Results 241 to 250 of about 122,430 (279)

From multi‐omics to precision medicine in intracranial aneurysm: Biomarker discovery and multimodal integration

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores intracranial aneurysm biomarker discovery through multi‐omics. It reveals key genes, proteins, and metabolites, and shows how machine‐learning‐based multi‐modal integration may aid diagnosis and treatment. Abstract Despite extensive research, currently, no biomarkers are available for clinical use in intracranial aneurysm (IA ...
Jiaxin Zhang   +4 more
wiley   +1 more source

Expression of De Novo Open Reading Frames in Natural Populations of Drosophila melanogaster

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
We show that newly‐evolved, expressed open reading frames (neORFs) identified in a set of inbred Drosophila melanogaster lines are also expressed in multiple tissues and developmental stages of pooled population samples from Europe and Africa, although differential expression of neORFs between populations is often tissue‐ or stage‐specific. ABSTRACT De
Amanda Glaser‐Schmitt   +4 more
wiley   +1 more source

Calcium butyrate efficacy in pediatric irritable bowel syndrome: Randomized placebo‐controlled multiomics‐based clinical trial

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders, and treatment involves nonpharmacological and pharmacological therapies, even if there is no optimal therapy. This randomized, placebo‐controlled, double‐blind trial aimed to evaluate the efficacy of calcium butyrate supplementation in ...
Fernanda Cristofori   +11 more
wiley   +1 more source

Effects of a high‐fat diet on gut microbiota and possible implications for bone health in male Wistar rats

open access: yesLipids, EarlyView.
Abstract Diet plays an important role in the composition of gut microbiota. Emerging research suggests that bone homeostasis can also be influenced by the gut microbiota. The aim of this study was to assess possible alterations in gut microbiota in an experimental obesity model induced by a high‐fat diet (HFD) and the possible effects on parameters of ...
Fernanda Guedes Rodrigues   +6 more
wiley   +1 more source

The clinical impact of 16S ribosomal RNA PCR and sequencing in the identification of bacterial infections: a 7-year report from a Lebanese tertiary care center. [PDF]

open access: yesFront Cell Infect Microbiol
Youssef N   +14 more
europepmc   +1 more source

Increased gut microbiota diversity in women with uterine fibroids: Insights from a pilot study on gut and reproductive tract microbiota. [PDF]

open access: yesPLoS One
Korczyńska L   +9 more
europepmc   +1 more source

Actinomadura welshii sp. nov., a New Mycetoma Agent in Mexico. [PDF]

open access: yesPLoS Negl Trop Dis
Vera-Cabrera L   +8 more
europepmc   +1 more source

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