Results 91 to 100 of about 7,735 (212)
Process Investigations on the One-Pot Synthesis of Rifamycin S Avoiding Chlorinated Solvents [PDF]
, 2015 The facile synthesis of rifamycin S from rifamycin B, a member of the ansamycin family of antibiotics, via the oxidation of rifamycin B was developed. Currently on an industrial scale, this oxidation is performed using harsh pH conditions and chlorinated
Ferdinand Zepeck (1479463) +4 more
core +1 more source
Microbiology ResearchPouchitis is one of the most common long-term complications after ileal pouch–anal anastomosis (IPAA) surgery, with a reported incidence rate of up to 50%. Identifying specific bacteria involved in the pathogenesis has important implications for clinical
Caterina Aiello +5 more
doaj +1 more source
A Sorption Study between Ophthalmic Drugs and Multi Dose Eyedroppers in Simulated Use Conditions
Pharmaceutical Technology in Hospital Pharmacy, 2017 Preservative free ophthalmic formulations need to be packaged either as single doses, or using specially designed sterility preserving multidose eyedroppers.
Le Basle Yoann +2 more
doaj +1 more source
Emerging Infectious Diseases, 2019 Surveys suggest that clinicians diverge from guidelines when treating Mycobacterium avium complex (MAC) pulmonary disease (PD). To determine prescribing patterns, we conducted a cohort study of adults >66 years of age in Ontario, Canada, with MAC or ...
Sarah K. Brode +7 more
doaj +1 more source
Rifamycins, Alone and in Combination [PDF]
Cold Spring Harbor Perspectives in Medicine, 2016 Rifamycins inhibit RNA polymerase of most bacterial genera. Rifampicin remains part of combination therapy for treating tuberculosis (TB), and for treating Gram-positive prosthetic joint and valve infections, in which biofilms are prominent. Rifabutin has use for AIDS patients in treating mycobacterial infections TB and Mycobacterium avium complex (MAC)
openaire +2 more sources
Development of Rifampicin Eye Drops for the Treatment of Exudative Age-Related Macular Degeneration
PharmaceuticalsBackground/Objectives: Exudative age-related macular degeneration (AMD) is a disease of choroidal neovascularization that causes blindness. Current treatments to preserve vision in this prevalent and blinding condition are repeat intraocular injections ...
Valory Anne S. Vailoces +9 more
doaj +1 more source
Host risk factors for rifamycin-resistant clostridium difficile infection: A case control study [PDF]
, 2009 Objective. To evaluate the host risk factors associated with rifamycin-resistant Clostridium difficile (C. diff) infection in hospitalized patients compared to rifamycin-susceptible C.diff infection. Background. C. diff is the most common definable cause
Yadav, Yashoo
core
Inhibition of mutation and combating the evolution of antibiotic resistance.
PLoS Biology, 2005 The emergence of drug-resistant bacteria poses a serious threat to human health. In the case of several antibiotics, including those of the quinolone and rifamycin classes, bacteria rapidly acquire resistance through mutation of chromosomal genes during ...
Ryan T Cirz +5 more
doaj +1 more source
Biological activity of a new class of rifamycins Spiro-piperidyl-rifamycins.
The Journal of Antibiotics, 1980 The biological properties of spiro-piperidyl-rifamycins, a new class of rifamycin antibiotics, are described. In these derivatives the positions 3 and 4 have been incorporated into an imidazolyl ring bearing a spiro-piperidyl group N substituted with linear and branched aliphatic chains. The in vitro antibacterial activity against Staphylococcus aureus
A, Sanfilippo +6 more
openaire +3 more sources
Enzymatic conversion of rifamycin B in a rotating packed disk reactor [PDF]
, 1986 The biological conversion of rifamycin B to rifamycin S was attempted using immobilized rifamycin B oxidase in a rotating packed disk reactor (RPDR). Humicola sp.
Bong Hyun Chung +2 more
core +1 more source