Results 31 to 40 of about 284,604 (310)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Testing annual tree-ring chemistry by X-ray fluorescence for dendroclimatic studies in high-elevation forests from the Spanish Pyrenees [PDF]

open access: yes, 2019
Climate reconstructions based on tree-ring features rely on the assumption that growth drivers are mainly meteorological variables. Consequently, annually resolved and absolutely dated temperature reconstructions in high-elevation conifer forests are ...
Sangüesa-Barreda, G   +5 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Medium ring chemistry [PDF]

open access: yes, 1968
Open ...
Brown, Edward Douglas
core  

Design of a dual sensing highly selective cyanide chemodosimeter based on pyridinium ring chemistry

open access: yes, 2011
[eng] A new chemodosimeter, Quino-P, recognizes the strongly nucleophilic cyanide by dual colorimetric and fluorescence 'off-on' signalling responses. Noteworthily, several other anions, even in significantly higher concentrations, induce no detectable ...
Frontera, A.   +4 more
core   +2 more sources

Recent Advances in Iridium-Catalyzed Asymmetric Hydrogenation: New Catalysts, Substrates and Applications in Total Synthesis

open access: yesCHIMIA, 2012
Iridium-catalyzed asymmetric hydrogenation has emerged as a highly efficient method for the synthesis of enantiomerically pure compounds. This account summarizes our recent efforts in this field.
Adnan Ganić   +3 more
doaj   +1 more source

Photochemistry Meets Porous Organic Cages

open access: yesCHIMIA, 2021
Chemistry of porous organic cages has developed in the past decade as an alternative to the wellknown nanoporous materials based on extended networks, such as metal organic frameworks (MOFs) or covalent organic frameworks (COFs).
Hsin-Hua Huang, Tomáš Šolomek
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Isolation of a 16pi-Electrons 1,4-Diphosphinine-1,4-diide with a Planar C4P2 Ring

open access: yes, 2021
Rottschäfer D, Neumann B, Stammler H-G, Andrada D, Sergeieva T, Ghadwal R. Isolation of a 16pi-Electrons 1,4-Diphosphinine-1,4-diide with a Planar C4P2 Ring. Chemistry - A European Journal.
Dennis Rottschäfer   +11 more
core   +1 more source

From lithium to sodium: cell chemistry of room temperature sodium–air and sodium–sulfur batteries

open access: yesBeilstein Journal of Nanotechnology, 2015
Research devoted to room temperature lithium–sulfur (Li/S8) and lithium–oxygen (Li/O2) batteries has significantly increased over the past ten years. The race to develop such cell systems is mainly motivated by the very high theoretical energy density ...
Philipp Adelhelm   +5 more
doaj   +1 more source

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