Results 91 to 100 of about 72,471 (294)

Dithiolopyrrolone Natural Products : Isolation, Synthesis and Biosynthesis [PDF]

open access: yes, 2013
Peer reviewedPublisher ...
Deng, Hai   +3 more
core   +2 more sources

Comparative Analysis of Isavuconazole DDIs With Other Azole Antifungal Drugs and PBPK Model‐Informed Dosing Recommendations for Anticancer Drugs

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Isavuconazole is a broad‐spectrum triazole approved for the treatment of invasive aspergillosis or mucormycosis in adults and children aged ≥ 1 year. Current prescribing information lacks guidance regarding the co‐administration of isavuconazole with anticancer drugs–limited by the availability of clinical drug–drug interaction (DDI) data in ...
Theunis C. Goosen   +6 more
wiley   +1 more source

Antimicrobial Treatment of Orthopedic Implant-related Infections with Rifampin Combinations [PDF]

open access: yes, 2017
The purpose of this prospective clinical study is to evaluate the role of combination chemotherapy with rifampin in the treatment of orthopedic device—related infections in which the implant could not be removed.
Gaechter, Andre   +3 more
core  

Microscopic Observation Drug Susceptibility Assay for Rapid Diagnosis of Lymph Node Tuberculosis and Detection of Drug Resistance. [PDF]

open access: yes, 2015
In this study, 132 patients with lymphadenopathy were investigated. Fifty-two (39.4%) were diagnosed with tuberculosis (TB). The microscopic observation drug susceptibility (MODS) assay provided rapid (13 days), accurate diagnosis (sensitivity, 65.4 ...
Cabrera, JL   +12 more
core   +3 more sources

Outcomes following exposure to drug interactions with ibrutinib in patients with chronic lymphocytic leukaemia

open access: yesBritish Journal of Haematology, EarlyView.
Summary Ibrutinib is metabolized by cytochrome P450 3A (CYP3A) and poses challenges with drug interactions. We conducted a population‐based cohort study of Ontario residents aged ≥66 years who initiated ibrutinib for chronic lymphocytic leukaemia (CLL) to evaluate the frequency of potential drug interactions involving moderate/strong CYP3A inhibitors ...
Tuan Hoang   +10 more
wiley   +1 more source

New combination for patients with latent tuberculosis infection: A pilot study

open access: yesJournal of Medical Sciences, 2018
Background: Latent tuberculosis infection (LTBI) is characterized by the presence of immune responses to Mycobacterium tuberculosis without clinical evidence of active TB.
Te-Yu Lin, Feng-Cheng Liu
doaj   +1 more source

Aspergillosis of the CNS in a pediatric liver transplant recipient: Case report and review [PDF]

open access: yes, 1991
A 2-month-old infant who had undergone orthotopic liver transplantation at the age of 2 weeks for carbamoyl phosphate synthetase deficiency developed infection of the CNS due to Aspergillus fumigatus.
Green, M   +4 more
core   +1 more source

Red urine in a 68‐year‐old man with amyotrophic lateral sclerosis

open access: yes
Journal of General and Family Medicine, EarlyView.
Kento Furuya, Naoya Itoh
wiley   +1 more source

The Influence of Health Literacy on the Control of Hypothyroidism in Patients Under Levothyroxine Treatment

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective To investigate the association between health literacy levels and biochemical control of hypothyroidism, measured by serum TSH and free thyroxine (FT4) levels, in patients receiving levothyroxine (L‐T4) therapy. Methods We conducted a cross‐sectional study at the Thyroid Disorders Outpatient Clinic, Escola Paulista de Medicina ...
Jessyka Krause Meneses   +4 more
wiley   +1 more source

Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis [PDF]

open access: yes, 2015
Supported by the Global Alliance for TB Drug Development with support from the Bill and Melinda Gates Foundation, the European and Developing Countries Clinical Trials Partnership, U.S. Agency for International Development, U.K.
Crook, Angela M.   +9 more
core   +1 more source

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