Results 11 to 20 of about 8,858 (221)

Mechanistic Insights into Lewis Acid-Catalyzed Formal [3 + 2] Cycloadditions of Aziridines: A Molecular Electron Density Theory Study [PDF]

Molecules
The Lewis acid (LA)-promoted formal [3 + 2] cycloaddition (32CA) reaction of 2-phenyl-1-tosylaziridine (2PTA) with ketone has been studied within the framework of Molecular Electron Density Theory (MEDT) at the ωB97X-D/6-311G(d,p) computational level in ...
Luis R. Domingo, Patricia Pérez, Maria José Aurell   +2 more
doaj   +2 more sources

Copper-catalyzed heterocyclic recombination of aziridine and diazetidine for the synthesis of imidazolidine [PDF]

, 2023
The discovery of new catalytic applications for metals remains an important goal in organic synthesis. If a catalyst has multiple functions, such as inducing bond cleavage and formation, it can streamline multi-step transformations. Herein, we report the
Satoshi, Matsubara, Daisuke, Tanaka, Kei, Murakami, Hiroki, Kadowaki, Daiki, Higuchi   +4 more
core   +2 more sources

Aziridine Carboxylates, Carboxamides and Lactones: New Methods for Their Preparation and Their Transformation into α- and β-Amino Acid Derivatives

Molecules, 2000
The preparation of a variety of novel aziridine-γ-lactones (3) from carbohydrates is described. In contrast to aziridine-2-carboxylates, the lactones react regiospecifically at C-2 with soft nucleophiles to provide optically pure substituted β ...
Robert H. Dodd
doaj   +1 more source

[(2R,3R)-3-(4-Nitrophenyl)aziridin-2-yl]methanol monohydrate

Acta Crystallographica Section E, 2013
The title monohydrate, C9H10N2O3·H2O, contains an aziridine ring including two contiguous stereocenters, both of which exhibit an R configuration. The methylhydroxy and nitrophenyl groups are cis-disposed about the aziridine ring.
V. Gaumet, C. Denis, F. Leal, M. Madesclaire, V.P. Zaitsev   +4 more
doaj   +1 more source

(2S)-2-[(2S*,5R*,6R*)-5,6-Dimethoxy-5,6-dimethyl-1,4-dioxan-2-yl]-1-[(S)-1,1-dimethylethylsulfonyl]aziridine

Acta Crystallographica Section E, 2010
The reaction of a sulfur ylide with a chiral non-racemic sulfinyl imine afforded the desired aziridine in excellent yield and subsequent oxidation of the sulfinyl moiety dissolved in anhydrous dichloromethane using a 75% aqueous solution of 3 ...
David C. Forbes, Sampada V. Bettigeri, William Lewis, Toni Moragas Solà, Robert A. Stockman   +4 more
doaj   +1 more source

Microwave Heating Promotes the S-Alkylation of Aziridine Catalyzed by Molecular Sieves: A Post-Synthetic Approach to Lanthionine-Containing Peptides

Molecules, 2021
Aziridine derivatives involved in nucleophilic ring-opening reactions have attracted great interest, since they allow the preparation of biologically active molecules.
Valentina Verdoliva, Giuseppe Digilio, Michele Saviano, Stefania De Luca   +3 more
doaj   +1 more source

Aziridine-Capped Poly(ethylene glycol) Brush Copolymers with Tunable Architecture as Versatile Cross-Linkers for Adhesives

, 2022
Controlling adhesive and cohesive properties in a refined manner is paramount to developing high-performance adhesives. Therefore, developing and implementing cross-linkers have become a major focus in adhesive research, but most conventional cross ...
Chaenyung Cha, Jisu Hong, Min Sang Kwon, Yonghwan Kwon, Jisu Hong (1521565), Chaenyung Cha (1305165), Yonghwan Kwon (7280348), Min Sang Kwon (1359204)   +7 more
core   +1 more source

Efficient synthesis of ethyl 2-(oxazolin-2-yl)alkanoates via ethoxycarbonylketene-induced electrophilic ring expansion of aziridines

Beilstein Journal of Organic Chemistry, 2022
Alkyl 2-diazo-3-oxoalkanoates generate alkoxycarbonylketenes, which undergo an electrophilic ring expansion with aziridines to afford alkyl 2-(oxazolin-2-yl)alkanoates in good to excellent yields under microwave heating.
Yelong Lei, Jiaxi Xu
doaj   +1 more source

Synthesis and Density Functional Theory Studies of Azirinyl and Oxiranyl Functionalized Isoindigo and (3Z,3’Z)-3,3’-(ethane-1,2-diylidene)bis(indolin-2-one) Derivatives

Molecules, 2019
The design and synthesis of functionalized isoindigo compounds by reaction of isoindigo with (S)-glycidyl tosylate, epibromohydrin, 2-(bromomethyl)-1-(arylsulfonyl)aziridine, and 2-(bromomethyl)-1-(alkylsulfonyl)aziridine in the presence of MeONa proceed
Gholamhossein Khalili, Patrick M. McCosker, Timothy Clark, Paul A. Keller   +3 more
doaj   +1 more source

Modular and Stereoselective Synthesis of Cyclobutane β‐Amino Alcohols

Angewandte Chemie, EarlyView.
Late‐stage functionalization and photoisomerization of 1,2‐azaborine leads to a general strategy for the synthesis of diversely substituted cyclobutane β‐amino alcohols. The relative stereochemistry of the resulting products is unambiguously defined by the stereospecific and stereoselective nature of the photoisomerization‐hydrogenation‐oxidation ...
Xinyu Yang, Tomoya Ozaki, Bo Li, Shih‐Yuan Liu   +3 more
wiley   +2 more sources