Molecular complete response to the RIN protocol (regorafenib, ipilimumab, and nivolumab) in a patient with advanced recurrent metastatic mismatch repair proficient/microsatellite stable (pMMR/MSS) rectal cancer. [PDF]
Qadri F +7 more
europepmc +1 more source
Deterministic Fiber‐Optic Spectral Engineering Enables Three‐Color Multiplexed Two‐Photon Microscopy
A simulation‐guided spectral‐engineering framework maps the nonlinear parameter space of a fiber laser platform to identify balanced three‐band excitation states. The resulting 960, 1080, and 1175 nm femtosecond pulses deliver nJ‐level energies for low‐cross‐talk chromatically multiplexed two‐photon microscopy.
Marvin Edelmann +5 more
wiley +1 more source
De novo transcriptome assembly of Clitoria ternatea flowers. [PDF]
Singaram N +3 more
europepmc +1 more source
A schematic diagram illustrating the KMT5C‐H4K20me3‐EWSR1‐ACADM signaling axis and its role in ccRCC progression. Key Outcomes: KMT5C/H4K20me3 are upregulated in ccRCC and predict poor prognosis. EWSR1 is a novel noncanonical H4K20me3 reader in ccRCC. KMT5C/EWSR1 co‐repress ACADM via transcription and m6A modification. A‐196 + sunitinib synergistically
Chengjian Ji +10 more
wiley +1 more source
Alphavirus nsP3 as a multifunctional orchestrator of virus-host interplay. [PDF]
Pimenta-Pereira AA +2 more
europepmc +1 more source
Transcriptome sequencing of Ceutorhynchus obstrictus revealed RNA interference (RNAi) targets; double‐stranded RNA microinjection reduced transcript levels and increased mortality, with αCOP and Rop showing strongest lethal effects, indicating promising RNAi‐based pest control candidates.
Apurva Vikas Sabnis +8 more
wiley +1 more source
The carotenoids metabolism during tomato fruit ripening: insights into multi-level regulatory network. [PDF]
Wang J, Wu Y, Yu J.
europepmc +1 more source
Metrology for Quantum Hardware Standardization—Charting a Pathway: A Strategic Review
Advances in quantum mechanics have long underpinned metrology by enabling practical realizations of units through quantum effects. With the 2019 SI revision, traceability is anchored in defined fundamental constants, reinforcing the quantum‐mechanical basis of modern standards. In parallel, quantum technologies are transitioning from laboratory science
Nobu‐Hisa Kaneko
wiley +1 more source
De proeftuin van het RIN op landgoed Broekhuizen te Leersum [PDF]
Londo, G.
core +1 more source
Physical differentiation of adipose-derived mesenchymal stem cells into pancreatic beta-like cells using cell-imprinting and evaluation of insulin production. [PDF]
Heydari SF +3 more
europepmc +1 more source

