Results 1 to 10 of about 184,743 (340)

Molecular Mimicry of SecA and Signal Recognition Particle Binding to the Bacterial Ribosome

mBio, 2019
Bacteria execute a variety of protein transport systems for maintaining the proper composition of their different cellular compartments. The SecYEG translocon serves as primary transport channel and is engaged in transporting two different substrate ...
Lara Knüpffer, Clara Fehrenbach, Kärt Denks, Veronika Erichsen, Narcis-Adrian Petriman, Hans-Georg Koch   +5 more
doaj   +1 more source

Adaptation of Translational Machinery in Malaria Parasites to Accommodate Translation of Poly-Adenosine Stretches Throughout Its Life Cycle

Frontiers in Microbiology, 2019
Malaria is caused by unicellular apicomplexan parasites of the genus Plasmodium, which includes the major human parasite Plasmodium falciparum. The complex cycle of the malaria parasite in both mosquito and human hosts has been studied extensively. There
Jessey Erath, Sergej Djuranovic, Slavica Pavlovic Djuranovic   +2 more
doaj   +1 more source

The Stringent Response Inhibits 70S Ribosome Formation in Staphylococcus aureus by Impeding GTPase-Ribosome Interactions

mBio, 2021
During nutrient limitation, bacteria produce the alarmones (p)ppGpp as effectors of a stress signaling network termed the stringent response. RsgA, RbgA, Era, and HflX are four ribosome-associated GTPases (RA-GTPases) that bind to (p)ppGpp in ...
Daniel J. Bennison, Jose A. Nakamoto, Timothy D. Craggs, Pohl Milón, John B. Rafferty, Rebecca M. Corrigan   +5 more
doaj   +1 more source

Ribosome Inactivating Protein of barley enhanced resistance to Rhizoctonia solani in transgenic potato cultivar 'Desirée' in greenhouse conditions

Biotechnologie, Agronomie, Société et Environnement, 2013
In the present study, the potato cultivar 'Desirée' was transformed via Agrobacterium tumefaciens strain LBA4404 containing the plasmid pBIN19 which harbors the Ribosome Inactivating Protein (rip30).
M'hamdi, M., Chikh-Rouhou, H., Boughalleb, N., Ruiz de Galarreta, JI.   +3 more
doaj  

Identification and characterization of yeast SNF1 kinase homologs in Leishmania major

Frontiers in Molecular Biosciences
BackgroundSucrose Non Fermenting1 (SNF1) constitutes a family of protein kinases conserved in eukaryotes, plants, and fungi. SNF1 has been known to play a crucial role in stress adaptation and metabolism, enabling organisms to respond to changing ...
Gaurav Shoeran, Namrata Anand, Upninder Kaur, Kapil Goyal, Rakesh Sehgal   +4 more
doaj   +1 more source

The metabolism of aged seeds. The free and membrane-bound polyribosomes of germinating rye grains of different ages

Acta Societatis Botanicorum Poloniae, 2014
Grains of winter rye harvested in 1976, 1978, 1982 and 1984 were studied. Free and membrane-bound polyribosomes were isolated from embryos of imbibing and germinating grains.
Kazimierz Zalewski
doaj   +1 more source

A limited concentration range of diaphorin, a polyketide produced by a bacterial symbiont of the Asian citrus psyllid, promotes the in vitro gene expression with bacterial ribosomes

Microbiology Spectrum
Diaphorin is a polyketide produced by “Candidatus Profftella armatura” (Gammaproteobacteria: Burkholderiales), an obligate symbiont of a devastating agricultural pest, the Asian citrus psyllid Diaphorina citri (Hemiptera: Psyllidae).
Rena Takasu, Takashi Izu, Atsushi Nakabachi   +2 more
doaj   +1 more source

How Cancer Exploits Ribosomal RNA Biogenesis: A Journey beyond the Boundaries of rRNA Transcription

Cells, 2019
The generation of new ribosomes is a coordinated process essential to sustain cell growth. As such, it is tightly regulated according to cell needs. As cancer cells require intense protein translation to ensure their enhanced growth rate, they exploit ...
Marco Gaviraghi, Claudia Vivori, Giovanni Tonon   +2 more
doaj   +1 more source

The Arabidopsis cytosolic ribosomal proteome: from form to function

Frontiers in Plant Science, 2013
The cytosolic ribosomal proteome of Arabidopsis thaliana has been studied intensively by a range of proteomics approaches and is now one of the best-characterised eukaryotic ribosomal proteomes.
Adam James Carroll
doaj   +1 more source

Accelerating cancer without mutations

eLife, 2019
Mice get melanoma faster when they have common, inherited variants in a few genes that control cell-wide changes but also respond to the environment.
Douglas E Brash
doaj   +1 more source