Results 1 to 10 of about 2,531,644 (304)
Strain Release Chemistry of Photogenerated Small‐Ring Intermediates [PDF]
AbstractPhotochemical processes, such as isomerizations and cycloadditions, have proven to be very useful in the construction of highly strained molecular frameworks. Photoinduced ring strain enables subsequent exergonic reactions which do not require the input of additional chemical energy and provides a variety of attractive synthetic options leading
Adriana Luque, Jan Paternoga, Till Opatz
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Put a ring on it: application of small aliphatic rings in medicinal chemistry
Aliphatic small rings including cyclopropanes, cyclobutanes, oxetanes, azetidines and bicyclo[1.1.1]pentanes have been increasingly exploited in medicinal chemistry. This review summarises judicious successful application and reported limitations of these ring systems.
Matthias R. Bauer +6 more
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Ringing medicinal chemistry: The importance of 3-membered rings in drug discovery
Scaffold-based drug design has become increasingly prominent in the pharmaceutical field due to the systematic and effective approach through which it facilitates the development of novel drugs. The identification of key scaffolds provides medicinal chemists with a fundamental framework for subsequent research.
Sahani Sandalima, Uthumange +3 more
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Can tree-ring chemistry be used to monitor atmospheric nanoparticle contamination over time?
: Industrial activities and human population growth have resulted in an unprecedented increase in the release of particulate matter (PM) into the environment.
Paula Ballikaya +2 more
semanticscholar +1 more source
We combine operando diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) with on-line mass spectrometry (MS) to study the correlation between the oxidation state of titania-supported IrO2 catalysts (IrO2@TiO2) and their catalytic activity
Phillip Timmer +3 more
doaj +1 more source
Catalytic Cascade Reactions Inspired by Polyketide Biosynthesis
Aldol reactions belong to the most important methods for carbon–carbon bond formation and are also involved in one of the most astonishing biosynthetic processes: the biosynthesis of polyketides governed by an extraordinarily sophisticated enzymatic ...
Daniel Moser +6 more
doaj +1 more source
The association of cathepsin proteases in neurobiology is increasingly recognized. Our previous studies indicated that cathepsin-K-deficient (Ctsk−/−) mice have learning and memory impairments.
Denise M. T. Yu +6 more
doaj +1 more source
Ring polymer quantization of the photon field in polariton chemistry.
We use the ring polymer (RP) representation to quantize the radiation field inside an optical cavity to investigate polariton quantum dynamics. Using a charge transfer model coupled to an optical cavity, we demonstrate that the RP quantization of the ...
Sutirtha N Chowdhury +2 more
semanticscholar +1 more source
Research projects of the Department of Chemistry, University of Basel are reviewed ranging from the synthesis of complex natural products to the development of metalorganic catalysts and organocatalysts
Karl Gademann +5 more
doaj +1 more source

