Electrochemistry of potential bioreductive alkylating quinones : Part 2. Electrochemical properties of 2,5-bis(1-aziridinyl)-3,6-bis(ethoxycarbonylamino)-1,4-benzoquinone and some model compounds [PDF]
, 1990 The reduction mechanism of 2,5-bis(1-aziridinyl)-3,6-bis(ethoxycarbonylamino)-1,4-benzoquinone (Diaziquone, AZQ) and several model compounds of the mono- and bis(1-aziridinyl)quinone type at the dropping mercury electrode in aqueous solutions was studied.
Blauw, J.S. +6 more
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Synthesis and reactivity of 4-(trifluoromethyl)azetidin-2-ones [PDF]
, 2018 Because of the beneficial effect of a trifluoromethyl group on the biological properties of bioactive compounds on the one hand and the versatile synthetic potential of beta-lactams on the other hand, 4-CF3-beta-lactams comprises interesting entities for
D'hooghe, Matthias +2 more
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First-Principles Study of Chemisorption of Oxygen and Aziridine on Graphitic Nanostructures [PDF]
, 2009 Using ab initio plane wave pseudopotential calculations, we study the energetics and structure of adsorbed linear arrays of oxygen and aziridine on carbon nanotubes, graphitic ribbons, and graphene sheets.
Giapis, Konstantinos P., Kutana, Alex
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Atom Economical Multi-Substituted Pyrrole Synthesis from Aziridine
Molecules, 2022 Multi-substituted pyrroles are synthesized from regiospecific aziridine ring-opening and subsequent intramolecular cyclization with a carbonyl group at the γ-position in the presence of Lewis acid or protic acid.
Lingamurthy Macha +3 more
doaj +1 more source
Investigation of macrocyclisation routes to 1,4,7-triazacyclononanes : efficient syntheses from 1,2-ditosylamides [PDF]
, 2008 Two routes to the synthesis of a cyclohexyl-fused 1,4,7-triazacyclononane involving macrocyclisations of tosamides have been investigated. In the first approach, using a classic Richman-Atkins-type cyclisation of a cyclohexyl-substituted 1,4,7 ...
Gibson, C.L. +6 more
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MethodsX, 2019 A rapid HILIC-MS method was developed for measuring the genotoxic impurities aziridine and 2-chloroethylamine. Sample preparation was simple and direct without requiring derivatization.
Jonathan G. Shackman
doaj +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 In this study, we report a series of newly synthesised sulphonamides of aziridine-2-carboxylic acid (Az-COOH) ester and amide analogues as potent protein disulphide isomerase (PDI, EC 5.3.4.1) inhibitors.
D. Zelencova-Gopejenko +12 more
doaj +1 more source
Microwave-assisted regioselective ring opening of non-activated aziridines by lithium aluminium hydride [PDF]
, 2010 A new synthetic protocol for the LiAlH4-promoted reduction of non-activated aziridines under microwave conditions was developed. Thus, ring opening of 2-(acetoxymethyl)aziridines provided the corresponding beta-amino alcohols, which were then used as ...
D'hooghe, Matthias +2 more
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Chemoenzymatic Synthesis of Triazololactams Structurally Related to Pancratistatin [PDF]
, 2017 Four tricyclic lactams that structurally resemble alkaloids with the pancratistatin skeleton were synthetized from bromobenzene by a chemoenzymatic strategy.
Bastida +48 more
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Concise Synthesis of (+)-allo-Kainic Acid via MgI2-Mediated Tandem Aziridine Ring Opening-Formal [3+2] Cycloaddition [PDF]
, 2013 3-Methyl vinyl aziridine undergoes a mild MgI2-promoted S(N)2' ring opening and concomitant cyclization with fumarate Michael acceptors to give trisubstituted pyrrolidines. The process is efficient and highly diastereoselective. This methodology has been
Aggarwal, Varinder K. +3 more
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