Results 241 to 250 of about 126,755 (277)

Homoharringtonine suppresses acute myeloid leukemia progression by orchestrating EWSR1 phase separation in an m6A‐YTHDF2‐dependent mechanism

open access: yesiMeta, EarlyView.
Homoharringtonine (HHT), a clinically approved anti‐leukemic drug, directly binds the RNA‐binding protein EWSR1. HHT induces an allosteric conformational switch in the RNA recognition motif of EWSR1, driving self‐association and liquid–liquid phase separation (LLPS). The resulting condensates act as regulatory hubs that sequester the m6A reader YTHDF2,
Ting‐Ting Liu   +17 more
wiley   +1 more source

Lacrimispora sanguinis sp. nov., isolated from human blood. [PDF]

open access: yesPLoS One
Yu HJ   +10 more
europepmc   +1 more source

DNA Barcoding Reveals Cryptic Diversity and Informs Conservation Priorities in Chinese Firmiana Species (Malvaceae) Using Genome Skimming Data DNA条形码揭示中国梧桐属 (锦葵科) 隐存多样性及保护优先级:来自基因组浅层测序数据的证据

open access: yesIntegrative Conservation, EarlyView.
Accurate species identification is critical for conserving endangered Firmiana trees in China. However, morphological similarities among closely related Firmiana species complicate its taxonomic identification. We conducted genome skimming on 62 samples representing all 10 Chinese species and discovered nrITS as the optimal DNA barcode, achieving 100 ...
Li‐Jun Yan   +8 more
wiley   +1 more source

Eutrophication Reshapes Microbial Communities and Life-History Strategies in the Riverine Ecosystems. [PDF]

open access: yesEnviron Microbiol Rep
Li H   +8 more
europepmc   +1 more source

Allometric Scaling in Environmental DNA Concentration of Japanese Eel Anguilla japonica Confirmed Under Laboratory and Natural Conditions 日本鳗 (Anguilla japonica) 环境 DNA 浓度中的异速生长标度在实验室和自然条件下得到证实

open access: yesIntegrative Conservation, EarlyView.
We demonstrated that Anguilla japonica eDNA concentration was allometrically scaled with their body size in both the laboratory and riverine environments. Integrating body size allometry has the potential to improve population abundance estimates in the field, whereas further clarification is required for understanding eDNA production mechanisms ...
Toshiaki S. Jo   +2 more
wiley   +1 more source

Microbiome characterization of a pre-Hispanic man from Zimapán, Mexico: Insights into ancient gut microbial communities. [PDF]

open access: yesPLoS One
Rosas-Plaza S   +6 more
europepmc   +1 more source

Mitochondrial markers (<i>cytochrome c oxidase subunit I</i> and <i>16S ribosomal RNA</i>) as supporting biomarkers for wild bird identification. [PDF]

open access: yesVet World
Marín-Villa J   +5 more
europepmc   +1 more source

Evaluating the Diagnostic Utility of 16S Oxford Nanopore Technology Sequencing in Patients With Central Nervous System Infections and Its Usefulness in Antimicrobial Stewardship. [PDF]

open access: yesJ Infect Dis
Van Dong D   +13 more
europepmc   +1 more source

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