Results 201 to 210 of about 126,755 (277)

Transcriptomic profiling of ceftriaxone-tolerant phenotypes of <i>Neisseria gonorrhoeae</i> reveals downregulation of ribosomal genes - a pilot study. [PDF]

Microbiol Spectr
Manoharan-Basil SS, Balduck M, Gestels Z, Abdellati S, De Block T, Kenyon C.   +5 more
europepmc   +1 more source

Autoantibody Response Toward Chromatin in Patients With Juvenile Idiopathic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Patients with juvenile idiopathic arthritis (JIA) frequently exhibit antinuclear antibodies (ANAs), but the specific antigen target recognized by them and the presence of additional autoantibody specificities in patients with JIA remains elusive.
Viola Pitkänen, Terhi Remes‐Pakarinen, Paula Vähäsalo, Milja Möttönen, Minna‐Maija Grönlund, Miika Arvonen, Mikael Knip, Riitta Veijola, Jorma Toppari, Jorma Ilonen, Johanna Lempainen, Anna‐Mari Schroderus, Liisa Kröger, Tuure Kinnunen   +13 more
wiley   +1 more source

Transcriptomic profiling of milk fat globules in cows with different β-casein genotypes. [PDF]

Sci Rep
Jiménez-Montenegro L, Alfonso L, Soret B, Mendizabal JA, Urrutia O.   +4 more
europepmc   +1 more source

Telomere Length of Peripheral Blood Leukocytes Predicts Disease Severity and Worse Survival in Systemic Sclerosis

Arthritis &Rheumatology, Accepted Article.
Objective Peripheral blood leukocyte telomere length (PBL‐TL) shortening is associated with systemic sclerosis related interstitial lung disease (SSc‐ILD). However, its association with other organ involvement, disease severity, and survival remains unclear.
Monica M. Yang, Shuo Liu, Michael Wax II, Seoyeon Lee, Sarah French, Paul J. Wolters, Francesco Boin   +6 more
wiley   +1 more source

Blood RNA biomarkers and a point-of-care elastase assay for detecting host immune activation in suspected sepsis: Trajectory matters. [PDF]

PLoS One
Lafleur JE, Shaykhinurov E, Perkins J, Wargowsky R, Jaatinen K, Pasquale M, Holloway G, Yamane D, Patel A, King D, Meltzer A, Heidish R, Shahamatdar S, Loganathan A, Loganathan T, Bolden T, Hayden MZ, Maddali A, Goldman J, Falk Z, Jepson T, League A, McCaffrey TA.   +22 more
europepmc   +1 more source

RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic target

Cancer Communications, EarlyView.
Abstract Background The role of N1‐methyladenosine (m1A) in cancer is poorly understood. Here we explored the function of RNA methyltransferase TRNA methyltransferase 61A (TRMT61A) in colorectal cancer (CRC) and its potential as a therapeutic target. Methods RNA m1A levels were assessed through liquid chromatography‐mass spectrometry.
Xiaoting Zhang, Na Qin, Fenfen Ji, Hao Su, Haiyun Shang, Hongyan Chen, Dan Huang, Qing Li, Jing Ren, Weixin Liu, Yifei Wang, Wei Kang, Jiabin Wu, Chi‐Chun Wong, Zongwei Cai, Matthew Tak Vai Chan, William Ka Kei Wu, Jun Yu, Huarong Chen   +18 more
wiley   +1 more source

Carrot and stick: how RNase R contributes to function and destruction of the translation machinery. [PDF]

RNA Biol
Paternoga H, Dimitrova-Paternoga L.
europepmc   +1 more source

The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma

Chemistry &Biodiversity, EarlyView.
ABSTRACT Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted therapies have improved overall and progression‐free survival rates in metastatic melanoma patients. The effectiveness of these therapies decreases due to multidrug resistance (MDR).
Jacqueline Maphutha, Danielle Twilley, Mona Dawood, Thomas Efferth, Namrita Lall   +4 more
wiley   +1 more source

Complete genome sequences of two <i>Exiguobacterium alkaliphilum</i> isolates from the Brazilian Pantanal hypersaline lakes. [PDF]

Microbiol Resour Announc
Lautert-Dutra W, Dos Santos FM, Pasinato Napp A, Lovato Melo C.   +3 more
europepmc   +1 more source

Transcriptomic and proteomic profiling shows dysregulated immune and metabolic pathways in arrhythmogenic cardiomyopathy

ESC Heart Failure, EarlyView.
Abstract Aims Arrhythmogenic cardiomyopathy (ACM) is a hereditary heart disease characterized by fibrofatty myocardial replacement and a predisposition to malignant ventricular arrhythmias. The underlying pathomechanisms remain incompletely understood, and specific disease markers are sparse.
Deniz Akdis, Lukas Weidmann, Paolo Nanni, Anna Gaertner, Hendrik Milting, Peter Bode, Corinna Brunckhorst, Liang Chen, Felix C. Tanner, Frank Ruschitzka, Ardan M. Saguner, Firat Duru   +11 more
wiley   +1 more source