Homoharringtonine (HHT), a clinically approved anti‐leukemic drug, directly binds the RNA‐binding protein EWSR1. HHT induces an allosteric conformational switch in the RNA recognition motif of EWSR1, driving self‐association and liquid–liquid phase separation (LLPS). The resulting condensates act as regulatory hubs that sequester the m6A reader YTHDF2,
Ting‐Ting Liu +17 more
wiley +1 more source
Lacrimispora sanguinis sp. nov., isolated from human blood. [PDF]
Yu HJ +10 more
europepmc +1 more source
Accurate species identification is critical for conserving endangered Firmiana trees in China. However, morphological similarities among closely related Firmiana species complicate its taxonomic identification. We conducted genome skimming on 62 samples representing all 10 Chinese species and discovered nrITS as the optimal DNA barcode, achieving 100 ...
Li‐Jun Yan +8 more
wiley +1 more source
Eutrophication Reshapes Microbial Communities and Life-History Strategies in the Riverine Ecosystems. [PDF]
Li H +8 more
europepmc +1 more source
We demonstrated that Anguilla japonica eDNA concentration was allometrically scaled with their body size in both the laboratory and riverine environments. Integrating body size allometry has the potential to improve population abundance estimates in the field, whereas further clarification is required for understanding eDNA production mechanisms ...
Toshiaki S. Jo +2 more
wiley +1 more source
Bacterial diversity in the honey sac during bee foraging on winter-flowering flora and dominant <i>Bacillus subtilis</i> inhibits <i>Hafnia alvei</i>. [PDF]
Wang M, Zhao W, Zhou D, Huang J.
europepmc +1 more source
Microbiome characterization of a pre-Hispanic man from Zimapán, Mexico: Insights into ancient gut microbial communities. [PDF]
Rosas-Plaza S +6 more
europepmc +1 more source
Rhodococcus aromaticivorans sp. nov., an o-xylene degrading bacterium, and evidence supporting reclassification of Rhodococcus jostii RHA1. [PDF]
Muhammad N +4 more
europepmc +1 more source
Mitochondrial markers (<i>cytochrome c oxidase subunit I</i> and <i>16S ribosomal RNA</i>) as supporting biomarkers for wild bird identification. [PDF]
Marín-Villa J +5 more
europepmc +1 more source
Evaluating the Diagnostic Utility of 16S Oxford Nanopore Technology Sequencing in Patients With Central Nervous System Infections and Its Usefulness in Antimicrobial Stewardship. [PDF]
Van Dong D +13 more
europepmc +1 more source

