Results 41 to 50 of about 201,194 (169)
Frontiers in PharmacologyIntroductionThis systematic review evaluates the efficacy of the Chinese herbal formula modified Danggui Sini Decoction as an adjunctive treatment for angina pectoris in patients with coronary heart disease.MethodsWe conducted a comprehensive search for ...
He Wang +4 more
doaj +1 more source
Journal of Biological Chemistry, 2019 Protein substrates are targeted to the 26S proteasome through several ubiquitin receptors. One of these receptors, RPN13, is recruited to the proteasome by binding of its N-terminal pleckstrin-like receptor of ubiquitin (PRU) domain to C-terminal ...
C. W. Hemmis, S. Heard, C. Hill
semanticscholar +1 more source
Exploring orphan GPCRs in neurodegenerative diseases
Frontiers in PharmacologyNeurodegenerative disorders represent a significant and growing health burden worldwide. Unfortunately, limited therapeutic options are currently available despite ongoing efforts.
Devrim Öz-Arslan +5 more
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Design and Performance of a Sideband Separating SIS Mixer for 800–950 GHz
IEEE Transactions on Terahertz Science and Technology, 2019 We present the design and results of characterization of a new sideband separating (2SB) mixer for 800–950 GHz, based on superconductor–insulator–superconductor (SIS) junctions.
A. Khudchenko +13 more
semanticscholar +1 more source
Long-term effects of neonatal pain and sucrose treatment
Current Research in Pharmacology and Drug DiscoveryPurpose: In neonatal intensive care units, applying sucrose solution for analgesia is now a routine treatment for mild procedural pain. Studies of animal and human infants provide clear evidence of benefits in the short term, but few studies have ...
Khawla Nuseir +6 more
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Pharmaceutical company payments to Japanese breast cancer practice guideline authors
Clinical and Translational DiscoveryBackground The creation of breast cancer practice guidelines requires proper management of financial relationships with drug companies, as they can introduce conflicts of interest (COIs) among guideline authors.
Anju Murayama +4 more
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Energy substrate supplementation increases ATP levels and is protective to PD neurons
Current Research in Pharmacology and Drug DiscoveryAlteration of mitochondrial metabolism by various mutations or toxins leads to various neurological conditions. Age-related changes in energy metabolism could also play the role of a trigger for neurodegenerative disorders.
Andrey Y. Vinokurov +4 more
doaj +1 more source
Intervertebral disc degeneration and regenerative medicine
Clinical and Translational DiscoveryIntervertebral disc (IVD) degeneration is a common phenomenon that affects patients with increasing prevalence with increasing age. Both conservative treatments, such as the use of pain medication or physical therapy, and surgical treatments, such as ...
Mariam Farag +4 more
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Development of Recombinant Antibody by Yeast Surface Display Technology
Current Research in Pharmacology and Drug DiscoveryRecombinant antibodies have emerged as powerful tools in various fields, including therapeutics, diagnostics, and research applications. The selection of high-affinity antibodies with desired specificity is a crucial step in the development of ...
Mujahed I. Mustafa +2 more
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Frontiers in PharmacologyBackgroundPersistent post-infectious symptoms, predominantly fatigue, characterize Long COVID. This study investigated the efficacy of Myelophil (MYP), which contains metabolites extracted from Astragalus membranaceus and Salvia miltiorrhiza using 30 ...
Jin-Yong Joung +10 more
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