Results 71 to 80 of about 104,929 (312)
Translating the Game: Ribosomes as Active Players [PDF]
, 2018 Ribosomes have been long considered as executors of the translational program. The fact that ribosomes can control the translation of specific mRNAs or entire cellular programs is often neglected.
Stefano Biffo +9 more
core +3 more sources
Bacterial Longevity Requires Protein Synthesis and a Stringent Response
mBio, 2019 Gram-negative bacteria in infections, biofilms, and industrial settings often stop growing due to nutrient depletion, immune responses, or environmental stresses.
Liang Yin +5 more
doaj +1 more source
Biotechnology Journal, 2012 AbstractSee accompanying article by Contreras‐Martin et al.
openaire +2 more sources
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
, 2014 Ribosomes are fundamental components of the cell that are essential for its growth and proliferation. It is hard to imagine that such a fundamental physiological machinery, as ribosomes, does not participate in cancer biology.
Sara Ricciardi +3 more
core +1 more source
Mass spectrometry of intact ribosomes
, 2005 The ability to maintain intact ribosomes in the mass spectrometer has enabled research into their changes in conformation and interactions. In the mass spectrometer, it is possible to induce dissociation of proteins from the intact ribosome and, in ...
Videler, Hortense +4 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam +8 more
wiley +1 more source
Pathways to Specialized Ribosomes: The Brussels Lecture
, 2016 “Specialized ribosomes” is a topic of intense debate and research whose provenance can be traced to the earliest days of molecular biology. Here, the history of this idea is reviewed, and critical literature in which the specialized ribosomes have come ...
Dinman, Jonathan D.
core +1 more source
Biotechnologie, Agronomie, Société et Environnement, 2013 In the present study, the potato cultivar 'Desirée' was transformed via Agrobacterium tumefaciens strain LBA4404 containing the plasmid pBIN19 which harbors the Ribosome Inactivating Protein (rip30).
M'hamdi, M. +3 more
doaj