Results 71 to 80 of about 1,047 (208)

Numerical simulation research on the influence of steel ingot of 76 tons and 8 corners with hollow riser

open access: yesMetalurgija, 2019
The effect of a hollow riser on the upper heat dissipation of 76 tons and 8 corners ingots is studied by numerical simulation in this paper. Through the simulation of the heat transfer of the traditional riser, the 1 gap riser and the 2 gaps riser ingot,
G. W. Ao   +3 more
doaj  

Severe Slugging in Air-Water Hybrid Riser System

open access: yesAdvances in Mechanical Engineering, 2014
In the subsea pipeline gathering system, severe slugging flow is prone to occur. Severe slugging flow brings major threat to production and flow assurance in oil and gas industry due to periodical pressure oscillation and large liquid volume.
Jing Gong   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dynamic Characteristics Analysis of Deepwater Riser under Soft Suspension Evacuation Conditions

open access: yesShiyou jixie, 2022
Aiming at the problem of vibration failure of deepwater riser under the condition of soft suspension emergency evacuation, combined with the Hamiltonian variational and virtual work principle, the finite element method was used to build a 3D nonlinear ...
Liu Jun, Wang Pucheng, Guo Xiaoqiang
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

ANALYSIS ON CALCULATION METHOD OF RISER IN SHELL AND TUBE WASTE HEAT BOILER

open access: yesJixie qiangdu, 2018
Water recycle system is formed by shell and tube waste heat boiler body,drum,down comer and riser. The riser connects boiler body and drum. When the production of steam is less account in the system,the riser supports the whole mass of boiler drum and ...
HU Tao, ZHANG Fan
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Testing on Dynamic Load of 200K Wire Rope Type Riser Tensioner

open access: yesShiyou jixie, 2017
In order to address the difficult of offshore drilling riser tensioner testing and to verify the reliability of domestic riser tensioner, the testing of riser tensioner has been carried out. Analyses on the speed and tension force of the wire rope of the
Zhou Tianming   +6 more
doaj  

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