Results 101 to 110 of about 44,034 (296)

Capturing the essence of folding and functions of biomolecules using Coarse-Grained Models

, 2011
The distances over which biological molecules and their complexes can function range from a few nanometres, in the case of folded structures, to millimetres, for example during chromosome organization. Describing phenomena that cover such diverse length,
A Dhar, A Elcock, A Elcock, A Grosberg, A Grosberg, A Minton, A Pisliakov, A Podtelezhnikov, A Rychkova, A Savelyev, A Vologodskii, AA Podtelezhnikov, B Messer, BJ Alder, C Bustamante, C Clementi, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, D Thirumalai, D Thirumalai, D Thirumalai, D Thirumalai, D Thirumalai, E Koculi, E Lieberman-Aiden, E O'Brien, E Shakhnovich, EP O'Brien, F Valle, G Lorimer, G Papoian, G Ziv, H Liu, H Ma, HX Zhou, I Tinoco Jr., J Chen, J Harms, J Karanicolas, J Straub, JD Honeycutt, JM Fernandez, JN Onuchic, KA Dill, M Levitt, M Mickler, M Strajbl, M Takano, ME Fisher, MJ Todd, MS Cheung, N Hirokawa, N Koga, N Toan, OK Dudko, P Weinkam, PB Moore, PC Whitford, Q Du, R Russell, R Tehver, R Tehver, RD Vale, RD Vale, RI Dima, RW Pastor, S Jun, S Jun, S Jun, S Kamerlin, S Kirkpatrick, S Moghaddam, SB Smith, SJ Chen, SJ Marrink, T Cloutier, T Cremer, T Kirkpatrick, T Veitshans, V Lubchenko, Z Liu, Z Xu   +89 more
core   +1 more source

High‐Efficiency Genome Editing of Chlorella sp. by CRISPR/Cas9

Plant Biotechnology Journal, EarlyView.
Xinyu Cui, Yi Xin, Yuan Xiao, Bixin Zhang, Qinhua Gan, Yandu Lu   +5 more
wiley   +1 more source

Probiotic‐Based Materials as Living Therapeutics

Advanced Materials, Volume 38, Issue 1, 2 January 2026.
Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio, Graham J. Day, Manuel Salmeron‐Sanchez   +2 more
wiley   +1 more source

Lipid vesicles chaperone an encapsulated RNA aptamer. [PDF]

, 2018
The organization of molecules into cells is believed to have been critical for the emergence of living systems. Early protocells likely consisted of RNA functioning inside vesicles made of simple lipids.
Chen, Irene A, Saha, Ranajay, Verbanic, Samuel   +2 more
core   +1 more source

Discovery of Viroids and Viroid‐Like RNAs in Plants

Plant Biotechnology Journal, EarlyView.
Zhiyou Xuan, Fei Xing, Xinying Yang, Qingsong Wang, Xiaoru Wang, Song Zhang, Xuedong Liu, Hongbo Jiang, Zongtao Sun, Fang Ren, Shuai Li, Feng Ding, Shifang Li, Changyong Zhou, Zhixiang Zhang, Mengji Cao   +15 more
wiley   +1 more source

Payload‐Driven Design of Polymeric Carriers for Nucleic Acid Delivery: Insights from Structure–Function Relationships

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Polymeric carriers provide versatile platforms for nucleic acid delivery. This review introduces a novel perspective inspired by protein structural organization to explore structure–function relationships of polymeric carriers, highlighting requirements of different nucleic acid payloads.
Hanieh Moradian, Charlotte Maeve Dunne, Manfred Gossen, Matthias Hartlieb   +3 more
wiley   +1 more source

The structure and catalytic mechanism of a pseudoknot-containing hammerhead ribozyme

Nature Communications
We have determined the crystal structure of a pseudoknot (PK)-containing hammerhead ribozyme that closely resembles the pistol ribozyme, with essentially identical secondary structure and connectivity. The activity is more sensitive to deletion of the G8
Xuelin Zhan, Timothy J. Wilson, Zhenzhen Li, Jingjing Zhang, Yili Yang, David M. J. Lilley, Yijin Liu   +6 more
doaj   +1 more source

Phylogeny of conserved adenines in linkers of Group-I introns [PDF]

, 2009
We have analyzed the linkers in group-I introns, a characteristic region that is crucial to the folding and splicing process of the folded RNA, in seventy sequences spreading across r-RNA, t-RNA and organelle genes from various organisms including algae,
Chandrasekhar Kesavan, Natarajan Ganesan
core   +1 more source

Large Phenotypic Enhancement of Structured Random RNA Pools. [PDF]

, 2020
Laboratory evolution of functional RNAs has applications in many areas of chemical and synthetic biology. In vitro selections critically depend on the presence of functional molecules, such as aptamers and ribozymes, in the starting sequence pools.
Chizzolini, Fabio, Dingilian, Armine I, Lupták, Andrej, Oumais, Mona, Passalacqua, Luiz FM, Szostak, Jack W   +5 more
core  

Prediction and statistics of pseudoknots in RNA structures using exactly clustered stochastic simulations

, 2003
Ab initio RNA secondary structure predictions have long dismissed helices interior to loops, so-called pseudoknots, despite their structural importance.
A. Xayaphoummine, Evers, F. Thalmann, Ferr  -D'Amar  , Giedroc, Gultyaev, H. Isambert, Higgs, Lehnert, Mathews, McCaskill, Mironov, Pan, Pleij, Rivas, Russell, Sclavi, Shirts, T. Bucher, Tinoco, Treiber, Zarrinkar, Zuker   +22 more
core   +3 more sources