Results 111 to 120 of about 3,058 (214)

Didymin Alleviates Hepatic Fibrosis Through Inhibiting ERK and PI3K/Akt Pathways via Regulation of Raf Kinase Inhibitor Protein

Cellular Physiology and Biochemistry, 2016
Background: Didymin has been reported to have anti-cancer potential. However, the effect of didymin on liver fibrosis remains illdefined. Methods: Hepatic fibrosis was induced by CCl4 in rats.
Xing Lin, Faicheng Bai, Jinlan Nie, Shengjuan Lu, Chunyuang Lu, Xunshuai Zhu, Jinbin Wei, Zhongpeng Lu, Quanfang Huang   +8 more
doaj   +1 more source

RKIP regulates the ERK/MAPK signaling pathway to improve neuroinflammatory injury in male rats with ischemic stroke

Journal of Stroke and Cerebrovascular Diseases
Background: To explore the mechanism by which RAF kinase inhibitory protein (RKIP) alleviates neuroinflammatory damage in male rats with ischemic stroke (IS). Methods: Male rats were subjected to middle cerebral artery occlusion (MCAO) to establish an IS
Rui Mao, Xin Tan, Rong Li, Zhiyong Yang, Hua Liu   +4 more
doaj   +1 more source

Role of RKIP protein in the modulation of lung cancer cell metabolism

, 2021
Os tumores sólidos são caracterizados por uma dependência exacerbada de glucose, sendo a reprogramação metabólica das células tumorais considerada um hallmark do cancro. Hoje é sabido que esta reprogramação em tumores é frequentemente controlada e induzida pela ativação oncogénica de vias de sinalização celular.
openaire   +1 more source

Raf kinase inhibitor protein1 is a myogenic inhibitor with conserved function in avians and mammals [PDF]

, 2016
Abu-Elmagd, Al-Mulla, Al-Mulla, Anakwe, Bakkar, Bennett, Bentzinger, Bernardi, Chatterjee, Cho, Coolican, Cossu, Deiss, Eves, Garcia, Gredinger, Guttridge, Guttridge, Kami, Langen, Li, Lorenz, MacDonald, Nieto, Rao, Sun, Sun, Tanaka, Theroux, Trenerry, Velica, Wang, Yang, Yang, Yeung, Yeung, Yokoyama   +36 more
core   +2 more sources

Petri nets for systems and synthetic biology [PDF]

, 2008
We give a description of a Petri net-based framework for modelling and analysing biochemical pathways, which uni¯es the qualita- tive, stochastic and continuous paradigms.
Donaldson, R, Gilbert, D, Heiner, M
core   +1 more source

Mrpl35, A Mitospecific Component of Mitoribosomes, Plays A Key Role in Cytochrome \u3cem\u3eC\u3c/em\u3e Oxidase Assembly [PDF]

, 2017
Mitoribosomes perform the synthesis of the core components of the oxidative phosphorylation (OXPHOS) system encoded by the mitochondrial genome.
Box, Jodie M, Kaur, Jasvinder, Stuart, Rosemary A.   +2 more
core   +1 more source

A systems-level analysis of the mutually antagonistic roles of RKIP and BACH1 in dynamics of cancer cell plasticity. [PDF]

J R Soc Interface, 2023
Shyam S, Ramu S, Sehgal M, Jolly MK.
europepmc   +1 more source

ESPRESSIONE DI VEGF, HSP90 E Bip/GRP78 E RICORRENZA DI CARCINOMA EPATOCELLULARE DOPO TRAPIANTO DI FEGATO [PDF]

Background and aims Liver transplantation (LT) for hepatocellular carcinoma (HCC) is a satisfactory therapeutic choice in patients with “early HCC” selected according to Milan criteria. However, the risk of HCC recurrence after LT is about 7-10% at five
CORSALE, Sveva
core  

Raf kinase inhibitor protein combined with phosphorylated extracellular signal-regulated kinase offers valuable prognosis in gastrointestinal stromal tumor. [PDF]

World J Gastroenterol, 2023
Qu WZ, Wang L, Chen JJ, Wang Y.
europepmc   +1 more source

Metastasis suppressor genes and their role in the tumor microenvironment. [PDF]

Cancer Metastasis Rev, 2023
Megino-Luque C, Bravo-Cordero JJ.
europepmc   +1 more source