Results 91 to 100 of about 46,701 (237)
Clinical and Translational Science, Volume 19, Issue 2, February 2026.ABSTRACT ASP1617 is a novel, highly selective inhibitor of cathepsin‐S, an important protease for antigen peptide loading onto major histocompatibility complex class II molecules. Preclinically, ASP1617 prevented progression of lupus‐like glomerulonephritis in an NZB/W F1 mouse model of systemic lupus erythematosus.
Tomoki Kojima +9 more
wiley +1 more source
Pacific Blue Derivatives of Paclitaxel as Fluorescent Probes of OATP1B‐Type Transporters
Clinical and Translational Science, Volume 19, Issue 2, February 2026.ABSTRACT Paclitaxel (Taxol) is a widely used anticancer agent that undergoes extensive hepatic metabolism and that causes a debilitating, dose‐limiting peripheral neurotoxicity. We previously reported that the uptake of paclitaxel in hepatocytes and dorsal root ganglion neurons, the site of injury within the nervous system, is mediated by the organic ...
Mahesh R. Nepal +11 more
wiley +1 more source
The Effect of Ecopipam on the Pharmacokinetics of Concomitant Medications
Clinical and Translational Science, Volume 19, Issue 2, February 2026.ABSTRACT Ecopipam is a first‐in‐class dopamine D1 receptor antagonist under investigation for the treatment of Tourette syndrome. This open‐label, fixed‐sequence, three‐cohort study evaluated whether ecopipam induces or inhibits cytochrome P450 (CYP) 1A2, CYP2B6, CYP2C19, CYP2D6, CYP3A4, organic anion‐transporting polypeptide (OATP) 1B1, and p ...
Virginia D. Schmith +4 more
wiley +1 more source
Equine Veterinary Education, Volume 38, Issue 2, Page e70-e77, February 2026.Summary Two foals were being treated with a combination of oral doxycycline and rifampin for presumed Rhodococcus equi infections. After 3–4 weeks of antimicrobial administration, both foals presented with icterus and nonspecific clinical signs, including lethargy and inappetence.
A. Murdock +7 more
wiley +1 more source
Journal of Hospital Medicine, Volume 21, Issue 2, Page 200-204, February 2026.
Gurpreet Dhaliwal +4 more
wiley +1 more source
Journal of the World Aquaculture Society, Volume 57, Issue 1, February 2026.Abstract Members of Bacillus cereus have been documented as important bacterial pathogens in aquaculture. However, scarce information is available on B. cereus isolates as causal pathogens of big‐belly seahorses Hippocampus abdominalis. In the present study, a B. cereus isolate (SH1), recovered from a disease outbreak on a seahorse farm, was identified
Chunlei Gai +7 more
wiley +1 more source
Evaluation of the effect of rifampin on the pharmacokinetics of the Smoothened inhibitor glasdegib in healthy volunteers [PDF]
, 2018 M. Naveed Shaik +3 more
openalex +1 more source
Liquid Chromatographic Determination of Rifampin In Human Plasma, Bronchoalveolar Lavage Fluid, and Alveolar Cells [PDF]
, 2000 John E. Conte, E T Lin, E. Zurlinden
openalex +1 more source
191. High-Dose Rifampin-containing Regimens for the Treatment of TB Meningitis [PDF]
, 2021 Camilo A. Ruiz-Bedoya +16 more
openalex +1 more source