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Oxetanes: Recent Advances in Synthesis, Reactivity and Medicinal Chemistry [PDF]
Chemical Reviews, 2016 The 4-membered oxetane ring has been increasingly exploited for its behaviors, i.e. influence on physicochemical properties as a stable motif in medicinal chemistry, and propensity to undergo ring opening reactions as a synthetic intermediate.
Bull, JA +4 more
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Efficient ring perception for the Chemistry Development Kit [PDF]
Journal of Cheminformatics, 2014 The Chemistry Development Kit (CDK) is an open source Java library for manipulating and processing chemical information. A key aspect in handling chemical structures is the determination of the chemical rings. The rings of a structure are used areas including descriptors, stereochemistry, similarity, screening and atom typing. The CDK includes multiple
May, John W, Steinbeck, Christoph
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Strain Release Chemistry of Photogenerated Small‐Ring Intermediates [PDF]
Chemistry – A European Journal, 2021 AbstractPhotochemical processes, such as isomerizations and cycloadditions, have proven to be very useful in the construction of highly strained molecular frameworks. Photoinduced ring strain enables subsequent exergonic reactions which do not require the input of additional chemical energy and provides a variety of attractive synthetic options leading
Adriana Luque, Jan Paternoga, Till Opatz
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Inorganics, 2023 We combine operando diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) with on-line mass spectrometry (MS) to study the correlation between the oxidation state of titania-supported IrO2 catalysts (IrO2@TiO2) and their catalytic activity
Phillip Timmer +3 more
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Catalytic Cascade Reactions Inspired by Polyketide Biosynthesis
CHIMIA, 2020 Aldol reactions belong to the most important methods for carbon–carbon bond formation and are also involved in one of the most astonishing biosynthetic processes: the biosynthesis of polyketides governed by an extraordinarily sophisticated enzymatic ...
Daniel Moser +6 more
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Applied Sciences, 2022 The association of cathepsin proteases in neurobiology is increasingly recognized. Our previous studies indicated that cathepsin-K-deficient (Ctsk−/−) mice have learning and memory impairments.
Denise M. T. Yu +6 more
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CHIMIA, 2010 Research projects of the Department of Chemistry, University of Basel are reviewed ranging from the synthesis of complex natural products to the development of metalorganic catalysts and organocatalysts
Karl Gademann +5 more
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The Cu(OTf)2 catalysed microwave assisted synthesis of a new scaffold, 7-aryl-7,8-dihydropyrido[4,3-c]pyridazin-5(6H)-one [PDF]
, 2014 The synthesis of novel 7-aryl-7,8-dihydropyrido[4,3-c]pyridazin-5(6H)-ones is described including a one-step Mannich-type reaction followed by intramolecular ring closure of ethyl 3-methylpyridazine-4- carboxylate and aldimines, catalysed by the Lewis ...
De Coen, Laurens +5 more
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Trace Amine-Associated Receptor 1 Trafficking to Cilia of Thyroid Epithelial Cells
Cells, 2021 Trace amine-associated receptor 1 (rodent Taar1/human TAAR1) is a G protein-coupled receptor that is mainly recognized for its functions in neuromodulation.
Maria Qatato +8 more
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