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Biogenesis of rifamycins. The conversion of rifamycin B into rifamycin Y
Experientia, 1967E stata studiata la biogenesi della rifamicina Y, prodotta accanto alla rifamicina B da culture diS. mediterranei. I dati riportati dimostrano che la rifamicina Y deriva dalla rifamicina Be che la sua produzione dipende dalla concentrazione di fosfati nel terreno di cultura.
G C, Lancini +3 more
openaire +2 more sources
Molecular Immunology, 1979
Abstract The presence of anti-rifamycin antibodies in sera of rabbits injected with a rifamycin-protein conjugate or with some unconjugated rifamycin derivatives, was assayed by equilibrium dialysis. The conjugate was effective in eliciting the production of rifamycin specific antibodies. This capacity also was exhibited by the derivatives P and S/TA.
G, Mistrello +4 more
openaire +2 more sources
Abstract The presence of anti-rifamycin antibodies in sera of rabbits injected with a rifamycin-protein conjugate or with some unconjugated rifamycin derivatives, was assayed by equilibrium dialysis. The conjugate was effective in eliciting the production of rifamycin specific antibodies. This capacity also was exhibited by the derivatives P and S/TA.
G, Mistrello +4 more
openaire +2 more sources
In vitro antimycobacterial activity of newly synthesised S-alkylisothiosemicarbazone derivatives and synergistic interactions in combination with rifamycins against Mycobacterium avium [PDF]
The antimycobacterial activities of two new S-alkylisothiosemicarbazone derivatives (1i and 1f) against 32 Mycobacterium avium isolates were investigated. The minimum inhibitory concentrations (MICs) were significantly lower than those of rifampicin and
Alessandro De Logu +2 more
exaly +2 more sources
Rifamycins LXI: In vivo inhibition of RNA synthesis by rifamycins
Experientia, 1968L'azione della rifampicina e della rifamide su batteri in fase logaritmica e stato studiato determinando l'effetto sull'incorporazione di uracile, timina, fenilalanina e uridina-trifostato marcati con C14 da parte di colture diE. coli eB. subtilis. I risultati indicano che il blocco della sintesi dell'RNA precede quello della sintesi delle proteine e ...
G C, Lancini, G, Sartori
openaire +2 more sources
2010
Disclosed are compounds including rifamycin derivatives having antibacterial activities, wherein the compounds have the following general formula (I) wherein: R is hydrogen or acetyl R1 and R2 are independently selected from the group consisting of hydrogen, ( C1-4) alkyl, benzyloxy, mono- and di-(C1-3) alkylamino-(C1-4)alkyl, (C1-3)alkoxy, (C1-4 ...
M. Campana +5 more
openaire +3 more sources
Disclosed are compounds including rifamycin derivatives having antibacterial activities, wherein the compounds have the following general formula (I) wherein: R is hydrogen or acetyl R1 and R2 are independently selected from the group consisting of hydrogen, ( C1-4) alkyl, benzyloxy, mono- and di-(C1-3) alkylamino-(C1-4)alkyl, (C1-3)alkoxy, (C1-4 ...
M. Campana +5 more
openaire +3 more sources

