Results 71 to 80 of about 3,058 (214)
Journal of Chemometrics, Volume 39, Issue 2, February 2025.ABSTRACT The analysis of single cell multi‐omics data is a complex task, and many explorative data analysis methods are being used to draw information from such data. This paper compares several of these methods to visualize the output of a mechanistic model under various simulated conditions.
J. A. Westerhuis +5 more
wiley +1 more source
Gynecological Endocrinology, 2022 Background NeiyiKangfu tablets (NYKF) are widely used clinically for the treatment of endometriosis (EMS), whose mechanism of action has been extensively studied.
Yi Wen +7 more
doaj +1 more source
E-cadherin expression is associated with somatostatin analogue response in acromegaly [PDF]
, 2018 Acromegaly is a rare disease resulting from hypersecretion of growth hormone (GH) and insulin‐like growth factor 1 (IGF1) typically caused by pituitary adenomas, which is associated with increased mortality and morbidity. Somatostatin analogues (SSAs)
Cano, David A. +10 more
core +1 more source
Food Science &Nutrition, Volume 12, Issue 12, Page 9951-9973, December 2024.This study discussed the therapeutic capacity of various polyphenols, terpenoids, and alkaloids on CRC via the PI3K/Akt/mTOR pathway. Each bioactive component causes various physiological processes, such as triggering free radical production, disruption of mitochondrial membrane potential, cell cycle arrest, inhibition of CRC stem cell migration ...
Kübra Demir +4 more
wiley +1 more source
The Expression and Significance of RKIP in Lung Squamous Cell Carcinoma Tissues
Chinese Journal of Lung Cancer, 2011 Background and objective Raf kinase inhibitory protein (RKIP) belongs to the phosphatidylethanolamine binding protein (PEBP) family. RKIP is an endogenous inhibitor of the Raf-1-MEK1/2-ERK1/2 signaling pathway, NFkappaB signaling pathway and G protein ...
Haiyuan XU +6 more
doaj
Raf Kinase Inhibitory Protein Down-Expression Exacerbates Hepatic Fibrosis In Vivo and In Vitro
Cellular Physiology and Biochemistry, 2016 Background/Aims: Raf kinase inhibitory protein (RKIP) is closely associated with numerous tumors and participates in their development through regulating the growth, apoptosis, invasion and metastasis of tumor cells.
Quanfang Huang +8 more
doaj +1 more source
Advanced Science, Volume 11, Issue 41, November 6, 2024.Understanding the mechanism of cancer‐adipose conversion (CAC) is a critical and complex challenge in cancer treatment. A systems biology approach combining molecular network modeling and experiments is proposed based on energy landscape theory, which provides an important way to identify optimal drug combinations driving CAC.
Zihao Chen +4 more
wiley +1 more source
Influence of RKIP Protein Complexes Concentrations on the Quasi-Stationary Behaviour of the MEK/ERK Signal Transduction Pathway [PDF]
Bioautomation, 2007 It is considered the quasi-stationary approximation of a dynamic model, representing a positive feedback mechanism in the MEK/ERK signaling pathway mediated by RKIP.
Petrov V., Nikolova E.
doaj
The Plant Journal, Volume 120, Issue 4, Page 1410-1420, November 2024.SUMMARY Genes of the family PHOSPHATIDYLETHANOLAMINE‐BINDING PROTEINS (PEBP) have been intensely studied in plants for their role in cell (re)programming and meristem differentiation. Recently, sporadic reports of the presence of a new type of PEBP in plants became available, highly similar to the YY‐PEBPs of prokaryotes.
Francesca Bellinazzo +10 more
wiley +1 more source
RKIP as an Inflammatory and Immune System Modulator: Implications in Cancer
Biomolecules, 2019 Raf kinase inhibitor protein (RKIP), an important modulator of intracellular signalling pathways, is commonly downregulated in multiple cancers. This reduction, or loss of expression, is correlated not only with the presence of metastasis, contributing ...
Maria Gabriela-Freitas +4 more
doaj +1 more source