Results 1 to 10 of about 236,969 (404)

An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii

mBio, 2022
Antibiotic resistance among bacterial pathogens continues to pose a serious global health threat. Multidrug-resistant (MDR) strains of the Gram-negative organism Acinetobacter baumannii utilize a number of resistance determinants to evade current ...
Christopher E. Morgan, Zhemin Zhang, Robert A. Bonomo, Edward W. Yu   +3 more
doaj   +1 more source

RNA:protein ratio of the unicellular organism as a characteristic of phosphorous and nitrogen stoichiometry and of the cellular requirement of ribosomes for protein synthesis [PDF]

, 2006
Background Mean phosphorous:nitrogen (P:N) ratios and relationships of P:N ratios with the growth rate of organisms indicate a surprising similarity among and within microbial species, plants, and insect herbivores.
A Mehra, A Wada, AS Spirin, BJ Paul, C Condon, C Waldron, C Waldron, Carl E Sams, CH Williams, DE Larson, Duncan J Greenwood, EV Koonin, EV Koonin, FA Alberghina, GW Niven, H Bremer, H Bremer, J Bernhardt, JA Klappenbach, JF Martin, JF Martin, JJ Elser, JJ Elser, JJ Elser, John T Ammons, JT Auten, KW Boehlke, L Kerkhof, M Ehrenberg, M Ehrenberg, MR Knecht, R Mikkola, R Nieder, R Schmid, RA Cox, RG Westendorp, RJ Geider, RJ Lawrence, RO Poyton, RW Mink, RW Shulman, RW Sterner, S Gusewell, S Jonasson, T Moss, T Nyström, Tatiana V Karpinets, TM Walker, WM El-Sharoud   +48 more
core   +4 more sources

Specialized ribosomes and specific ribosomal protein paralogs control translation of mitochondrial proteins

Journal of Cell Biology, 2018
Genome duplication in eukaryotes created paralog pairs of ribosomal proteins (RPs) that show high sequence similarity/identity. However, individual paralogs can confer vastly different effects upon cellular processes, e.g., specific yeast paralogs ...
N. Segev, J. Gerst
semanticscholar   +1 more source

The PDB and the ribosome [PDF]

Journal of Biological Chemistry, 2021
This essay, which was written to commemorate the 50th anniversary of the Protein Data Bank, opens with some comments about the intentions of the scientists who pressed for its establishment and the nature of services it provides. It includes a brief account of the events that resulted in the determination of the crystal structure of the large ribosomal
openaire   +3 more sources

The metabolism of aged seeds. The free and membrane-bound polyribosomes of germinating rye grains of different ages

Acta Societatis Botanicorum Poloniae, 2014
Grains of winter rye harvested in 1976, 1978, 1982 and 1984 were studied. Free and membrane-bound polyribosomes were isolated from embryos of imbibing and germinating grains.
Kazimierz Zalewski
doaj   +1 more source

Characterization of Factors Involved in Localized Translation Near Mitochondria by Ribosome-Proximity Labeling

Frontiers in Cell and Developmental Biology, 2019
Mitochondria exert their many functions through a repertoire of hundreds of proteins. The vast majority of these proteins are encoded in the nuclear genome, translated in the cytosol and imported into the mitochondria. Current models, derived mainly from
Dikla Vardi-Oknin, Dikla Vardi-Oknin, Yoav Arava   +2 more
doaj   +1 more source

Extensive evolution of cereal ribosome-inactivating proteins translates into unique structural features, activation mechanisms, and physiological roles [PDF]

, 2017
Ribosome-inactivating proteins (RIPs) are a class of cytotoxic enzymes that can depurinate rRNAs thereby inhibiting protein translation. Although these proteins have also been detected in bacteria, fungi, and even some insects, they are especially ...
De Zaeytijd, Jeroen, Van Damme, Els
core   +2 more sources

How Ribosomes Translate Cancer.

Cancer Discovery, 2017
A wealth of novel findings, including congenital ribosomal mutations in ribosomopathies and somatic ribosomal mutations in various cancers, have significantly increased our understanding of the relevance of ribosomes in oncogenesis.
Sergey O. Sulima, I. Hofman, K. De Keersmaecker, J. Dinman   +3 more
semanticscholar   +1 more source

A limited concentration range of diaphorin, a polyketide produced by a bacterial symbiont of the Asian citrus psyllid, promotes the in vitro gene expression with bacterial ribosomes

Microbiology Spectrum
Diaphorin is a polyketide produced by “Candidatus Profftella armatura” (Gammaproteobacteria: Burkholderiales), an obligate symbiont of a devastating agricultural pest, the Asian citrus psyllid Diaphorina citri (Hemiptera: Psyllidae).
Rena Takasu, Takashi Izu, Atsushi Nakabachi   +2 more
doaj   +1 more source

The influence of exogenous spermidine on polysomes and RNase activity in wheat leaves under water stress conditions short communication

Acta Societatis Botanicorum Poloniae, 2014
It was found that spermidine (5mM) delivered to wheat seedlings through their roots prior to water stress affected the state of polysomes and ribosomes under water stress conditions, which was manifested in stabilization of 80 S ribosomes and in ...
Halina Gniazdowska-Skoczek, Zenon Krzywański, Jan Kubiś   +2 more
doaj   +1 more source