Results 21 to 30 of about 851,331 (355)
Catalytic Cascade Reactions Inspired by Polyketide Biosynthesis
Aldol reactions belong to the most important methods for carbon–carbon bond formation and are also involved in one of the most astonishing biosynthetic processes: the biosynthesis of polyketides governed by an extraordinarily sophisticated enzymatic ...
Daniel Moser+6 more
doaj +1 more source
The association of cathepsin proteases in neurobiology is increasingly recognized. Our previous studies indicated that cathepsin-K-deficient (Ctsk−/−) mice have learning and memory impairments.
Denise M. T. Yu+6 more
doaj +1 more source
XXXI.—Contribution to the chemistry of “Fairy Rings.” [PDF]
n ...
Lawes, J. B.+2 more
openaire +2 more sources
Put a ring on it: application of small aliphatic rings in medicinal chemistry
Aliphatic small rings including cyclopropanes, cyclobutanes, oxetanes, azetidines and bicyclo[1.1.1]pentanes have been increasingly exploited in medicinal chemistry. This review summarises judicious successful application and reported limitations of these ring systems.
Matthias R. Bauer+6 more
openaire +4 more sources
Chemical footprints of giant planet formation. Role of planet accretion in shaping the C/O ratio of protoplanetary disks [PDF]
Protoplanetary disks, the birthplaces of planets, commonly feature bright rings and dark gaps in both continuum and line emission maps. Accreting planets are interacting with the disk, not only through gravity, but also by changing the local irradiation and elemental abundances, which are essential ingredients for disk chemistry.
arxiv +1 more source
A Unified Mechanism on the Formation of Acenes, Helicenes, and Phenacenes in the Gas Phase. [PDF]
A unified low-temperature reaction mechanism on the formation of acenes, phenacenes, and helicenes-polycyclic aromatic hydrocarbons (PAHs) that are distinct via the linear, zigzag, and ortho-condensed arrangements of fused benzene rings-is revealed. This
Ablikim, Utuq+8 more
core +1 more source
Conformer-specific Chemistry Imaged in Real Space and Time [PDF]
Conformational isomers or conformers of molecules play a decisive role in chemistry and biology. However, experimental methods to investigate chemical reaction dynamics are typically not conformer-sensitive. Here, we report on a gas-phase megaelectronvolt ultrafast electron diffraction investigation of {\alpha}-phellandrene undergoing an electrocyclic ...
arxiv +1 more source
Research projects of the Department of Chemistry, University of Basel are reviewed ranging from the synthesis of complex natural products to the development of metalorganic catalysts and organocatalysts
Karl Gademann+5 more
doaj +1 more source
On-Surface Synthesis of Silole and Disilacyclooctaene Derivatives [PDF]
Sila-cyclic rings are a class of organosilicon cyclic compounds and have abundant application in organic chemistry and materials science. However, it is still challenging to synthesize compounds with sila-cyclic rings in solution chemistry due to their low solubility and high reactivity.
arxiv +1 more source
Oxetanes: Recent Advances in Synthesis, Reactivity and Medicinal Chemistry [PDF]
The 4-membered oxetane ring has been increasingly exploited for its behaviors, i.e. influence on physicochemical properties as a stable motif in medicinal chemistry, and propensity to undergo ring opening reactions as a synthetic intermediate.
Bull, JA+4 more
core +1 more source