Results 251 to 260 of about 830,676 (348)
DMF/DMSO-catalyzed selective ring-opening polymerization of salicylate cyclic esters. [PDF]
Yao G +7 more
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Force-Accelerated Ring Opening of Episulfide by Pulsed Ultrasonication. [PDF]
Ko CH +6 more
europepmc +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Design and synthesis of a novel chiral triptycene-based imine ligand for enantioselective epoxide ring-opening reactions. [PDF]
Guleria M, Kaur M, Tagra D, Agarwal J.
europepmc +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
One Step Block-like Copolymers from an Upcycled Monomer Using Ring-Opening Metathesis Polymerization. [PDF]
Foster JC +5 more
europepmc +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Molecular dynamics of bicyclo[2.2.0]hex-2-ene ring opening and its polar derivative: allowed <i>vs.</i> forbidden pathways. [PDF]
Qin Z, Zhou Q, Wu RK, Houk KN.
europepmc +1 more source

