Rifampin-resistant Meningococcal Disease
Emerging Infectious Diseases, 2005 Rifampin-resistant meningococcal disease occurred in a child who had completed rifampin chemoprophylaxis for exposure to a sibling with meningococcemia. Susceptibility testing of 331 case isolates found only 1 other case of rifampin-resistant disease in ...
Jean Rainbow +5 more
doaj +2 more sources
Prediction of Rivaroxaban-Rifampin Interaction After Major Orthopedic Surgery: Physiologically Based Pharmacokinetic Modeling and Simulation [PDF]
Frontiers in Pharmacology, 2021 Rivaroxaban is commonly used for the prophylaxis of venous thromboembolism (VTE) for patients undergoing major orthopedic surgery. Rivaroxaban is primarily eliminated by hepatic CYP450 metabolism and renal excretion.
Rui-juan Xu +5 more
doaj +2 more sources
Physiologically Based Pharmacokinetic Modeling to Assess Transporter-Mediated Drug-Drug Interactions in Support of Labeling Recommendations for Zavegepant Nasal Spray. [PDF]
Clin Pharmacol TherZavegepant nasal spray, a calcitonin gene‐related peptide receptor antagonist indicated for acute treatment of migraine with or without aura in adults, is a substrate for organic anion transporting polypeptide 1B3 (OATP1B3), Na+/taurocholate cotransporting polypeptide (NTCP), P‐glycoprotein (P‐gp), and cytochrome P450 3A4 (CYP3A4).
Ke A +8 more
europepmc +2 more sources
Culture-Negative Infective Endocarditis Presumed due to Brucella Causing Rapid Native Aortic Valve Destruction in a Young Adult: A Case Report. [PDF]
Clin Case RepABSTRACT Culture‐negative endocarditis with features consistent with Brucella can rapidly destroy a normal aortic valve in young adults. 2023 Duke‐ISCVID criteria (clinical/imaging findings plus histopathology), supported by serology and occupational exposure enabled urgent combined antimicrobial‐surgical management without culture confirmation ...
Nassar B +5 more
europepmc +2 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
A Case of Atypical Delayed Anaphylaxis to Rifampin [PDF]
, 2023 Rifampin is a mainstay in anti-tuberculosis therapy and is generally well tolerated and safe to take at therapeutic dosing. While anaphylactic reactions to rifampin are exceedingly rare, prompt recognition and awareness is vital to patient safety, and ...
Jessica Sworzyn +4 more
core +1 more source
Frontiers in Pharmacology, 2016 Membrane drug transporters contribute to the disposition of many drugs. In human liver, drug transport is controlled by two main superfamilies of transporters, the solute carrier transporters (SLC) and the ATP Binding Cassette transporters (ABC). Altered
Eric A Benson +8 more
doaj +1 more source
PLoS ONE, 2020 BACKGROUND:Staphylococcus aureus (S. aureus) bacteremia (SAB) has high morbidity and mortality, with the development of methicillin-resistant S. aureus (MRSA) and the recognized shortcomings of vancomycin, its management is becoming more complicated ...
Huan Ma +5 more
doaj +1 more source
A literature review of liver function test elevations in rifampin drug–drug interaction studies
Clinical and Translational Science, 2022 Although rifampin drug–drug interaction (DDI) studies are routinely conducted, there have been instances of liver function test (LFT) elevations, warranting further evaluation.
Sherry M. Ibrahim +3 more
doaj +1 more source