Results 91 to 100 of about 25,369 (260)

Chimerolectins: Classification, structural architecture, and functional perspectives

Protein Science, Volume 34, Issue 9, September 2025.
Abstract Lectins are proteins or glycoproteins capable of binding specifically and reversibly to carbohydrates, a property that, in itself, gives them great functional versatility in organisms from all kingdoms of nature. A subclass of these proteins, called chimerolectins, is composed of proteins that have at least one lectin domain associated with ...
Vanir Reis Pinto‐Junior, Benildo Sousa Cavada, Kyria Santiago Nascimento   +2 more
wiley   +1 more source

Real-time cytotoxicity assay for rapid and sensitive detection of ricin from complex matrices.

PLoS ONE, 2012
BackgroundIn the context of a potential bioterrorist attack sensitive and fast detection of functionally active toxins such as ricin from complex matrices is necessary to be able to start timely countermeasures.
Diana Pauly, Sylvia Worbs, Sebastian Kirchner, Olena Shatohina, Martin B Dorner, Brigitte G Dorner   +5 more
doaj   +1 more source

Current practice, challenges and future opportunities in the safety assessment of newly expressed proteins in genetically modified plants

EFSA Journal, Volume 23, Issue 8, August 2025.
Abstract Current risk assessment strategies for protein safety of newly expressed proteins (NEPs) in genetically modified (GM) plants are based on chemical risk assessment principles and Codex Alimentarius guidelines for biotech‐derived foods, initially published in 2003. These guidelines were designed for proteins with multiple testing options and for
EFSA Panel on Genetically Modified Organisms (GMO), Josep Casacuberta, Francisco Barro, Albert Braeuning, Ruud de Maagd, Michelle M. Epstein, Thomas Frenzel, Jean‐Luc Gallois, Frits Koning, Antoine Messéan, F. Javier Moreno, Fabien Nogué, Giovanni Savoini, Alan H. Schulman, Christoph Tebbe, Eve Veromann, Michele Ardizzone, Luca Belmonte, Martina Bonatti, Ian Dewhurst, Ivan Dimitrov, Arianna Ferrari, Tilemachos Goumperis, Kevin Hogeveen, Aleksandra Lewandowska, Robin Ornsrud, Nikoletta Papadopoulou, Konstantinos Paraskevopoulos, Tommaso Raffaello, Reinhilde Schoonjans, Elisabeth Waigmann, Elena Sánchez‐Brunete, Antonio Fernandez Dumont   +32 more
wiley   +1 more source

Tailored Watson–Crick Pairing Partners for Xanthosine in RNA

Chemistry – A European Journal, Volume 31, Issue 42, July 25, 2025.
RNAs with kappa‐xanthosine (K–X) or 2‐iminocytidine‐xanthosine (2imC–X) base pairs form stable double helices that have higher melting temperatures than those of the A–U or G–U references. Access to these novel 2imC‐modified RNAs is possible through the mild, selective chemical conversion of 2‐thiocytidine RNA precursors.
Stefan Mair, Anna Rázková, Karl Brillet, Catherina Gasser, Eric Ennifar, Ronald Micura   +5 more
wiley   +1 more source

Antibody/doxycycline combined therapy for pulmonary ricinosis: Attenuation of inflammation improves survival of ricin-intoxicated mice

Toxicology Reports, 2014
Ricin, a highly toxic plant-derived toxin, is considered a potential weapon in biological warfare due to its high availability and ease of preparation. Pulmonary exposure to ricin results in the generation of an acute edematous inflammation followed by ...
Yoav Gal, Ohad Mazor, Ron Alcalay, Nehama Seliger, Moshe Aftalion, Anita Sapoznikov, Reut Falach, Chanoch Kronman, Tamar Sabo   +8 more
doaj   +1 more source

Chemical Components of the Dried Latex of Euphorbia resinifera Berg and Its Medicinal Features

Chemistry &Biodiversity, Volume 22, Issue 7, July 2025.
ABSTRACT A great deal of research has been carried out on the latex of Euphorbia resinifera Berg, which is an important source of several compounds of therapeutic and medicinal interest. Extraction, synthesis, and hemi synthesis pathways continue to reveal the existence of other new products with anticancer, antioxidant, antidiuretic, and antimalarial ...
Doaa Hammad, El‐Mahdi Ourhzif, Salha Hamri, Hafid Abderrafia, Mostafa Khouili, Maria Dolors Pujol   +5 more
wiley   +1 more source

Total Body Irradiation Mitigates Inflammation and Extends the Therapeutic Time Window for Anti-Ricin Antibody Treatment against Pulmonary Ricinosis in Mice

Toxins, 2017
Ricin, a highly toxic plant-derived toxin, is considered a potential weapon in biowarfare and bioterrorism due to its pronounced toxicity, high availability, and ease of preparation.
Yoav Gal, Anita Sapoznikov, Reut Falach, Sharon Ehrlich, Moshe Aftalion, Chanoch Kronman, Tamar Sabo   +6 more
doaj   +1 more source

A Critical Overview of Common Foodborne Toxicants and Methods for Their Reliable Detection

Food Frontiers, Volume 6, Issue 4, Page 1658-1700, July 2025.
ABSTRACT Food is an essential commodity for human health. However, toxicants such as mycotoxins, heavy metals, acrylamide, and pesticides can be present in food either naturally or through processing, packaging, or some anthropogenic activities. A thorough review of carefully selected studies revealed that climate change and pandemics have led to an ...
Betty Bowe Acquah, John‐Lewis Zinia Zaukuu   +1 more
wiley   +1 more source

Ready or Not? Protecting the Public's Health in the Age of Bioterrorism, 2004 [PDF]

, 2004
Examines ten key indicators to evaluate state preparedness to respond to bioterrorist attacks and other public health emergencies.
Laura M. Segal, Michael J. Earls, Patti J. Unruh, Shelley A. Hearne   +3 more
core  

How are proteins reduced in the endoplasmic reticulum? [PDF]

, 2018
The reversal of thiol oxidation in proteins within the endoplasmic reticulum (ER) is crucial for protein folding, degradation, chaperone function, and the ER stress response. Our understanding of this process is generally poor but progress has been made.
Bulleid, Neil, Ellgaard, Lars, Sevier, Carolyn S.   +2 more
core   +2 more sources