In Vitro Aptamer Selection and Evolution using an Engineered Dual-Ribozyme Complex [PDF]
Michael Muntifering, David Wendell
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Influence of a fluorobenzene nucleobase analogue on the conformational flexibility of RNA studied by molecular dynamics simulations [PDF]
Chemically modified bases are frequently used to stabilize nucleic acids, to study the driving forces for nucleic acid structure formation and to tune DNA and RNA hybridization conditions.
Engels, Joachim W. (Prof. Dr.) +1 more
core
Construction of a ribozyme directed against human interleukin-6 mRNA: evaluation of its catalytic activity in vitro and in vivo [PDF]
M. Mahieu +4 more
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Optimized catalytic DNA-cleaving ribozymes [PDF]
The present invention discloses nucleic acid enzymes capable of cleaving nucleic acid molecules, including single-stranded DNA, in a site-specific manner under physiologic conditions, as well as compositions including same.
Joyce, Gerald F.
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Efficient In Vitro Cleavage of Mouse Acute Phase Serum Amyloid A mRNA Mediated by a Synthetic Hammerhead Ribozyme [PDF]
Derval J. Gaughan +1 more
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ESF Workshop on ‘Impact of Nucleic Acid Chemistry on Gene Function Analysis: Antisense, Aptamers, Ribozymes and RNAi’ [PDF]
Kathrin Heermeier +3 more
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Crystallization of ribozymes and small RNA motifs by a sparse matrix approach.
Jennifer A. Doudna +3 more
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Influence of ion interactions on the conformation of ribozyme specific to HIV-1 tat-RNA in solution [PDF]
O. Yu. Markelova +4 more
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Elucidating Evolutionary Mechanisms and Variants of the Hammerhead Ribozyme Using In Vitro Selection [PDF]
J. Brill, Connor Nurmi, Yingfu Li
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A Hammerhead Ribozyme That Cleaves Perforin and Fas-ligand RNAsin Vitro
Zhimei Du +3 more
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