Results 131 to 140 of about 28,198 (287)
A ribozyme that triphosphorylates RNA 5′-hydroxyl groups
Nucleic Acids Research, 2014 The RNA world hypothesis describes a stage in the early evolution of life in which RNA served as genome and as the only genome-encoded catalyst. To test whether RNA world organisms could have used cyclic trimetaphosphate as an energy source, we developed
J. Moretti, U. F. Müller
semanticscholar +1 more source
CHIMIA, 2018 Ribonuclease P (RNase P) is a class of enzymes involved in the processing of precursor tRNAs to remove their 5'-leader sequences. Ribonuclease P enzymes are classified into two completely distinct classes, i.e.
Yuri Nozawa +3 more
doaj +1 more source
Ribozyme-mediated attenuation of pancreatic beta-cell glucokinase expression in transgenic mice results in impaired glucose-induced insulin secretion. [PDF]
, 1994 Shimon Efrat +9 more
openalex +1 more source
New tools provide a second look at HDV ribozyme structure, dynamics and cleavage
Nucleic Acids Research, 2014 The hepatitis delta virus (HDV) ribozyme is a self-cleaving RNA enzyme essential for processing viral transcripts during rolling circle viral replication.
Gary J. Kapral +5 more
semanticscholar +1 more source
Ripping RNA by Force using Gaussian Network Models [PDF]
J. Phys. Chem. B (2017) vol. 121, 3515-3522, 2016 Using force as a probe to map the folding landscapes of RNA molecules has become a reality thanks to major advances in single molecule pulling experiments. Although the unfolding pathways under tension are complicated to predict studies in the context of proteins have shown that topology plays is the major determinant of the unfolding landscapes.
arxiv
Can hammerhead ribozymes be efficient tools to inactivate gene function? [PDF]
, 1994 Édouard Bertrand +2 more
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Autocatalytic Sets and RNA Secondary Structure [PDF]
arXiv, 2016 The dominant paradigm in origin of life research is that of an RNA world. However, despite experimental progress towards the spontaneous formation of RNA, the RNA world hypothesis still has its problems. Here, we introduce a novel computational model of chemical reaction networks based on RNA secondary structure and analyze the existence of ...
arxiv
Self-cleavage activity of the genomic HDV ribozyme in the presence of various divalent metal ions [PDF]
, 1993 Young‐Ah Suh +3 more
openalex +1 more source
A hammerhead ribozyme allows synthesis of a new form of theTetrahymenaribozyme homogeneous in length with a 3' end blocked for transesterification [PDF]
, 1991 Cheryl A. Grosshans, Thomas R. Cech
openalex +1 more source