Results 201 to 210 of about 3,217,510 (267)

The Tyrer-Cuzick risk model: Is it effective for all races? [PDF]

Clin Imaging
Patil S, Mehran NA, Erblich J, Montgomery GH, Schnur JB, Margolies LR.   +5 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Identification and Validation of a Two-Gene NK Cell-Related Risk Model for COPD: Integration of Single-Cell and Bulk RNA-Seq Analysis. [PDF]

Int J Chron Obstruct Pulmon Dis
Fu X, Dong J, Yang J, Zhang X, Cai S, Zhang Y, Lv S, Zhang M.   +7 more
europepmc   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Testing Transferability of a Mortality Risk Model for Interhospital Transfer Using Real-World Electronic Health Records: External Validation and Model Enhancement. [PDF]

Crit Care Explor
Hadler RA, Lakamana SK, Moorman T, Bozkurt S.   +3 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

A prognostic risk model based on programmed cell death genes for breast cancer and its potential clinical application. [PDF]

Medicine (Baltimore)
Zhang Z, Yang X, Tang J, Cai L, Feng J.
europepmc   +1 more source

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

FEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller, Jana Bleher, Birgit Weinberger, Lourdes Rocamora‐Reverte   +3 more
wiley   +1 more source

A next-generation prediction risk model for acute myocardial infarction: Derivation and validation in a multi-centre cohort. [PDF]

Int J Cardiol Cardiovasc Risk Prev
Amorocho-Morales JD, Guevara SP, Quintero-Muñoz E, Dimas G, Correa-Morales JE.   +4 more
europepmc   +1 more source