Fast and simple purification of chemically modified hammerhead ribozymes using a lipophilic capture tag [PDF]
Brian S. Sproat+4 more
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Mini-ribozymes and freezing environment: a new scenario for the early RNA world
International audienceThe RNA World hypothesis states that the present-day life, which is based on DNA genomes and protein enzymes, was preceded by a simpler life form based primarily on RNA.
Vlassov, A. V.
core +1 more source
Explanation by a putative triester‐like mechanism for the thio effects and Mn2+ rescues in reactions catalyzed by a hammerhead ribozyme [PDF]
Demin Zhou+3 more
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Hammerhead Ribozymes: Structural Insights, Catalytic Mechanisms, and Cutting-Edge Applications in Synthetic Biology. [PDF]
Wang L, Liu Y, Xian X, Zhang H.
europepmc +1 more source
Ribozymes correctly cleave a model substrate and endogenous RNA in vivo.
Shailendra K. Saxena, E Ackerman
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In vitro selection of the Naegleria GIR1 ribozyme identifies three base changes that dramatically improve activity [PDF]
Evelyn Jabri, Thomas R. Cech
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Engineering of Small Ribozymes Acting on RNA: What is Needed to Make a New Function Work with an Existing Catalyst? [PDF]
Ebermann C, Müller S.
europepmc +1 more source
A recombinant defective adenoviral agent expressing anti‐bcl‐2 ribozyme promotes apoptosis of bcl‐2‐expressing human prostate cancer cells [PDF]
Thambi Dorai+6 more
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Chemistry and Biology of Self-Cleaving Ribozymes.
Randi M. Jimenez+2 more
semanticscholar +1 more source