Results 1 to 10 of about 297,630 (163)

The Aberrant Expression of MicroRNA-125a-5p/IGF2BP3 Axis in Advanced Gastric Cancer and Its Clinical Relevance

open access: yesTechnology in Cancer Research & Treatment, 2020
RNA-binding proteins have been associated with cancer development. The overexpression of a well-known RNA-binding protein, insulin-like growth factor 2 messenger RNA–binding protein 3, has been identified as an indicator of poor prognosis in patients ...
Jing Zhang MS   +4 more
doaj   +1 more source

From Viral Vaccines to Messenger RNA Vaccines

open access: yesPakistan Journal of Medicine and Dentistry, 2020
Today, the swiftness of epidemics of infectious disease is alarming. To date vaccines have been an enormous success for not only preventing but completely eradicating a number of malicious infectious disease like small pox, rubella, mumps, measles and ...
Saeeda Baig, Zoha Asghar
doaj   +1 more source

Vaccines against Coronavirus Type 19: An Overview [PDF]

open access: yesAl-Anbar Medical Journal, 2023
Vaccines are biological agents that provide immunity against certain diseases [1]. Vaccination is an effective technique for prevention of infection and control outbreak of a wide range of infectious diseases (https://apps.who.int/iris/handle/10665 ...
Makwan Abdulkareem
doaj   +1 more source

Circular RNA hsa_circ_0000376 Participates in Tumorigenesis of Breast Cancer by Targeting miR-1285-3p

open access: yesTechnology in Cancer Research & Treatment, 2020
This study was designed to identify novel circular RNAs and the related regulatory axis to provide research targets for the diagnosis and treatment of breast cancer.
Ziqi Peng BM, Boyang Xu BM, Feng Jin MD
doaj   +1 more source

Cotranslational microRNA mediated messenger RNA destabilization

open access: yeseLife, 2016
MicroRNAs are small (22 nucleotide) regulatory molecules that play important roles in a wide variety of biological processes. These RNAs, which bind to targeted mRNAs via limited base pairing interactions, act to reduce protein production from those ...
Trinh To Tat   +4 more
doaj   +1 more source

Lymph node CXCL17 messenger RNA: A new prognostic biomarker for colon cancer

open access: yesTumor Biology, 2018
Lymph node metastasis is the most important prognostic characteristic of colorectal cancer. Carcinoembryonic antigen messenger RNA was shown to detect tumor cells that have disseminated to lymph nodes of colorectal cancer patients and to be at least as ...
Yomna Rashad   +7 more
doaj   +1 more source

Structural signatures of thermal adaptation of bacterial ribosomal RNA, transfer RNA, and messenger RNA. [PDF]

open access: yesPLoS ONE, 2017
Temperature adaptation of bacterial RNAs is a subject of both fundamental and practical interest because it will allow a better understanding of molecular mechanism of RNA folding with potential industrial application of functional thermophilic or ...
Clara Jegousse   +4 more
doaj   +1 more source

Improper preanalytical processes on peripheral blood compromise RNA quality and skew the transcriptional readouts of mRNA and LncRNA

open access: yesFrontiers in Genetics, 2023
Genetic and epigenetic reprogramming caused by disease states in other tissues is always systemically reflected in peripheral blood leukocytes (PBLs).
Yinli He   +10 more
doaj   +1 more source

The emerging role of RNA modifications in the regulation of mRNA stability

open access: yesExperimental and Molecular Medicine, 2020
Gene activity: the significance of RNA modification Messenger RNA molecules play their key role in directing the manufacture of proteins via translating the genetic information in DNA.
Sung Ho Boo, Yoon Ki Kim
doaj   +1 more source

Modelling ribosome kinetics and translational control on dynamic mRNA.

open access: yesPLoS Computational Biology, 2023
The control of protein synthesis and the overall levels of various proteins in the cell is critical for achieving homoeostasis. Regulation of protein levels can occur at the transcriptional level, where the total number of messenger RNAs in the overall ...
Eric C Dykeman
doaj   +1 more source

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