Results 1 to 10 of about 398,772 (311)
Messenger RNA Fluctuations and Regulatory RNAs Shape the Dynamics of Negative Feedback Loop [PDF]
Phys. Rev. E 81, 031924 (2010), 2010 Single cell experiments of simple regulatory networks can markedly differ from cell population experiments. Such differences arise from stochastic events in individual cells that are averaged out in cell populations. For instance, while individual cells may show sustained oscillations in the concentrations of some proteins, such oscillations may appear
Furman, Itay +4 more
arxiv +3 more sources
Matrices Activated with Messenger RNA
Journal of Functional Biomaterials, 2023 Over two decades of preclinical and clinical experience have confirmed that gene therapy-activated matrices are potent tools for sustained gene modulation at the implantation area.
Raquel Martinez-Campelo +1 more
doaj +3 more sources
Who discovered messenger RNA? [PDF]
Current Biology, 2015 The announcement of the discovery of messenger RNA (mRNA) and the cracking of the genetic code took place within weeks of each other in a climax of scientific excitement during the summer of 1961. Although mRNA is of decisive importance to our understanding of gene function, no Nobel Prize was awarded for its discovery.
Cobb, Matthew
openaire +6 more sources
Comment on "Length-dependent translation of messenger RNA by ribosomes" [PDF]
Physical Review E, 85(2012), 023901, 2011 In the recent paper of Valleriani {\it et al} [Phys. Rev. E {\bf 83}, 042903 (2011)], a simple model for describing the translation of messenger RNA (mRNA) by ribosomes is presented, and an expression of the translational ratio $r$, defined as the ratio of translation rate $\omega_{\rm tl}$ of protein from mRNA to degradation rate $\omega_p$ of protein,
J. Howard, Yunxin Zhang
arxiv +3 more sources
Differentially Expressed mRNA in Streptozotocin-Induced Diabetic Bladder Using RNA Sequencing Analysis [PDF]
International Neurourology Journal, 2023 Purpose To detect elements governing the pathogenesis of diabetic cystopathy (DC), mRNA sequencing was carried out for bladder tissues from normal rats and those with induced diabetes mellitus (DM).
Jae Heon Kim +3 more
doaj +1 more source
Gene expression of chemokines CX3CL1 and CXCL16 and their receptors, CX3CR1 and CXCR6, in peripheral blood mononuclear cells of patients with relapsing-remitting multiple sclerosis - a pilot study [PDF]
Vojnosanitetski Pregled, 2020 Background/Aim. In vitro and in vivo studies show that CX3CL1 and CXCL16 chemokines and their specific receptors, CX3CR1 and CXCR6, respectively, mediate mechanism of neuroinflammation during the pathogenesis of multiple sclerosis (MS).
Stojković Ljiljana +5 more
doaj +1 more source
Technology in Cancer Research & Treatment, 2021 Objectives: Epidermal growth factor receptor-tyrosine kinase inhibitors are widely used for lung epidermal growth factor receptor-positive lung adenocarcinomas, but acquired resistance is inevitable.
Chenyue Dai MM +7 more
doaj +1 more source
HIV mRNA Vaccines—Progress and Future Paths
Vaccines, 2021 The SARS-CoV-2 pandemic introduced the world to a new type of vaccine based on mRNA encapsulated in lipid nanoparticles (LNPs). Instead of delivering antigenic proteins directly, an mRNA-based vaccine relies on the host’s cells to manufacture protein ...
Zekun Mu +2 more
doaj +1 more source
Real-Time Messenger RNA Dynamics in Bacillus subtilis
Frontiers in Microbiology, 2021 Messenger RNA molecules have been localized to different positions in cells and have been followed by time-lapse microscopy. We have used MS2-mVenus–labeled mRNA and single-particle tracking to obtain information on the dynamics of single-mRNA molecules ...
Laura Sattler, Peter L. Graumann
doaj +1 more source
PLoS Pathogens, 2021 Respiratory syncytial virus (RSV) is a major cause of respiratory disease in infants and the elderly. RSV is a non-segmented negative strand RNA virus.
Molly R Braun +6 more
doaj +1 more source