Results 151 to 160 of about 104,929 (312)
Advanced Science, EarlyView.A bismuth–copper diselenide–based nanoplatform (BSCS@PHY) coordinates immunogenic cell death with local A2A receptor blockade in 4T1 tumors. Thermally triggered shell melting exposes catalytic surfaces for glutathione depletion and chemodynamic ROS generation, while co‐delivering an A2AR antagonist and yeast‐wall adjuvant to enhance dendritic‐cell ...
Xiangting Yi +12 more
wiley +1 more source
Properties of 70S and 80S ribosomes from tobacco leaves
, 1970 1. The interaction of exogenous messengers with 70 S chloroplast and 80 S cytoplasmic tobacco ribosomes in vitro was studied. The isolation of an amino acid incorporating system from tobacco leaves should enable us to study some aspects of viral protein ...
Brouwer, D.
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Advanced Science, EarlyView.Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu +9 more
wiley +1 more source
Crystal structures of naturally inhibited ribosomes
, 2011 Ribosomes are complex macromolecular machines that translate the genetic code. Over the past decade, numerous insights into the process of translation have been gained through structural studies of ribosomes using x-ray crystallography.
Pearson, Michael D.
core
Orthogonal Protein Synthesis by Ribosomes with an Integrated mRNA
Ribosomes drive protein synthesis by translating the mRNA into the amino acid sequence of proteins. Given the importance of proteins and peptides, many efforts have focused on engineering the ribosome to expand its functionality beyond its repertoire of ...
Kasra Alizadeh (23292040)
core +1 more source
Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration
Advanced Science, EarlyView.This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya +10 more
wiley +1 more source
Studies on structural stability of thermophilic Sulfolobus acidocaldarius ribosomes
, 2007 19-25Structural stability of thermophilic archaeon Sulfolobus acidocaldarius ribosomes, with respect their susceptibility to pancreatic RNase A and stability to temperature (ΔTm), on treatment with various stabilizing (polyamines) and destabilizing ...
Suryanarayana, Tangirala +1 more
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Advanced Science, EarlyView.A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li +13 more
wiley +1 more source
Ribosomes of Acetabularia mediterranea
, 1969 1. 1. Whole homogenates of [3H]uridine-labelled Acetabularia mediterranea contain two major species of radioactive ribosomal particles, sedimenting at approx. 50 and 30 S. These particles contain, respectively, high and low molecular weight ribosomal RNA
Presburg, Monique +2 more
core
Angewandte Chemie, EarlyView.Rationally designed DNA multivalent aptamers direct specific protein binding to drive self‐assembly into protein‐DNA frameworks (PDFs). Structurally defined protein‐aptamer interfaces organize proteins into triangles, linear and ladderlike chains, and periodic two‐dimensional arrays, enabling precise control over orientation, connectivity, and overall ...
Zhe Zhang +11 more
wiley +2 more sources