Results 81 to 90 of about 46,701 (237)

Fast parallel quantification of dual drug systems via UV-VIS spectrometry – a case study with antibiotic substances

Current Directions in Biomedical Engineering, 2017
Implant-based drug delivery necessitates a rigorous quantitative assessment and quality control of the drug release behavior. In this context, a fast simultaneous UV-VIS spectrometer quantification method was developed for an antibiotic dual drug system.
Eickner Thomas, Reske Thomas, Illner Sabine, Schmitz Klaus-Peter, Martin David P., Grabow Niels   +5 more
doaj   +1 more source

Fluorescent Protein Expressing Rickettsia buchneri and Rickettsia peacockii for Tracking Symbiont-Tick Cell Interactions

Veterinary Sciences, 2016
Rickettsiae of indeterminate pathogenicity are widely associated with ticks. The presence of these endosymbionts can confound a One Health approach to combatting tick-borne diseases.
Timothy J. Kurtti, Nicole Y. Burkhardt, Chan C. Heu, Ulrike G. Munderloh   +3 more
doaj   +1 more source

Population pharmacokinetic modeling of isoniazid, rifampin, and pyrazinamide [PDF]

, 1997
Charles A. Peloquin, George S. Jaresko, Lip Yong Chung, Anther Keung, Amy E. Bulpitt, Roger W. Jelliffe   +5 more
openalex   +1 more source

The Spectrum of Spontaneous Rifampin Resistance Mutations in the Bacillus subtilis rpoB Gene Depends on the Growth Environment

, 2021
Joss D. Leehan, Wayne L. Nicholson
openalex   +2 more sources

A 24-Week, All-Oral Regimen for Rifampin-Resistant Tuberculosis [PDF]

, 2022
Bern-Thomas Nyang’wa, Catherine Berry, Emil Kazounis, Ilaria Motta, Nargiza Parpieva, Zinaida Tigay, Varvara Solodovnikova, Irina Liverko, Ronelle Moodliar, Matthew Dodd, Nosipho Ngubane, Mohammed Rassool, Timothy D. McHugh, Melvin Spigelman, David Moore, Koert Ritmeijer, Philipp du Cros, Katherine Fielding   +17 more
openalex   +1 more source

Frontiers in the Management of Orthopaedic Periprosthetic Joint Infection

Journal of Orthopaedic Research, Volume 44, Issue 2, February 2026.
ABSTRACT Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty (TJA), one of the most frequently performed surgical procedures worldwide. Management of acute PJI commonly involves debridement, antibiotics, and implant retention (DAIR), though failure rates remain high due to antibiotic‐tolerant biofilms. Chronic
Michael F. Shannon, Victoria R. Wong, Samuelson E. Osifo, Timothy Edwards, Himanshu Rao, Jewelia Rempuszewski, Andrew J. Frear, Shaan Sadhwani, Neel B. Shah, Kenneth L. Urish   +9 more
wiley   +1 more source

Konstruksi mutasi daerah resisten rifampin (gen rpoB) dari Mycobacterium leprae pada penderita lepra di Surabaya melalui analisis genom hasil PCR

Journal of Biological Researches, 2012
Rifampin is a key component in the chemoterapeutic regimens used to combat both leprosy and tuberculosis. Owing to exquisite rifampin susceptibility of Mycobacterium leprae, this drug is the backbone of the multidrug therapy currently recommended by WHO
E Bimo Aksono H
doaj   +1 more source

Effect of Testosterone Therapy on Cytochrome P450 3A and P‐Glycoprotein Activities Using Midazolam and Digoxin as Probe Substrates Among Transgender Adults

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 2, February 2026.
ABSTRACT Background Gender‐affirming testosterone therapy is one part of the standard of care for more than 1 million transgender adults in the United States. Testosterone therapy may influence the activities of drug‐metabolizing enzymes and transporters, but knowledge about its effect on the pharmacokinetics of other medications is limited.
Michiko Hunter, Rene Coig, Linda Risler, Kristen K. Patton, Radhika R. Narla, Dina N. Greene, Alson K. Burke, Elizabeth Micks, Mary F. Hebert, Lauren R. Cirrincione   +9 more
wiley   +1 more source

Beyond the Michaelis–Menten: Evaluation of a tQSSA‐Based IVIVE Approach for Predicting In Vivo Intrinsic Clearance From Hepatocyte Assays

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT The classical Michaelis–Menten model, under the standard quasi‐steady‐state approximation (sQSSA), is widely used in in vitro‐in vivo extrapolation (IVIVE) studies using hepatocyte or human liver microsomal (HLM) assays to predict intrinsic hepatic clearance (Clint,vitro$$ {\mathrm{Cl}}_{\operatorname{int},\mathrm{vitro}} $$).
Ngoc‐Anh Thi Vu, Yun Min Song, Sang Kyum Kim, Hwi‐yeol Yun, Soyoung Lee, Jae Kyoung Kim, Jung‐woo Chae   +6 more
wiley   +1 more source

The Influence of Health Literacy on the Control of Hypothyroidism in Patients Under Levothyroxine Treatment

Clinical Endocrinology, Volume 104, Issue 2, Page 167-174, February 2026.
ABSTRACT Objective To investigate the association between health literacy levels and biochemical control of hypothyroidism, measured by serum TSH and free thyroxine (FT4) levels, in patients receiving levothyroxine (L‐T4) therapy. Methods We conducted a cross‐sectional study at the Thyroid Disorders Outpatient Clinic, Escola Paulista de Medicina ...
Jessyka Krause Meneses, Daniella Araujo Muniz, Débora Moroto, João Roberto Maciel Martins, Carolina Castro Porto Silva Janovsky   +4 more
wiley   +1 more source