Results 61 to 70 of about 181,355 (258)

Modelling the effect of ribosome mobility on the rate of protein synthesis [PDF]

open access: yesEur. Phys. J. E 44, 19 (2021), 2020
Translation is one of the main steps in the synthesis of proteins. It consists of ribosomes that translate sequences of nucleotides encoded on mRNA into polypeptide sequences of amino acids. Ribosomes bound to mRNA move unidirectionally, while unbound ribosomes diffuse in the cytoplasm.
arxiv   +1 more source

Characterization of Factors Involved in Localized Translation Near Mitochondria by Ribosome-Proximity Labeling

open access: yesFrontiers in Cell and Developmental Biology, 2019
Mitochondria exert their many functions through a repertoire of hundreds of proteins. The vast majority of these proteins are encoded in the nuclear genome, translated in the cytosol and imported into the mitochondria. Current models, derived mainly from
Dikla Vardi-Oknin   +2 more
doaj   +1 more source

The Stringent Response Inhibits 70S Ribosome Formation in Staphylococcus aureus by Impeding GTPase-Ribosome Interactions

open access: yesmBio, 2021
During nutrient limitation, bacteria produce the alarmones (p)ppGpp as effectors of a stress signaling network termed the stringent response. RsgA, RbgA, Era, and HflX are four ribosome-associated GTPases (RA-GTPases) that bind to (p)ppGpp in ...
Daniel J. Bennison   +5 more
doaj   +1 more source

Traffic of interacting ribosomes: effects of single-machine mechano-chemistry on protein synthesis [PDF]

open access: yesPhysical Review E 75, 021902 (2007), 2006
Many ribosomes simultaneously move on the same messenger RNA (mRNA), each separately synthesizing the protein coded by the mRNA. Earlier models of ribosome traffic represent each ribosome by a ``self-propelled particle'' and capture the dynamics by an extension of the totally asymmetric simple exclusion process (TASEP).
arxiv   +2 more sources

The influence of exogenous spermidine on polysomes and RNase activity in wheat leaves under water stress conditions short communication

open access: yesActa Societatis Botanicorum Poloniae, 2014
It was found that spermidine (5mM) delivered to wheat seedlings through their roots prior to water stress affected the state of polysomes and ribosomes under water stress conditions, which was manifested in stabilization of 80 S ribosomes and in ...
Halina Gniazdowska-Skoczek   +2 more
doaj   +1 more source

Nascent Ribosomes [PDF]

open access: yesCell, 2001
The conversion of a ribosomal RNA transcript to a cytoplasmic ribosome requires hundreds of accessory RNA and protein factors. Two papers published recently in Molecular Cell provide first looks at the association of these processing factors with the intermediates in ribosome synthesis (Harnpicharnchai et al., 2001; Bassler et al., 2001).
openaire   +2 more sources

The metabolism of aged seeds. The free and membrane-bound polyribosomes of germinating rye grains of different ages

open access: yesActa Societatis Botanicorum Poloniae, 2014
Grains of winter rye harvested in 1976, 1978, 1982 and 1984 were studied. Free and membrane-bound polyribosomes were isolated from embryos of imbibing and germinating grains.
Kazimierz Zalewski
doaj   +1 more source

The mitochondrial ribosome from Locusta migratoria [PDF]

open access: yes, 1971
Mitochondrial ribosomes from locust thorax muscles have been identified recently in our labo-ratory by specific labelling of the adhering nascent peptide chains and have been isolated from ...
Ashwell   +19 more
core   +1 more source

Bacterial Longevity Requires Protein Synthesis and a Stringent Response

open access: yesmBio, 2019
Gram-negative bacteria in infections, biofilms, and industrial settings often stop growing due to nutrient depletion, immune responses, or environmental stresses.
Liang Yin   +5 more
doaj   +1 more source

An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii

open access: yesmBio, 2022
Antibiotic resistance among bacterial pathogens continues to pose a serious global health threat. Multidrug-resistant (MDR) strains of the Gram-negative organism Acinetobacter baumannii utilize a number of resistance determinants to evade current ...
Christopher E. Morgan   +3 more
doaj   +1 more source

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