Results 51 to 60 of about 4,312 (262)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Stability analysis of deepwater compliant vertical access riser about parametric excitation
International Journal of Naval Architecture and Ocean Engineering, 2019 If heave motion in the platform causes horizontal parametric vibration of a Compliant Vertical Access Riser (CVAR), the riser may become unstable. A combination of riser parameters lies in the unstable region aggravates vibrational damage to the riser ...
Min Lou +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Experimental Study on Two-phase Flow and Vibration Characteristics of Marine Riser
Shiyou jixie, 2016 In order to identify flow patterns that may occur in the marine riser system and study the dynamic response of the riser under different flow patterns,two-phase flow pressure fluctuations in the riser and resulting riser vibration displacement were ...
Liu Chang +4 more
doaj
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Impact Analysis of Modal Parameters of Marine Riser Based on Differential Transformation Method
Shiyou jixie, 2018 To study the change rule of modal parameters (natural frequency and vibration mode) of marine risers influenced by structural parameters (riser length and bending stiffness), axial tension (constant tension and variable tension), elastic restraint ...
Chen Wenli +3 more
doaj
Chemical Engineering Transactions, 2015 One of the main problems associated with reactors in commercial Residue Fluidized Catalytic Cracking (RFCC) process in refinery plant is that each of six outlets of the riser has different particle mass flow rates.
H. Cho +5 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source