Results 91 to 100 of about 86,105 (313)

Tuberculous Pericarditis [PDF]

open access: yes, 2018
info:eu-repo/semantics ...
Faria, D, Freitas, A
core   +1 more source

Double-Blind, Randomized, Placebo-Controlled Phase II Dose-Finding Study To Evaluate High-Dose Rifampin for Tuberculous Meningitis

open access: yesAntimicrobial Agents and Chemotherapy, 2018
High doses of rifampin may help patients with tuberculous meningitis (TBM) to survive. Pharmacokinetic pharmacodynamic evaluations suggested that rifampin doses higher than 13 mg/kg given intravenously or 20 mg/kg given orally (as previously studied) are
S. Dian   +12 more
semanticscholar   +1 more source

Clinical Evaluation of Drug–Drug Interactions Between Bictegravir and Strong Inhibitors/Inducers of the CYP3A4, UGT1A1, or P‐gp Pathways

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract In addition to antiretroviral therapy (ART), people with HIV often take medications to treat comorbidities. It is therefore important to assess these medications for potential drug‐drug interactions, which may affect the safety and efficacy of ART. Three phase I studies were conducted in adult participants without HIV. The pharmacokinetics (PK)
Priyanka Arora   +4 more
wiley   +1 more source

Deciphering the Molecular Basis for Attenuation of Flavobacterium columnare Strain Fc1723 Used as Modified Live Vaccine against Columnaris Disease

open access: yesVaccines, 2021
Vaccines are widely employed in aquaculture to prevent bacterial infections, but their use by the U.S. catfish industry is very limited. One of the main diseases affecting catfish aquaculture is columnaris disease, caused by the bacterial pathogen ...
Wenlong Cai, Covadonga R. Arias
doaj   +1 more source

Antimicrobial effects of folk medicinal plants from the North of Iran against Mycobacterium tuberculosis [PDF]

open access: yes, 2015
Background: Medicinal plants have been used traditionally in Golestan province (north of Iran), against Mycobacterium tuberculosis or the clinical signs of tuberculosis (TB).
Davoodi, H.   +6 more
core  

Structural Implications of Mutations Conferring Rifampin Resistance in Mycobacterium leprae

open access: yesScientific Reports, 2018
The rpoB gene encodes the β subunit of RNA polymerase holoenzyme in Mycobacterium leprae (M. leprae). Missense mutations in the rpoB gene were identified as etiological factors for rifampin resistance in leprosy.
S. Vedithi   +11 more
semanticscholar   +1 more source

Is It an Intrapericardial Mass or a Localized Pericardial Effusion? A Case Report of Tuberculous Pericarditis Evaluated by Multimodal Imaging

open access: yesJournal of Clinical Ultrasound, EarlyView.
Tuberculous pericarditis is a common type of pericarditis, but it is difficult to be diagnosed. The application of combined transesophageal echocardiography, contrast echocardiography, and CT multimodal imaging provides sufficient clinical diagnosis basis and guidance for distinguishing encapsulated pericardial effusion or mass.
Yang Han   +5 more
wiley   +1 more source

Use of rifampin in persistent coagulase negative staphylococcal bacteremia in neonates

open access: yesBMC Pediatrics, 2010
Background Coagulase negative staphylococci (CoNS) are the most common cause of neonatal sepsis in the Neonatal Intensive Care Unit (NICU). A minority of neonates does not respond to vancomycin therapy and develops persistent bacteremia, which may be ...
Walther Frans J   +2 more
doaj   +1 more source

Rifampin enhances cytochrome P450 (CYP) 2B6-mediated efavirenz 8-hydroxylation in healthy volunteers [PDF]

open access: yes, 2016
The effect of rifampin on the in vivo metabolism of the antiretroviral drug efavirenz was evaluated in healthy volunteers. In a cross-over placebo control trial, healthy subjects (n = 20) were administered a single 600 mg oral dose of efavirenz after ...
Blievernicht, Julia   +10 more
core   +1 more source

Evolution of Rifampin Resistance in Escherichia coli and Mycobacterium smegmatis Due to Substandard Drugs

open access: yesAntimicrobial Agents and Chemotherapy, 2018
Poor-quality medicines undermine the treatment of infectious diseases, such as tuberculosis, which require months of treatment with rifampin and other drugs. Rifampin resistance is a critical concern for tuberculosis treatment.
Zohar B. Weinstein, M. Zaman
semanticscholar   +1 more source

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