Results 161 to 170 of about 3,058 (214)

Regulation of PD-L1 Expression by YY1 in Cancer: Therapeutic Efficacy of Targeting YY1. [PDF]

open access: yesCancers (Basel)
Dillen A   +5 more
europepmc   +1 more source

Resveratrol binds and activates RKIP protein in colorectal cancer

Amino Acids, 2020
Raf-1 kinase inhibitory protein (RKIP) acts as a tumor cell metastasis suppressor and prognostic indicator for survival in various cancers. Its use is predicted to improve therapy for various malignancies, including colorectal cancer (CRC). RKIP, frequently denoted as phosphatidylethanolamine-binding protein 1, is expressed in all normal mammalian ...
Begum Dariya   +5 more
openaire   +2 more sources

Raf kinase inhibitor protein (RKIP) and phospho-RKIP expression in melanomas

Acta Histochemica, 2013
Melanoma, a cancer notorious for its high potential to metastasize, arises from melanocytes, cells dedicated to melanin production and located in the basal layer of the epidermis. Raf-1 kinase inhibitor protein (RKIP) is an inhibitory molecule that down-regulates the effects of the Ras/Raf/MEK/ERK signaling pathway. The aim of this study was to examine
CARDILE, Venera   +6 more
openaire   +3 more sources

Raf kinase inhibitor protein (RKIP) in cancer

Cancer and Metastasis Reviews, 2012
Raf kinase inhibitory protein (RKIP) was initially identified as phosphatidylethanolamine binding protein in bovine brain. It was later identified as a protein that inhibits Raf kinase activation of MEK. Further exploration has revealed that RKIP modulates several other signaling pathways including NF-κB and G-protein signaling.
June, Escara-Wilke   +2 more
openaire   +2 more sources

RKIP: Much more than Raf Kinase inhibitory protein

Journal of Cellular Physiology, 2013
AbstractFrom its discovery as a phosphatidylethanolamine‐binding protein in bovine brain to its designation as a physiological inhibitor of Raf kinase protein, RKIP has emerged as a critical molecule for maintaining subdued, well‐orchestrated cellular responses to stimuli.
Fahd, Al-Mulla   +3 more
openaire   +2 more sources

Unique Pattern of Raf-1 Kinase Inhibitory Protein (RKIP) Expression in Multiple Myeloma (MM): RKIP Overexpression and RKIP Phosphorylation Is Common in MM Tumor Cells

Blood, 2008
Abstract Objective and Rationale Raf-1 kinase inhibitor protein (RKIP) is a modulator of cell signaling and survival that functions as an endogenous inhibitor of multiple kinases, including kinases involved in the Raf-1/MEK/ERK and NF-kB pathways.
Benjamin Bonavida   +8 more
openaire   +1 more source

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