE perturbs development and functions of blood vessels in retina.
Zhiwen Jiang, Jiaqi Yang, Aimei Dai, Yuming Wang, Wei Li, Zhi Xie   +5 more
doaj   +1 more source

Optimization of carbon and energy utilization through differential translational efficiency. [PDF]

, 2018
Control of translation is vital to all species. Here we employ a multi-omics approach to decipher condition-dependent translational regulation in the model acetogen Clostridium ljungdahlii.
Al-Bassam, Mahmoud M, Gonzalez, David J, Kellman, Benjamin P, Kim, Ji-Nu, Wozniak, Jacob M, Zaramela, Livia S, Zengler, Karsten, Zuniga, Cristal   +7 more
core   +2 more sources

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

A systematically-revised ribosome profiling method for bacteria reveals pauses at single-codon resolution

eLife, 2019
In eukaryotes, ribosome profiling provides insight into the mechanism of protein synthesis at the codon level. In bacteria, however, the method has been more problematic and no consensus has emerged for how to best prepare profiling samples.
Fuad Mohammad, Rachel Green, Allen R Buskirk   +2 more
doaj   +1 more source