Results 31 to 40 of about 2,225,816 (243)

Research on the Nonlinear Structural Dynamic Characteristics of the Rigid Flexible Coupling Folding Wing Model for Aircraft

Engineered Science
During the working process of the folding wing, there is not only a large-range rigid body motion but also a deformation motion of the flexible components. The problem of the rigid-flexible coupling of the structure is extremely complex.
Xinqiang Lu, Rui Yang, Shiyong Sun
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Piezoelectric Sensing of Rigid-Flexible Coupled Free-Edge Rectangular Plates

International Journal of Aerospace Engineering
With the rapid development of space technology, rigid-flexible coupling systems are widely used in aerospace structures. Attitude-vibration coupling control requires a deep understanding of the rigid-flexible coupling dynamics of these systems.
Yudong Hu, Haoran Li
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Patient comfort during flexible and rigid cystourethroscopy [PDF]

, 2016
Introduction : Cystourethroscopy (CS) is an endoscopic method used to visualize the urethra and the bladder. Aim: In this study , we prospectively evaluated pain in men undergoing cyclic cystoscopic assessment with rigid and flexible instruments after ...
Krzysztof Tupikowski, Bartosz Małkiewicz, Wojciech Krajewski, Michał Matuszewski, Janusz Dembowski, Anna Kołodziej, Katarzyna Kościelska, Joanna Wojciechowska, Romuald Zdrojowy   +8 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Dynamic Modeling and Simulation of a Rotating Single Link Flexible Robotic Manipulator Subject to Quick Stops [PDF]

, 2014
Single link robotic manipulators are extensively used in industry and research operations. The main design requirement of such manipulators is to minimize link dynamic deflection and its active end vibrations, and obtain high position accuracy during its
Noroozi, Siamak, Dupac, Mihai
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Dynamic modelling and control for fully-steerable large reflector antenna considering rigid-flexible coupling [PDF]

, 2017
As the size of reflector antenna increases, the influence of flexible deformation to the system dynamics is much more significant. The coupling between the flexible deformation and the rigid displacement needs to be considered.
Congsi Wang, Hong Bao, Sulan Li, Bao, Hong, Li, Sulan, Wang, Congsi   +5 more
core   +2 more sources