Results 131 to 140 of about 105,196 (322)
Notizen: Effect of X-radiation on the Ribosomes of Yeast Cells [PDF]
, 1968 Nandini Ghosh
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Advanced Science, EarlyView.In this study, it is proposed that SENP3 accumulates in macrophages of aneurysmal aortic tissues, which promotes macrophage ferroptosis and inflammation via regulation of CTH de‐SUMOylation. Abstract Abdominal aortic aneurysm (AAA) is a high‐risk inflammatory disorder. SENP3, a SUMO2/3‐specific protease, is closely involved in the development of cancer.
Long Chen +15 more
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Lincomycin, an inhibitor of aminoacyl sRNA binding to ribosomes. [PDF]
, 1966 F.N. Chang +2 more
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Mitofusin 1 Drives Preimplantation Development by Enhancing Chromatin Incorporation of Histone H3.3
Advanced Science, EarlyView.MFN1 exerts its function partially through histone H3.3 in early embryos. MFN1 colocalizes with PADI6, and its deficiency results in compromised cytoplasmic lattices and ribosomal subunits, leading to declined H3.3 protein level. This, in turn, hinders the incorporation of H3.3 into the embryonic genome, thereby causing failure of male pronucleus ...
Xiao‐yan Shi +9 more
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Ribosomal proteins and the assembly of ribosomes in eukaryotes [PDF]
Biochemical Journal, 1972 J R Warner, S A Udem, A Kumar, R S Wu
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RAB3B Dictates mTORC1/S6 Signaling in Chordoma and Predicts Response to mTORC1‐Targeted Therapy
Advanced Science, EarlyView.RAB3B is unveiled as a prominent oncogenic regulator in chordoma, which can block the DUSP12‐mediated dephosphorylation of p‐S6 (S235/236). The combination of RAB3B and p‐S6 indicates a good prognostic value and predicts mTORC1 inhibitors response for chordoma patients.
Jianxuan Gao +15 more
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Role of eIF4A1 in triple‐negative breast cancer stem‐like cell‐mediated drug resistance
Cancer Reports, Volume 5, Issue 12, December 2022., 2022 Abstract In cap‐dependent translation, the eukaryotic translation initiation factor 4A (eIF4A1) is an mRNA helicase is involved in unwinding of the secondary structure, such as the stem‐loops, at the 5′‐leader regions of the key oncogenic mRNAs. This facilitates ribosomal scanning and translation of the oncogenic mRNAs.
Dayanidhi Raman, Amit K. Tiwari
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Studies on the formation of trensfer ribonucleic acid-ribosome complexes. V. On the function of a soluble transfer factor in protein synthesis. [PDF]
, 1968 Sidney Pestka
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Advanced Science, EarlyView.Inspired by exercise‐induced metabolic rewiring and EV secretion, this study shows that in vivo metabolic engineering strategy can reprogram EV secretion pattern and simultaneously attenuate multiple tissue injury in CKD status, highlighting that it is a potential strategy for treating diverse chronic diseases.
Meng Zhao +11 more
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ELECTROPHORESIS, Volume 43, Issue 23-24, Page 2402-2427, December 2022., 2022 Abstract Nucleic acids are the blueprint of life. They are not only the construction plan of the single cell or higher associations of them, but also necessary for function, communication and regulation. Due to the pandemic, the attention shifted in particular to their therapeutic potential as a vaccine. As pharmaceutical oligonucleotides are unique in
Robert Minkner +3 more
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