Overlapping transcription and bacterial RNA removal [PDF]
The precise understanding of the biology of a living cell requires the identification and quantification of the molecular components necessary to sustain life. One such element is RNA. Two independent high-throughput strategies are available to identify the entire collection of RNA molecules produced by a cell population, which is currently known as ...
Lasa Uzcudun, Íñigo+1 more
openaire +5 more sources
Nasal Bacterial Microbiome: Probing a Healthy Porcine Family [PDF]
Upper respiratory tract (URT) infection caused the leading and devastating diseases in pigs. It was believed that the normal microbiome of URT plays a vital role in health and disease development.
Huanchun Chen, Min Yue, Weicheng Bei
core +2 more sources
Bacterial ribonucleases and their roles in RNA metabolism
Ribonucleases (RNases) are mediators in most reactions of RNA metabolism. In recent years, there has been a surge of new information about RNases and the roles they play in cell physiology.
D. Bechhofer, M. Deutscher
semanticscholar +1 more source
Prediction of Novel Bacterial Small RNAs From RIL-Seq RNA–RNA Interaction Data
The genomic revolution and subsequent advances in large-scale genomic and transcriptomic technologies highlighted hidden genomic treasures. Among them stand out non-coding small RNAs (sRNAs), shown to play important roles in post-transcriptional ...
Amir Bar+3 more
doaj +1 more source
Idiosyncratic evolution of conserved eukaryote proteins that are similar in sequence to archaeal or bacterial proteins [PDF]
Sequence comparisons have been made between the proteins of 571 prokaryote species including 46 archaea and 525 bacteria and the set of human proteins.
Roy J. Britten
core +2 more sources
Extracellular vesicles deliver Mycobacterium RNA to promote host immunity and bacterial killing
Extracellular vesicles (EVs) have been shown to carry microbial components and function in the host defense against infections. In this study, we demonstrate that Mycobacterium tuberculosis (M.tb) RNA is delivered into macrophage‐derived EVs through an M.
Yong Cheng, Jeff S. Schorey
semanticscholar +1 more source
Bacterial small RNAs in the Genus Rickettsia [PDF]
Rickettsia species are obligate intracellular Gram-negative pathogenic bacteria and the etiologic agents of diseases such as Rocky Mountain spotted fever (RMSF), Mediterranean spotted fever, epidemic typhus, and murine typhus. Genome sequencing revealed that R. prowazekii has ~25 % non-coding DNA, the majority of which is thought to be either "junk DNA"
Casey L. C. Schroeder+8 more
openaire +3 more sources
Background The amplification of bacterial RNA is required if complex host-pathogen interactions are to be studied where the recovery of bacterial RNA is limited.
Butcher Philip D+3 more
doaj +1 more source
Salmonella produce microRNA-like RNA fragment Sal-1 in the infected cells to facilitate intracellular survival. [PDF]
Salmonella have developed a sophisticated machinery to evade immune clearance and promote survival in the infected cells. Previous studies were mostly focused on either bacteria itself or host cells, the interaction mechanism of host-pathogen awaits ...
Chen, Xi+11 more
core +2 more sources
Large-scale and significant expression from pseudogenes in Sodalis glossinidius – a facultative bacterial endosymbiont [PDF]
The majority of bacterial genomes have high coding efficiencies, but there are some genomes of intracellular bacteria that have low gene density. The genome of the endosymbiont Sodalis glossinidius contains almost 50 % pseudogenes containing mutations ...
Beynon, R+9 more
core +2 more sources