Results 31 to 40 of about 3,716,677 (247)

Response of Tree-Ring Density to Climate in Maine, U.S.A.

open access: yes, 1979
Cores of red spruce (Picea rubens Sarg.) from three upper-elevation sites in Maine, U.S.A., were X-rayed, and minimum and maximum wood densities as well as ring widths were mechanically recorded.
Conkey, Laura E.
core   +3 more sources

Recent Biomimetic and Organocatalytic Syntheses of ?-Tocopherol

open access: yesCHIMIA, 2010
We report here on our efforts to develop new strategies for the synthesis of ?-tocopherol, the biologically most significant member of the vitamin E family.
Antoinette Chougnet   +2 more
doaj   +1 more source

DNA Damaging Agents in Chemical Biology and Cancer

open access: yesCHIMIA, 2020
Despite their toxicity, DNA alkylating drugs remain a cornerstone of anticancer therapy. The classical thinking was that rapidly dividing tumour cells left more of its DNA in an exposed single-stranded state, making these rapidly dividing cells more ...
Basilius Sauter, Dennis Gillingham
doaj   +1 more source

Generation and ring opening of aziridine N-carbonyl radicals

open access: yes, 2005
International audienceAziridine N-carbonyl radicals, generated by irradiating the corresponding S-oxalyl xanthates, undergo ring opening to give 2-isocyanato radicals, which can be trapped by an external olefin.
Heinrich, Marcus, R.   +7 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Revised Computer Programs for Tree-Ring Research

open access: yes, 1979
Three computer programs that are basic to the processing and development of tree -ring chronologies are now available. They were designed to refine and replace older programs that were previously furnished by the laboratory.
Graybill, Donald A.
core   +4 more sources

From lithium to sodium: cell chemistry of room temperature sodium–air and sodium–sulfur batteries

open access: yesBeilstein Journal of Nanotechnology, 2015
Research devoted to room temperature lithium–sulfur (Li/S8) and lithium–oxygen (Li/O2) batteries has significantly increased over the past ten years. The race to develop such cell systems is mainly motivated by the very high theoretical energy density ...
Philipp Adelhelm   +5 more
doaj   +1 more source

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