Results 241 to 250 of about 34,904 (304)

A polymerase ribozyme that can synthesize both itself and its complementary strand

Gianni E, Kwok SLY, Wan CJK, Goeij K, Clifton BE, Attwater J, Holliger P.   +6 more
europepmc   +1 more source

Expression of the <i>Nicotiana benthamiana</i> Retrozyme 1 (NbRZ1) Genomic Locus. [PDF]

Plants (Basel)
Lezzhov AA, Atabekova AK, Chergintsev DA, Solovyev AG, Morozov SY.   +4 more
europepmc   +1 more source

How Droplets Can Accelerate Reactions─Coacervate Protocells as Catalytic Microcompartments. [PDF]

Acc Chem Res
Smokers IBA, Visser BS, Slootbeek AD, Huck WTS, Spruijt E.   +4 more
europepmc   +1 more source

Pioneering role of RNA in the early evolution of life. [PDF]

Genet Mol Biol
Muñoz-Velasco I, Cruz-González A, Hernández-Morales R, Campillo-Balderas JA, Cottom-Salas W, Jácome R, Vázquez-Salazar A.   +6 more
europepmc   +1 more source

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HIV and Ribozymes

Advances in Experimental Medicine and Biology, 2015
Ribozymes are structured RNA molecules that act as catalysts in different biological reactions. From simple genome cleaving activities in satellite RNAs to more complex functions in cellular protein synthesis and gene regulation, ribozymes play important roles in all forms of life.
Anne Gatignol, Robert J. Scarborough
openaire   +4 more sources

Fundamental studies of functional nucleic acids: aptamers, riboswitches, ribozymes and DNAzymes

Chemical Society Reviews, 2020
This review aims at juxtaposing common versus distinct structural and functional strategies that are applied by aptamers, riboswitches, and ribozymes/DNAzymes.
Claudia Höbartner, Ronald Micura
exaly   +2 more sources

Promiscuous Ribozymes and Their Proposed Role in Prebiotic Evolution

Chemical Reviews, 2020
The ability of enzymes, including ribozymes, to catalyze side reactions is believed to be essential to the evolution of novel biochemical activities. It has been speculated that the earliest ribozymes, whose emergence marked the origin of life, were low ...
Evan Janzen, Celia Blanco, Irene A Chen
exaly   +2 more sources

Elucidation of Catalytic Strategies of Small Nucleolytic Ribozymes from Comparative Analysis of Active Sites

ACS Catalysis, 2018
A number of small, self-cleaving ribozyme classes have been identified including the hammerhead, hairpin, hepatitis delta virus (HDV), Varkud satellite (VS), glmS, twister, hatchet, pistol, and twister sister ribozymes.
Philip C Bevilacqua
exaly   +2 more sources

New classes of self-cleaving ribozymes revealed by comparative genomics analysis

Nature Chemical Biology, 2015
Enzymes made of RNA catalyze reactions that are essential for protein synthesis and RNA processing. However, such natural ribozymes are exceedingly rare, as evident by the fact that the discovery rate for new classes has dropped to one per decade from ...
Christina E Weinberg, Kimberly A Harris, Sanshu Li   +2 more
exaly   +2 more sources

The hammerhead ribozyme [PDF]

Biopolymers, 1999
The hammerhead ribozyme is an intriguing RNA molecule with the ability to serve as a catalyst to cleave sequence-specifically RNA molecules in an intermolecular reaction. Preferentially Mg(2+) is required for optimal activity by inducing the catalytically competent conformation and by possibly acting as an acid-base catalyst.
Fritz Eckstein, Birgit Bramlage
openaire   +2 more sources