Results 171 to 180 of about 65,860 (259)

Enhancement of immune checkpoint inhibitor efficacy by DHX58+ SELL+ T cells in advanced gastric cancer

VIEW, EarlyView.
We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen, Youdong Liu, Hongda Pan, Tianyi Cai, Mingde Zang, Xiaowen Liu, Ziwen Long, Xin Fan, Jun Lu, Fenglin Liu   +9 more
wiley   +1 more source

A high-quality RNA-yielding protocol for laser capture microdissection of transplanted stem cell-derived Islets of Langerhans. [PDF]

Acta Diabetol
Norman D, Lau J.
europepmc   +1 more source

A high‐energy X‐ray beamline for materials science research at SPring‐8: BL15XU

Journal of Synchrotron Radiation, EarlyView.
The Japanese synchrotron facility SPring‐8 has recently relaunched BL15XU as a high‐energy X‐ray beamline for materials science research. A comprehensive description of the technical details and science cases is presented.The high‐energy X‐ray beamline BL15XU is designed to drive advancements in materials science and high‐pressure research by ...
Hiroyuki Ohsumi, Yuji Higo, Yujiro Hayashi, Jaemyung Kim, Noriyoshi Tsujino, Sho Kakizawa, Tetsuo Irifune, Tomohiro Ohuchi, Yoshio Kono, Hirokatsu Yumoto, Takahisa Koyama, Hiroshi Yamazaki, Yasunori Senba, Haruhiko Ohashi, Hidekazu Takano, Michihiro Sugahara, Taito Osaka, Makina Yabashi   +17 more
wiley   +1 more source

Ultrabroadband OCT for simultaneous visible and near-infrared light imaging of the mouse retina. [PDF]

Biomed Opt Express
Poh Chong S, Khan Mohammad A, Antypas H, Natarajan LM, Tan RJW, Török P.   +5 more
europepmc   +1 more source

Characterization of Prurigo Nodules in Adults With Moderate‐To‐Severe Atopic Dermatitis in Japan: A 2‐Year Observational Study

The Journal of Dermatology, EarlyView.
ABSTRACT Clinical phenotypes of atopic dermatitis (AD) can vary, with some individuals displaying difficult‐to‐treat prurigo nodularis‐like lesions. We aimed to assess the real‐world disease burden and treatment course of Japanese adults with AD‐associated prurigo nodules (AD‐Pn) receiving conventional AD treatments.
Yoko Kataoka, Takafumi Etoh, Hidehisa Saeki, Norito Katoh, Satoshi Teramukai, Yuki Tajima, Kwinten Bosman, Marius Ardeleanu, Kazuhiko Arima   +8 more
wiley   +1 more source

Adaptation of the invasive pest Drosophila suzukii to a specialized nutritional niche

Insect Science, EarlyView.
Unlike most Drosophila larvae that feed on spoiled food, Drosophila suzukii larvae thrive on ripening fruits and consequently face a low‐protein, high‐carbohydrate nutritional challenge. Comparisons of growth among D. suzukii, D. biarmipes, and D. melanogaster larvae across diets with varying protein‐to‐carbohydrate ratios demonstrate that D.
Yan Hou, Ying Zhen
wiley   +1 more source

Endogenous and Exogenous Small RNA Signatures as Novel Tools for Postmortem Interval Determination. [PDF]

Biomolecules
Wang Y, Li B, Wang Y, Chen Q, Wang Z, Fu G, Li S, Zhang C, Zhou Z, Cong B.   +9 more
europepmc   +1 more source

Geographical Variation in Thermal Adaptation of the Asiatic Toad (Bufo gargarizans)

Integrative Zoology, EarlyView.
Northern and southern populations of Bufo gargarizans exhibit coordinated divergence in thermal preference, resting metabolic rate, and TRPM4 temperature sensitivity along a climatic gradient. ABSTRACT Thermal adaptation in animals can manifest in multiple dimensions, yet few studies have integrated behavioral, physiological, and molecular perspectives
Longcheng Fan, Yonghua Wu
wiley   +1 more source

Correction: Evaluation of short-term hair follicle storage conditions for maintenance of RNA integrity. [PDF]

PLoS One
Harkin EE, Browne JA, Murphy BA.
europepmc   +1 more source

Effect of Kinematics and Speed on Filling Material Removal, Canal Transportation, and Apical Extrusion During Retreatment of Curved Canals

Australian Endodontic Journal, EarlyView.
ABSTRACT This study evaluated the effects of kinematics (reciprocating vs. continuous rotation) and rotational speed (350 vs. 1200 rpm) on filling removal, canal transportation, and apical extrusion during retreatment of curved root canals. Vertucci type II mesial roots of mandibular molars were prepared, filled, and scanned by micro‐computed ...
Jenny Guerrero, Josué Fernández, Flávio R. F. Alves, José C. Provenzano, Karen M. Brisson‐Suárez, Marília F. Marceliano‐Alves, Isabela N. Rôças, José F. Siqueira Jr   +7 more
wiley   +1 more source