This study was designed to identify novel circular RNAs and the related regulatory axis to provide research targets for the diagnosis and treatment of breast cancer.
Ziqi Peng BM, Boyang Xu BM, Feng Jin MD
doaj +1 more source
Vaccines against Coronavirus Type 19: An Overview [PDF]
Vaccines are biological agents that provide immunity against certain diseases [1]. Vaccination is an effective technique for prevention of infection and control outbreak of a wide range of infectious diseases (https://apps.who.int/iris/handle/10665 ...
Makwan Abdulkareem
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Hepatitis C virus 3'UTR regulates viral translation through direct interactions with the host translation machinery. [PDF]
The 3' untranslated region (3'UTR) of hepatitis C virus (HCV) messenger RNA stimulates viral translation by an undetermined mechanism. We identified a high affinity interaction, conserved among different HCV genotypes, between the HCV 3'UTR and the host ...
Bai, Yun+2 more
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The roles of the subunits in the function of the calcium channel [PDF]
Dihydropyridine-sensitive voltage-dependent L-type calcium channels are critical to excitation-secretion and excitation-contraction coupling. The channel molecule is a complex of the main, pore-forming subunit alpha 1 and four additional subunits: alpha ...
Biel, Martin+5 more
core +1 more source
Ultrastructure of the ribonucleoprotein and messenger-like ribonucleic acid of the polyribosomes isolated from Rous sarcoma virus-induced mouse ascites sarcoma cells [PDF]
Electron microscopic observation was made on the length distibution of messenger RNA molecules in polyribosome pre· paration isolated from mouse ascites sarcoma cells, which was de· stroyed by ethylenediamine tetraacetate treatment in hypotonic solu ...
Oda, Takuzo, Yamamoto, Goki
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Cotranslational microRNA mediated messenger RNA destabilization
MicroRNAs are small (22 nucleotide) regulatory molecules that play important roles in a wide variety of biological processes. These RNAs, which bind to targeted mRNAs via limited base pairing interactions, act to reduce protein production from those ...
Trinh To Tat+4 more
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m6A-dependent regulation of messenger RNA stability
N6-methyladenosine (m6A) is the most prevalent internal (non-cap) modification present in the messenger RNA of all higher eukaryotes. Although essential to cell viability and development, the exact role of m6A modification remains to be determined.
Xiao Wang+12 more
semanticscholar +1 more source
Lymph node CXCL17 messenger RNA: A new prognostic biomarker for colon cancer
Lymph node metastasis is the most important prognostic characteristic of colorectal cancer. Carcinoembryonic antigen messenger RNA was shown to detect tumor cells that have disseminated to lymph nodes of colorectal cancer patients and to be at least as ...
Yomna Rashad+7 more
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HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs [PDF]
HuR/ELAVL1 is an RNA-binding protein involved in differentiation and stress response that acts primarily by stabilizing messenger RNA (mRNA) targets. HuR comprises three RNA recognition motifs (RRMs) where the structure and RNA binding of RRM3 and of ...
Asami S+4 more
core +1 more source
A small RNA response at DNA ends in Drosophila [PDF]
Small RNAs have been implicated in numerous cellular processes, including effects on chromatin structure and the repression of transposons. We describe the generation of a small RNA response at DNA ends in Drosophila that is analogous to the recently ...
Böttcher, Romy+2 more
core +1 more source