Results 161 to 170 of about 34,514 (185)

The new CRISPR–Cas system: RNA-guided genome engineering to efficiently produce any desired genetic alteration in animals

Transgenic Research, 2014
The CRISPR-Cas system is the newest targeted nuclease for genome engineering. In less than 1 year, the ease, robustness and efficiency of this method have facilitated an immense range of genetic modifications in most model organisms. Full and conditional gene knock-outs, knock-ins, large chromosomal deletions and subtle mutations can be obtained using ...
Davide, Seruggia, Lluis, Montoliu
openaire   +2 more sources

CRISPR/Cas System Photocontrolled at the Guide RNA Level

Biophysics
Improving the efficiency and precision of gene editing systems is of utmost importance for modern molecular biology and genetic engineering. Of particular interest is the design of controlled CRISPR/Cas9 systems, the activity of which could be regulated using different physico-chemical stimuli such as light irradiation, pH change, temperature, change ...
L. V Sakovina, E. S Gorlenko, D. S Novopashina   +2 more
openaire   +1 more source

Alternative functions of CRISPR–Cas systems in the evolutionary arms race

Nature Reviews Microbiology, 2022
Prarthana Mohanraju, Chinmoy Saha, Peter van Baarlen   +2 more
exaly  

Structural biology of CRISPR–Cas immunity and genome editing enzymes

Nature Reviews Microbiology, 2022
Joy Y Wang, Patrick Pausch, Jennifer A Doudna   +2 more
exaly  

RNA-targeting CRISPR–Cas systems

Nature Reviews Microbiology, 2022
Alicia Rodríguez-Molina, Stan J J Brouns   +1 more
exaly  

Faculty Opinions recommendation of Transposon-encoded CRISPR-Cas systems direct RNA-guided DNA integration.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2019
Luciano Marraffini, Alexander Meeske
openaire   +1 more source

Faculty Opinions recommendation of Transposon-encoded CRISPR-Cas systems direct RNA-guided DNA integration.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2020
openaire   +1 more source

Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants

Nature Reviews Microbiology, 2019
Kira S Makarova, Yuri I Wolf, Jaime Iranzo   +2 more
exaly  

Diversity and evolution of class 2 CRISPR–Cas systems

Nature Reviews Microbiology, 2017
Sergey Shmakov, David A Scott, David B T Cox   +2 more
exaly  

CRISPR–Cas in mobile genetic elements: counter-defence and beyond

Nature Reviews Microbiology, 2019
Guilhem Faure, Sergey A Shmakov, Winston X Yan   +2 more
exaly