Results 1 to 10 of about 1,347,350 (288)
Alterations in micro RNA-messenger RNA (miRNA-mRNA) Coupled Signaling Networks in Sporadic Alzheimer's Disease (AD) Hippocampal CA1. [PDF]
J Alzheimers Dis Parkinsonism, 2017 RNA sequencing, DNA microfluidic array, LED-Northern, Western immunoassay and bioinformatics analysis have uncovered a small family of up-regulated human brain enriched microRNAs (miRNAs) and down-regulated messenger RNAs (mRNAs) in short post-mortem ...
Jaber V, Zhao Y, Lukiw WJ.
europepmc +2 more sources
Matrices Activated with Messenger RNA
Journal of Functional Biomaterials, 2023 Over two decades of preclinical and clinical experience have confirmed that gene therapy-activated matrices are potent tools for sustained gene modulation at the implantation area.
Raquel Martinez-Campelo +1 more
doaj +3 more sources
Differentially Expressed mRNA in Streptozotocin-Induced Diabetic Bladder Using RNA Sequencing Analysis [PDF]
International Neurourology Journal, 2023 Purpose To detect elements governing the pathogenesis of diabetic cystopathy (DC), mRNA sequencing was carried out for bladder tissues from normal rats and those with induced diabetes mellitus (DM).
Jae Heon Kim +3 more
doaj +1 more source
Gene expression of chemokines CX3CL1 and CXCL16 and their receptors, CX3CR1 and CXCR6, in peripheral blood mononuclear cells of patients with relapsing-remitting multiple sclerosis - a pilot study [PDF]
Vojnosanitetski Pregled, 2020 Background/Aim. In vitro and in vivo studies show that CX3CL1 and CXCL16 chemokines and their specific receptors, CX3CR1 and CXCR6, respectively, mediate mechanism of neuroinflammation during the pathogenesis of multiple sclerosis (MS).
Stojković Ljiljana +5 more
doaj +1 more source
Journal of the American Medical Association (JAMA), 2021 Immunogenicity of a Single Dose of SARS-CoV-2 Messenger RNA Vaccine in Solid Organ Transplant Recipients Immunocompromised individuals have been excluded from studies of SARS-CoV-2 messenger RNA (mRNA) vaccines.
B. Boyarsky +6 more
semanticscholar +1 more source
JAMA Oncology, 2021 Key Points Question Do patients with cancer develop adequate antibody responses to messenger RNA SARS-CoV-2 vaccines? Findings In this cohort study that included 102 patients with cancer who were receiving active treatment and 78 healthy controls, 92 ...
Amir Massarweh +14 more
semanticscholar +1 more source
PLoS Pathogens, 2021 Respiratory syncytial virus (RSV) is a major cause of respiratory disease in infants and the elderly. RSV is a non-segmented negative strand RNA virus.
Molly R Braun +6 more
doaj +1 more source
Technology in Cancer Research & Treatment, 2021 Objectives: Epidermal growth factor receptor-tyrosine kinase inhibitors are widely used for lung epidermal growth factor receptor-positive lung adenocarcinomas, but acquired resistance is inevitable.
Chenyue Dai MM +7 more
doaj +1 more source
HIV mRNA Vaccines—Progress and Future Paths
Vaccines, 2021 The SARS-CoV-2 pandemic introduced the world to a new type of vaccine based on mRNA encapsulated in lipid nanoparticles (LNPs). Instead of delivering antigenic proteins directly, an mRNA-based vaccine relies on the host’s cells to manufacture protein ...
Zekun Mu +2 more
doaj +1 more source
Real-Time Messenger RNA Dynamics in Bacillus subtilis
Frontiers in Microbiology, 2021 Messenger RNA molecules have been localized to different positions in cells and have been followed by time-lapse microscopy. We have used MS2-mVenus–labeled mRNA and single-particle tracking to obtain information on the dynamics of single-mRNA molecules ...
Laura Sattler, Peter L. Graumann
doaj +1 more source