Results 21 to 30 of about 150,391 (120)

Automated Input Variable Selection for Analog Methods Using Genetic Algorithms

Water Resources Research, Volume 60, Issue 4, April 2024.
Abstract Analog methods (AMs) have long been used for precipitation prediction and climate studies. However, they rely on manual selections of parameters, such as predictor variables and analogy criteria. Previous work showed the potential of genetic algorithms (GAs) to optimize most of the AM parameters.
P. Horton, O. Martius, S. L. Grimm
wiley   +1 more source

A potential herbal component for the future treatment of fatty liver disease: Geniposide from gardenia

Frontiers in Pharmacology
Nonalcoholic fatty liver disease (NAFLD) is a multisystemic metabolic disease whose global incidence is increasing annually; the currently available treatment options are limited to lifestyle alterations and symptomatic treatments, such as ...
Qinyao Zhang, Ziyan Li, Lina Wang
doaj   +1 more source

A Study on the Potential of Valorizing Sargassum latifolium into Biofuels and Sustainable Value‐Added Products

International Journal of Biomaterials, Volume 2024, Issue 1, 2024.
To increase the limited commercial utility and lessen the negative environmental effects of the massive growth of brown macroalgae, this work illustrates the feasibility of valorizing the invasively proliferated Sargassum latifolium into different value‐added products.
Nour Sh. El-Gendy, Mohamed Hosny, Abdallah R. Ismail, Ahmed A. Radwan, Basma A. Ali, Hager R. Ali, Radwa A. El-Salamony, Khaled M. Abdelsalam, Manal Mubarak, Kaliannan Durairaj   +9 more
wiley   +1 more source

Efficacy of Tripterygium glycosides in immune-mediated kidney diseases as a immunomodulation drug in combination with conventional immunosuppressive agents: a systematic review and meta-analysis of randomized controlled trials

Frontiers in Pharmacology
BackgroundImmune-mediated kidney diseases involve the immune system attacking the kidneys, resulting in damage and dysfunction. Tripterygium glycosides (TG) are known for their strong immunosuppressive and anti-inflammatory effects and are commonly used ...
Yaotan Li, Yaotan Li, Jinyi Hou, Jinyi Hou, Xiaochang Wu, Xiaochang Wu, Chang Liu, Mengqi Zhou, Shijia Lin, Weijing Liu, Weijing Liu, Yaoxian Wang, Yaoxian Wang, Huijuan Zheng, Huijuan Zheng   +14 more
doaj   +1 more source

Enhanced Artificial Rabbits Algorithm Integrating Equilibrium Pool to Support PV Power Estimation via Module Parameter Identification

International Journal of Energy Research, Volume 2024, Issue 1, 2024.
This paper proposes a novel innovative version of enhanced artificial rabbit optimization (EARO) algorithm integrating an equilibrium pool (EP) that consists of the best solutions. Furthermore, the detour foraging and hiding mechanisms are modified to amplify the search capability.
Idris H. Smaili, Ghareeb Moustafa, Dhaifallah R. Almalawi, Ahmed Ginidi, Abdullah M. Shaheen, Hany S. E. Mansour, Ahmed Fathy   +6 more
wiley   +1 more source

Unlocking ginsenosides’ therapeutic power with polymer-based delivery systems: current applications and future perspectives

Frontiers in Pharmacology
Ginsenosides, as the main active ingredient of Panax plants, have been found to have extensive pharmacological activity and clinical therapeutic potential in recent years. However, its inherent physical and chemical properties such as poor solubility and
Xiaomin Yu, Xiaomin Yu, Yun Lu, Yun Lu, Jiajing Chen, Yuqian Deng, Huan Liu   +6 more
doaj   +1 more source

Adverse effects of antiseizure medications: a review of the impact of pharmacogenetics and drugs interactions in clinical practice

Frontiers in Pharmacology
Epilepsy is a chronic and debilitating neurological disorder characterized by the occurrence of spontaneous and recurrent seizures. Despite the availability of several antiseizure medications (ASMs), people with epilepsy often experience drug resistance ...
Michela De Bellis, Giuseppe d’Orsi, Egidio Maria Rubino, Claudia Arigliano, Massimo Carella, Vittorio Sciruicchio, Antonella Liantonio, Annamaria De Luca, Paola Imbrici   +8 more
doaj   +1 more source

A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma

Frontiers in Pharmacology
IntroductionHepatocellular carcinoma (HCC) ranks among the three most prevalent cancer-related diseases in terms of incidence. Hence, exploring drugs for HCC therapy is of great significance.
Yue Fu, Yue Fu, Weiyue Fang, Fuqiang Qiu, Juncai Lai, Yangjin Xu, Bin Chen, Yang Li, Xiaohui Zhu, Xiaohui Zhu   +9 more
doaj   +1 more source

2-Dodecyl-6-methoxycyclohexa-2,5-dien-1,4-dione alleviates liver fibrosis and improves intestinal flora and bile acid metabolism

Frontiers in Pharmacology
BackgroundThe bioactive compound 2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione (DMDD), derived from the horn root of star fruit, exhibits therapeutic promise through its modulation of the TGF-β1 pathway and regulation of bile acids.MethodsIn this ...
Yongfei He, Thi Thai Hoa Pham, Junming Xu, Shengjie Hong, Jicai Wang, Hang Zhai, Qiang Tao, Ruixi Li, Guangquan Zhang, Xianjie Shi   +9 more
doaj   +1 more source

Evaluation of drug interactions in outpatients taking antipsychotic medications

Frontiers in Pharmacology
IntroductionDrug-drug interactions (DDIs) of antipsychotic medications are clinically significant as they can result in toxicity or treatment failure.
Bshra A. Alsfouk, Qamar M. Aljanadi, Mona M. Almutairi   +2 more
doaj   +1 more source