Results 1 to 10 of about 110,864 (168)
Identifying ribosome heterogeneity using ribosome profiling
Nucleic Acids Research, 2022 Abstract Recent studies have revealed multiple mechanisms that can lead to heterogeneity in ribosomal composition. This heterogeneity can lead to preferential translation of specific panels of mRNAs, and is defined in large part by the ribosomal protein (RP) content, amongst other things.
Ferhat Alkan +6 more
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Cell, 2001 The conversion of a ribosomal RNA transcript to a cytoplasmic ribosome requires hundreds of accessory RNA and protein factors. Two papers published recently in Molecular Cell provide first looks at the association of these processing factors with the intermediates in ribosome synthesis (Harnpicharnchai et al., 2001; Bassler et al., 2001).
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Ribosomal proteins: functions beyond the ribosome [PDF]
Journal of Molecular Cell Biology, 2015 Although ribosomal proteins are known for playing an essential role in ribosome assembly and protein translation, their ribosome-independent functions have also been greatly appreciated. Over the past decade, more than a dozen of ribosomal proteins have been found to activate the tumor suppressor p53 pathway in response to ribosomal stress. In addition,
Xiang, Zhou +4 more
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Ribosome-omics of the human ribosome [PDF]
RNA, 2014 The torrent of RNA-seq data becoming available not only furnishes an overview of the entire transcriptome but also provides tools to focus on specific areas of interest. Our focus on the synthesis of ribosomes asked whether the abundance of mRNAs encoding ribosomal proteins (RPs) matched the equimolar need for the RPs in the assembly of ribosomes.
Gupta, Varun, Warner, Jonathan R.
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Ribosomal Proteins in Ribosome Assembly
BiomoleculesRibosomes are the cellular machinery responsible for translating mRNA into proteins, a process fundamental to all domains of life from bacteria to eukaryotes [...]
Brigitte Pertschy, Ingrid Zierler
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Ribosomes, Ribosomal Subunits and Ribosomal Proteins from Myxococcus xanthus [PDF]
Journal of General Microbiology, 1973 SUMMARY: Polyribosomes and ribosomes were isolated from vegetative Myxococcus xanthus FB and myxospores. The sedimentation coefficients of monoribosomes and ribosomal subunits were the same as those for equivalent particles from Escherichia coli. Conditions for the dissociation of the ribosomes and the unfolding of the subunits (in strong salt or very ...
H. A. FOSTER, J. H. PARISH
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Orchestrating ribosomal RNA folding during ribosome assembly
BioEssays, 2022 AbstractConstruction of the eukaryotic ribosome is a complex process in which a nascent ribosomal RNA (rRNA) emerging from RNA Polymerase I hierarchically folds into a native three‐dimensional structure. Modular assembly of individual RNA domains through interactions with ribosomal proteins and a myriad of assembly factors permit efficient ...
Oborská-Oplová, Michaela +2 more
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Mass spectrometry of ribosomes and ribosomal subunits [PDF]
Proceedings of the National Academy of Sciences, 1998 Nanoflow electrospray ionization has been used to introduce intact Escherichia coli ribosomes into the ion source of a mass spectrometer. Mass spectra of remarkable quality result from a partial, but selective, dissociation of the particles within the mass spectrometer.
Benjamin, DR +4 more
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Sleeping Beauty redux – resting ribosomes in neurons [PDF]
, 2022 Sarah Loerch +3 more
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Ribosomes in platelets protect the messenger [PDF]
, 2017 Jesse W. Rowley, Andrew S. Weyrich
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