Results 151 to 160 of about 7,735 (212)
, 2010 Disclosed are compounds including rifamycin derivatives having antibacterial activities, wherein the compounds have the following general formula (I) wherein: R is hydrogen or acetyl R1 and R2 are independently selected from the group consisting of hydrogen, ( C1-4) alkyl, benzyloxy, mono- and di-(C1-3) alkylamino-(C1-4)alkyl, (C1-3)alkoxy, (C1-4 ...
M. Campana +5 more
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Rifamycin B. oxidase fromMonocilliumspp., a new type of diphenol oxidase [PDF]
FEBS Letters, 1983 It was found that enzyme from a microbial strain, Monocillium spp. ATCC 20621, catalyzed the oxidative reaction of rifamycin B to form rifamycin O.
M H Han, Seong Baik-Lin
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Biogenesis of rifamycins. The conversion of rifamycin B into rifamycin Y
Experientia, 1967E stata studiata la biogenesi della rifamicina Y, prodotta accanto alla rifamicina B da culture diS. mediterranei. I dati riportati dimostrano che la rifamicina Y deriva dalla rifamicina Be che la sua produzione dipende dalla concentrazione di fosfati nel terreno di cultura.
G C, Lancini +3 more
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Screening of rifamycin producing marine sponge bacteria by LC–MS–MS [PDF]
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2007 HPLC-MS-MS has been used for the identification and characterisation of rifamycin B and rifamycin SV in various strains of the marine sponge-derived bacterium Salinispora.
Amitha K Hewavitharana +2 more
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RifZ (AMED_0655) Is a Pathway-Specific Regulator for Rifamycin Biosynthesis in Amycolatopsis mediterranei [PDF]
Applied and Environmental Microbiology, 2017 Rifamycin and its derivatives are particularly effective against the pathogenic mycobacteria Mycobacterium tuberculosis and Mycobacterium leprae .
Chen Li, Xinqiang Liu, Chao Lei
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Molecular Immunology, 1979
Abstract The presence of anti-rifamycin antibodies in sera of rabbits injected with a rifamycin-protein conjugate or with some unconjugated rifamycin derivatives, was assayed by equilibrium dialysis. The conjugate was effective in eliciting the production of rifamycin specific antibodies. This capacity also was exhibited by the derivatives P and S/TA.
G, Mistrello +4 more
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Abstract The presence of anti-rifamycin antibodies in sera of rabbits injected with a rifamycin-protein conjugate or with some unconjugated rifamycin derivatives, was assayed by equilibrium dialysis. The conjugate was effective in eliciting the production of rifamycin specific antibodies. This capacity also was exhibited by the derivatives P and S/TA.
G, Mistrello +4 more
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Rifamycins LXI: In vivo inhibition of RNA synthesis by rifamycins
Experientia, 1968L'azione della rifampicina e della rifamide su batteri in fase logaritmica e stato studiato determinando l'effetto sull'incorporazione di uracile, timina, fenilalanina e uridina-trifostato marcati con C14 da parte di colture diE. coli eB. subtilis. I risultati indicano che il blocco della sintesi dell'RNA precede quello della sintesi delle proteine e ...
G C, Lancini, G, Sartori
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Annual Review of Microbiology, 1972
INTRODUCTION ...... . CHEMISTRy ...... . 199 200 RELATIONSHIPS BETWEEN CHEMICAL STRUCTURE AND ANTIBACTERIAL ACTIVITY.. 202 MECHANISM OF ANTIBACTERIAL ACTION. . . . . . . . 205 Activity 0/1 whole cells. . . . . . . . . .. . . . . . . . . . . 205 Activity Oil DNA-depelldellf RNA polymerase. 205 MUTATION TO RIFAMPICIN RESISTANCE. . . . . .
S, Riva, L G, Silvestri
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INTRODUCTION ...... . CHEMISTRy ...... . 199 200 RELATIONSHIPS BETWEEN CHEMICAL STRUCTURE AND ANTIBACTERIAL ACTIVITY.. 202 MECHANISM OF ANTIBACTERIAL ACTION. . . . . . . . 205 Activity 0/1 whole cells. . . . . . . . . .. . . . . . . . . . . 205 Activity Oil DNA-depelldellf RNA polymerase. 205 MUTATION TO RIFAMPICIN RESISTANCE. . . . . .
S, Riva, L G, Silvestri
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Rifamycins – Obstacles and opportunities
Tuberculosis, 2010With nearly one-third of the global population infected by Mycobacterium tuberculosis, TB remains a major cause of death (1.7 million in 2006). TB is particularly severe in parts of Asia and Africa where it is often present in AIDS patients. Difficulties in treatment are exacerbated by the 6-9 month treatment times and numerous side effects.
Paul A, Aristoff +3 more
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