Results 1 to 10 of about 8,858 (221)
Preface to “Aziridine Chemistry” [PDF]
Molecules, 2021 Aziridine is a nitrogen-containing three-membered ring with similar ring strain energy as other three-membered ring compounds, including cyclopropane and oxirane [...]
Hyun-Joon Ha
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Alkylative Aziridine Ring-Opening Reactions
Molecules, 2021 In this study, the highly strained three-membered aziridine ring was successfully activated as the aziridinium ion by alkylation of the ring nitrogen with a methyl, ethyl or allyl group, which was followed by ring opening with external nucleophiles such ...
Jieun Choi, Taehwan Yu, Hyun-Joon Ha
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Regioselective ring opening of aziridine for synthesizing azaheterocycle
Frontiers in Chemistry, 2023 Aziridine had different regioselective ring openings depending on the functional group of its alkyl substituent. In the case of the alkyl group bearing γ-ketone at the C2 substituent of aziridine, the ring opening by the hydroxy nucleophile from H2O ...
Nikhil Srivastava, Hyun-Joon Ha
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Pd-Catalyzed Cycloaddition of Bicyclic Aziridine with Isocyanates
Medical Sciences Forum, 2022 Nitrogen-containing heterocycles can have several applications in the pharmaceutical industry since they contain a wide spectrum of biological activities. Imidazolidinones have shown activity against leukemia, lung cancer, and metabolic disorders.
Mariana Crespo Monteiro +2 more
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Frontiers in Chemistry, 2023 Herein we report a copper-catalyzed synthesis of imidazolidine by employing the reaction of aziridine with imine. The reaction smoothly provided a diverse range of 2-substituted imidazolidines with high compatibility with various functional groups ...
Kota Hashimoto +4 more
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The Synthesis of (2R)-Aziridine-2-carboxylic Acid Containing Dipeptides
Acta Chimica Slovenica, 2022 Optimized conditions for the synthesis of fully deprotected (2R)-aziridine containing dipeptides are described. Preparation of fully protected N- and C- terminal aziridine containing dipeptides was found to be straightforward and high yielding for the ...
Samo Kuzmič, Martina Hrast, Rok Frlan
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Substituted Aziridines by Lithiation—Electrophile Trapping of Terminal Aziridines. [PDF]
ChemInform, 2005 AbstractFor Abstract see ChemInform Abstract in Full Text.
Hodgson, D, Humphreys, P, Ward, J
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Molecules, 2022 Endophytes, being the co-evolution partners of green host plants, are factories of pharmaceutically valuable novel natural products. Cochliobolus sp. APS1, an endophyte of Andrographis paniculata (Green Chiretta), produces a plethora of natural bioactive
Hiran Kanti Santra +2 more
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Recent Developments in Stereoselective Reactions of Sulfonium Ylides
Organics, 2022 This review describes advances in the literature since the mid-1990s in the area of reactions of sulfonium ylide chemistry, with particular attention paid to stereoselective examples.
Mukulesh Mondal +4 more
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Synthetic Applications of Aziridinium Ions
Molecules, 2021 Nonactivated aziridine with an electron-donating group at the ring nitrogen should be activated to an aziridinium ion prior to being converted to cyclic and acyclic nitrogen-containing molecules.
Jala Ranjith, Hyun-Joon Ha
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