Results 101 to 110 of about 34,514 (185)

Guide RNA structure design enables combinatorial CRISPRa programs for biosynthetic profiling

Nature Communications
Engineering metabolism to efficiently produce chemicals from multi-step pathways requires optimizing multi-gene expression programs to achieve enzyme balance.
Jason Fontana, David Sparkman-Yager, Ian Faulkner, Ryan Cardiff, Cholpisit Kiattisewee, Aria Walls, Tommy G. Primo, Patrick C. Kinnunen, Hector Garcia Martin, Jesse G. Zalatan, James M. Carothers   +10 more
doaj   +1 more source

Applications and Challenges of CRISPR-Cas Technology for the Detection of Antimicrobial Resistance Genes. [PDF]

Infect Drug Resist
Tang W, Yang N, Shi M.
europepmc   +1 more source

Prokaryotic defense systems: Diversity and evolutionary adaptation. [PDF]

mLife
Yang C, Gong L, Guo J, Xiang H.
europepmc   +1 more source

Chronic In Vivo CRISPR-Cas Genome Editing: Challenges, Long-Term Safety, and Outlook. [PDF]

Cells
Bao C, Channell CI, Tseng YH, Bailey J, Sbaiti N, Demirkol A, Tsang SH.   +6 more
europepmc   +1 more source

Functional characterization of a type I-F1 CRISPR-cas system from the clinical isolate Shewanella xiamenensis Sh95 reveals constitutive activity and plasmid-curing capability. [PDF]

Sci Rep
Molina MC, Quiroga C.
europepmc   +1 more source

Advances in Double-Stranded DNA Targeting Technologies. [PDF]

Exploration (Beijing)
Shen Z, Liu Y, Hao Y, Bo Y, Dai X, Wang S, Xia T, Su X, Liu H.   +8 more
europepmc   +1 more source

Disrupting Viral Persistence: CRISPR/Cas9-Based Strategies for Hepatitis B and C Treatment, and Challenges. [PDF]

J Cell Mol Med
Li MF, Zubair A, Wdidi S, He S.
europepmc   +1 more source

CRISPR-Cas technologies in neurodegenerative disorders: mechanistic insights, therapeutic potential, and translational challenges. [PDF]

Front Neurol
Yashooa RK, Nabi AQ, Smail SW, Azeez SS, Nooh WA, Mustafa SA, Al-Farha AA, Capitanio N, Shekha MS.   +8 more
europepmc   +1 more source

Research progress and applications of gene activation editing technology in crops. [PDF]

Front Plant Sci
Lv J, He X, Wu Q, Sun Y, Pu W, Dai C.
europepmc   +1 more source

What If Trojan Horse Nanoparticles Could Change the Game for HPV Gene-Targeted Therapies? [PDF]

J Med Virol
Chokwassanasakulkit T, Ranasinghe V, Woods E, Nguyen LQ, McMillan NAJ.   +4 more
europepmc   +1 more source