Results 21 to 30 of about 162,144 (130)

Sustained efficacy of chimeric antigen receptor T-cell therapy in central nervous system lymphoma: a systematic review and meta-analysis of individual data

Frontiers in Pharmacology
Background: Central nervous system lymphoma (CNSL) is considered an aggressive lymphoma with a poor prognosis. Studies investigating CNSL have shown that chimeric antigen receptor (CAR) T-cell therapy has demonstrated an effective response in limited ...
Jing Zhou, Zhenhao Wang, Hanyu Wang, Yang Cao, Gaoxiang Wang   +4 more
doaj   +1 more source

ISEV2021 Abstract Book

, 2021
Journal of Extracellular Vesicles, Volume 10, Issue S1, May 2021.
wiley   +1 more source

Therapeutic evolution in HR+/HER2- breast cancer: from targeted therapy to endocrine therapy

Frontiers in Pharmacology
Breast cancer, a complex and varied disease, has four distinct subtypes based on estrogen receptor and human epidermal growth factor receptor 2 (HER2) levels, among which a significant subtype known as HR+/HER2-breast cancer that has spurred numerous ...
Lu-Qi Cao, Lu-Qi Cao, Haidong Sun, Yuhao Xie, Harsh Patel, Letao Bo, Hanli Lin, Zhe-Sheng Chen, Zhe-Sheng Chen   +8 more
doaj   +1 more source

Hypoxia inducible factor-1ɑ as a potential therapeutic target for osteosarcoma metastasis

Frontiers in Pharmacology
Osteosarcoma (OS) is a malignant tumor originating from mesenchymal tissue. Pulmonary metastasis is usually present upon initial diagnosis, and metastasis is the primary factor affecting the poor prognosis of patients with OS. Current research shows that
Jianghu Zhou, Fengjun Lan, Miao Liu, Fengyan Wang, Xu Ning, Hua Yang, Hong Sun   +6 more
doaj   +1 more source

Sociodemographic and clinical predictors of adherence to antidepressants in depressive disorders: a systematic review with a meta-analysis

Frontiers in Pharmacology
Introduction: Current evidence reveals concerning rates of non-adherence to antidepressant treatment, possibly influenced by various relevant determinants such as sociodemographic factors or those related to the health system and their professionals. The
Tasmania Del Pino-Sedeño, Tasmania Del Pino-Sedeño, Tasmania Del Pino-Sedeño, Tasmania Del Pino-Sedeño, Tasmania Del Pino-Sedeño, Diego Infante-Ventura, Diego Infante-Ventura, Diego Infante-Ventura, Diego Hernández-González, Yadira González-Hernández, Yadira González-Hernández, Beatriz González de León, Amado Rivero-Santana, Amado Rivero-Santana, Amado Rivero-Santana, Isabel Hurtado, Isabel Hurtado, Francisco Javier Acosta Artiles, Francisco Javier Acosta Artiles   +18 more
doaj   +1 more source

For special purposes only: Ceramic casting moulds from the late Bronze and Early Iron Age metallurgical workshop in Grzybiany (SW Poland)

Archaeometry, Volume 67, Issue 2, Page 482-501, April 2025.
Abstract Ceramic moulds are regarded as highly specialised, refractory tools used in metallurgy, yet their production process still needs clarification. Our research aimed to characterise the stages of operational chains applied in mould manufacture. The evidence comes from the Late Bronze and Early Iron Age lake settlement in Grzybiany in SW Poland ...
Wojciech Bartz, Kamil Nowak, Tomasz Stolarczyk, Justyna Baron   +3 more
wiley   +1 more source

Polyphenols and extracts from Zingiber roseum (Roxb.) Roscoe leaf mitigate pain, inflammation and pyrexia by inhibiting cyclooxygenase-2: an in vivo and in silico studies

Frontiers in Pharmacology
Zingiber roseum (Roxb.) Roscoe, a perennial herb from the Zingiberaceae family, has a long history of traditional use in the treatment of several ailments including pain, inflammation, fever, cough, arthritis, skin diseases, and liver infections.
Shakhawat Ahmed, Khondoker Shahin Ahmed, Md. Naiemur Rahman, Hemayet Hossain, Aixia Han, Peiwu Geng, A. F. M. Shahid Ud Daula, Abdullah Al Mamun   +7 more
doaj   +1 more source

Development of calcium sulfoaluminate cements from rich‐alumina bauxite and marble wastes: Physicochemical and microstructural characterization

International Journal of Ceramic Engineering &Science, Volume 6, Issue 3, May 2024.
Abstract This work discusses the effect of rich alumina bauxite on the mineralogical composition of calcium sulfoaluminate (CSA) clinker cement on their performances. After preparation of different local raw materials (rich alumina bauxite and marble), they were mixed with 15 wt% of commercial gypsum and pressed at 2 MPa.
Gaëlle Annick Nyonda Yanze, Achile Nana, Patrick Ninla Lemougna, Rodrigue Cyriaque Kaze, Sylvain Tome, Hubert Rahier, Elie Kamseu, Florence Uphie Chinje   +7 more
wiley   +1 more source

Potential pharmacological mechanisms of tanshinone IIA in the treatment of human neuroblastoma based on network pharmacological and molecular docking Technology

Frontiers in Pharmacology
Tanshinone IIA (Tan-IIA) is the main bioactive component of Chinese herbal medicine salvia miltiorrhiza (Danshen). Sodium sulfonate of Tan-IIA is widely used in the treatment of cardiovascular and cerebrovascular diseases.
Ning Tang, Yan Wang, Jiarui Miao, Yang Zhao, Yue Cao, Wentao Sun, Jingke Zhang, Hua Sui, Bing Li   +8 more
doaj   +1 more source

Automated Input Variable Selection for Analog Methods Using Genetic Algorithms

Water Resources Research, Volume 60, Issue 4, April 2024.
Abstract Analog methods (AMs) have long been used for precipitation prediction and climate studies. However, they rely on manual selections of parameters, such as predictor variables and analogy criteria. Previous work showed the potential of genetic algorithms (GAs) to optimize most of the AM parameters.
P. Horton, O. Martius, S. L. Grimm
wiley   +1 more source