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Quantitative RNA pseudouridine landscape reveals dynamic modification patterns and evolutionary conservation across bacterial species [PDF]
eLifePseudouridine (Ψ) modifications are the most abundant RNA modifications; however, their distribution and functional significance in bacteria remain largely unexplored compared to eukaryotic systems.
Letong Xu +9 more
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Canonical transcription termination mechanisms explain a minority of operons in cyanobacteria [PDF]
mSystemsCyanobacteria are abundant phototrophs and hold potential as a carbon-negative platform for bioengineering applications. However, these efforts have been hampered by limited mechanistic understanding of their gene expression, including transcription ...
Jennifer A. Cascino +6 more
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Enriching Bacteria-Specific RNA From Host Samples Before NGS With Transcript-Capture [PDF]
Bio-ProtocolPathogen gene expression from host samples is often challenging to study due to low signal and high host RNA background. PCR probes have been recently used to hybridize and extract bacterial sequences from next-generation sequencing (NGS) libraries ...
Eleanor Lamont +4 more
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Frontiers in Veterinary Science, 2023 Bacteria of the genus Salmonella pose a major risk to livestock, the food economy, and public health. Salmonella infections are one of the leading causes of food poisoning.
Christine Thomas +4 more
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FEMS Microbiology Reviews, 2015 Transfer RNA is an essential adapter molecule that is found across all three domains of life. The primary role of transfer RNA resides in its critical involvement in the accurate translation of messenger RNA codons during protein synthesis and, therefore, ultimately in the determination of cellular gene expression.
Shepherd, Jennifer, Ibba, Michael
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BMC Genomics, 2023 Background Chlamydia (C.) psittaci, the causative agent of avian chlamydiosis and human psittacosis, is a genetically heterogeneous species. Its broad host range includes parrots and many other birds, but occasionally also humans (via zoonotic ...
Konrad Sachse +7 more
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Processing of bacterial RNA [PDF]
FEBS Letters, 1981 Processing of RNA is a feature of RNA metabolism which contributes to the determination of the fmal population of active RNA molecules in the cell. Pro- cessing is the sum of events which converts a primary RNA transcript into a functional molecule. RNA processing in bacteria consists mainly of two parts, modification of nucleotides and cutting and ...
Apirion, David, Gegenheimer, Peter
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Bacterial Small RNA Regulators [PDF]
Critical Reviews in Biochemistry and Molecular Biology, 2005 Small regulatory RNAs can modify the activity of proteins and the stability and translation of mRNAs. They have now been found in a wide range of organisms, and can play previously unsuspected critical regulatory roles. The bacterial small RNAs include two major classes.
Majdalani, Nadim +2 more
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RNA Thermometers in Bacterial Pathogens [PDF]
Microbiology Spectrum, 2018 ABSTRACT Temperature variation is one of the multiple parameters a microbial pathogen encounters when it invades a warm-blooded host. To survive and thrive at host body temperature, human pathogens have developed various strategies to sense and respond to their ambient temperature.
Loh, Edmund +4 more
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Pathogens, 2020 To identify genome-based features characteristic of the avian and human pathogen Chlamydia (C.) psittaci and related chlamydiae, we analyzed whole-genome sequences of 33 strains belonging to 12 species. Using a novel genome analysis tool termed Roary ILP
Martin Hölzer +9 more
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