Results 211 to 220 of about 126,755 (277)

The genetic diversity of tick species in selected areas of Qinghai Province. [PDF]

open access: yesParasitol Res
Chen X   +7 more
europepmc   +1 more source

THE EVOLUTION OF THE TRANSCRIPTION APPARATUS [PDF]

open access: yes, 1985
Gropp, F.   +4 more
core  

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

open access: yesExploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li   +6 more
wiley   +1 more source

Next Generation Sequencing Improves Diagnostic 16S rRNA Amplicon-Based Microbiota Analyses of Clinical Samples Compared to Sanger Sequencing. [PDF]

open access: yesAPMIS
Aftab H   +10 more
europepmc   +1 more source

Modulating Lysine Crotonylation in Ulcerative Colitis Maintains Mitochondrial Homeostasis

open access: yesExploration, EarlyView.
NaCr promotes KCr to impede the inflammatory progression of ulcerative colitis. KCr induces mitophagy by activating the PINK1/PARKIN pathway to restrict NLRP3 inflammasome activation, thereby decreasing the production and release of various inflammatory cytokines, such as IL‐1β and TNF‐α. KCr induces mitophagy and inhibits NLRP3 inflammasome activation
Tongtong Liu   +7 more
wiley   +1 more source

16S Ribosomal RNA Gene PCR and Sequencing for Pediatric Infection Diagnosis, United States, 2020-2023. [PDF]

open access: yesEmerg Infect Dis
Li G   +9 more
europepmc   +1 more source

Lactobacillus helveticus ZJUIDS12 Rescues Alcohol‐Associated Liver Disease via a Clostridium butyricum‐Regulated Intestinal Reg3γ Pathway

open access: yesFood Frontiers, EarlyView.
Lactobacillus helveticus ZJUIDS12 rescues alcohol‐associated liver disease via a Clostridium butyricum‐regulated intestinal Reg3γ pathway. ABSTRACT Alcohol‐associated liver disease (ALD) has become a serious public health issue worldwide. This study was conducted to investigate the protective role of Lactobacillus helveticus ZJUIDS12 (Z12) on ALD. Z12 (
Qinchao Ding   +10 more
wiley   +1 more source

Cardamonin Commands the Colonic Metabolite Columbianetin Acetate to Compete Against LPS in Binding HMGB1 in the Kidney, Preventing Lipopolysaccharide‐Induced Renal Tubular Pyroptosis

open access: yesFood Frontiers, EarlyView.
Cardamonin upregulate sd the intestinal metabolite columbianetin acetate, which competitively bound HMGB1 to prevent LPS‐induced renal tubular cell pyroptosis (the figure is created with BioRender). ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) results in high mortality due to the lack of effective interventions. The current study reports the
Zihui Zhou   +6 more
wiley   +1 more source

Advances in Detecting RNA Modifications Using Direct RNA Nanopore Sequencing

open access: yesAdvanced Genetics, EarlyView.
This review examines recent advances in Oxford Nanopore Technologies direct RNA sequencing, highlighting its expanding capacity to detect RNA modifications beyond m6A. It discusses computational frameworks and basecalling innovations that enable single‐nucleotide and single‐molecule resolution, explores co‐occurring modifications and their regulatory ...
Yaran Liu, Yang Li, Qiang Sun
wiley   +1 more source

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