Results 21 to 30 of about 34,904 (304)
A ribozyme transcribed by a ribozyme [PDF]
Artificial DNA: PNA & XNA, 2011 Prominent current ideas on how life emerged on Earth include an RNA world hypothesis in which RNA performed informational as well as catalytic functions in the absence of both DNA and protein. Demonstration of a self-replicative system based on ribonucleic acid polymers as both information carriers and catalysts would lend support to such a scenario. A
openaire +4 more sources
Aptamers, Riboswitches, and Ribozymes in S. cerevisiae Synthetic Biology
Life, 2021 Among noncoding RNA sequences, riboswitches and ribozymes have attracted the attention of the synthetic biology community as circuit components for translation regulation.
Huanhuan Ge, Mario Andrea Marchisio
doaj +1 more source
Biochemical prevention and treatment of viral infections – A new paradigm in medicine for infectious diseases [PDF]
, 2004 For two centuries, vaccination has been the dominating approach to develop prophylaxis against viral infections through immunological prevention. However, vaccines are not always possible to make, are ineffective for many viral infections, and also carry
Fang, Fang, Le Calvez, Hervé, Yu, Mang
core +3 more sources
Development of a minigenome cassette for Lettuce necrotic yellows virus: A first step in rescuing a plant cytorhabdovirus [PDF]
, 2020 Rhabdoviruses are enveloped negative-sense RNA viruses that have numerous biotechnological applications. However, recovering plant rhabdoviruses from cDNA remains difficult due to technical difficulties such as the need for concurrent in planta ...
Drake, P +3 more
core +1 more source
Current Opinion in Structural Biology, 2007 The structural molecular biology of ribozymes took another great leap forward during the past two years. Before ribozymes were discovered in the early 1980s, all enzymes were thought to be proteins. No detailed structural information on ribozymes became available until 1994.
openaire +3 more sources
Oligonucleotide-Based Approaches to Inhibit Dengue Virus Replication
Molecules, 2021 Dengue fever is one of the most common viral infections affecting humans. It is an expanding public health problem, particularly in tropical and subtropical regions.
Kingshuk Panda +2 more
doaj +1 more source
Design and Experimental Evolution of trans-Splicing Group I Intron Ribozymes
Molecules, 2017 Group I intron ribozymes occur naturally as cis-splicing ribozymes, in the form of introns that do not require the spliceosome for their removal. Instead, they catalyze two consecutive trans-phosphorylation reactions to remove themselves from a primary ...
Ulrich F. Müller
doaj +1 more source
Molecular Cell, 2002 Twenty years have passed since the first reports that certain RNAs mediate self-splicing and precursor tRNA processing reactions in the absence of proteins. An entire field emerged to learn how RNAs that lack the chemical versatility of amino acids nonetheless assemble into enzymes that accelerate chemical reactions with efficiencies that rival those ...
Martha J. Fedor, Eric Westhof
openaire +2 more sources
Expanding the limits of the second genetic code with ribozymes
Nature Communications, 2019 The site-specific incorporation of noncanonical monomers into polypeptides through genetic code reprogramming permits synthesis of bio-based products that extend beyond natural limits.
Joongoo Lee +12 more
semanticscholar +1 more source
Force for ancient and recent life: viral and stem-loop RNA consortia promote life. [PDF]
, 2014 Lytic viruses were thought to kill the most numerous host (i.e., kill the winner). But persisting viruses/defectives can also protect against viruses, especially in a ubiquitous virosphere. In 1991, Yarmolinsky et al.
Villarreal, Luis P
core +1 more source