Results 41 to 50 of about 122,430 (279)

Evidence for diversifying selection of genetic regions of encoding putative collagen-like host-adhesive fibers in Pasteuria penetrans [PDF]

, 2019
© FEMS 2018. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided ...
Anderson, Andrews, Arohi Srivastava, Arslan, Atibalentja, Aziz, Carver, Charles, Cohan, Colson, Davies, Davies, Davies, Davies, Davies, Davies, Degnan, DePristo, Duan, Dutta, Eardly, Espanol, Felsenstein, Filée, Gascuel, Giblin-Davis, Giblin-Davis, Huynen, Jones, Kanehisa, Kaufman, Keith G Davies, Kumar, Legendre, Luijckx, Luijckx, Maddison, Mauchline, McElroy, Metchnikoff, Mohan, Mohan, Mouton, Murtagh, Noel, Philippe, R Developement Core Team, Radó-Trilla, Rajendhran, Romero, Rutherford, Sayre, Sayre, Schouls, Sharad Mohan, Sharma, Stackebrandt, Starr, Steichen, Stirling, Stirling, Sturhan, Sylvestre, Sylvestre, Tamura, Tim H Mauchline, Todd, Wiedenbeck, Woese, Yap, Zilversmit   +70 more
core   +3 more sources

Reading canonical and modified nucleobases in 16S ribosomal RNA using nanopore native RNA sequencing.

PLoS ONE, 2019
The ribosome small subunit is expressed in all living cells. It performs numerous essential functions during translation, including formation of the initiation complex and proofreading of base-pairs between mRNA codons and tRNA anticodons.
Andrew M Smith, Miten Jain, Logan Mulroney, Daniel R Garalde, Mark Akeson   +4 more
doaj   +1 more source

Extensive horizontal gene transfer in cheese-associated bacteria. [PDF]

, 2017
Acquisition of genes through horizontal gene transfer (HGT) allows microbes to rapidly gain new capabilities and adapt to new or changing environments.
Bonham, Kevin S, Dutton, Rachel J, Wolfe, Benjamin E   +2 more
core   +3 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Selection of Peptides Targeting Helix 31 of Bacterial 16S Ribosomal RNA by Screening M13 Phage-Display Libraries

Molecules, 2011
Ribosomal RNA is the catalytic portion of ribosomes, and undergoes a variety of conformational changes during translation. Structural changes in ribosomal RNA can be facilitated by the presence of modified nucleotides. Helix 31 of bacterial 16S ribosomal
Christine S. Chow, Anne-Cécile E. Duc, Philip R. Cunningham, Tek N. Lamichhane, N. Dinuka Abeydeera   +4 more
doaj   +1 more source

Choice of 16S ribosomal RNA primers affects the microbiome analysis in chicken ceca

Scientific Reports, 2021
We evaluated the effect of applying different sets of 16S rRNA primers on bacterial composition, diversity, and predicted function in chicken ceca. Cecal contents from Ross 708 birds at 1, 3, and 5 weeks of age were collected for DNA isolation.
Nadia Darwish, Jonathan Shao, Lori L. Schreier, Monika Proszkowiec-Weglarz   +3 more
doaj   +1 more source

Euglena gracilis chloroplast ribosomal RNA transcription units. II. Nucleotide sequence homology between the 16 S–23 S ribosomal RNA spacer and the 16 S ribosomal RNA leader regions. [PDF]

Journal of Biological Chemistry, 1980
The DNA sequences of two segments of the ribosomal RNA transcription units of Euglena gracilis Pringsheim strain Z chloroplast DNA have been determined. The first is from the 16 S to 23 S rRNA spacer region. The nucleotide sequence determined includes 64 bp from the 3'-end of the 16 S rRNA gene, the adjacent 87-bp spacer containing 68A-T base pairs, a ...
J R Dodd, E M Orozco, Richard B. Hallick, K E Rushlow   +3 more
openaire   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Chromosomal 16S Ribosomal RNA Methyltransferase RmtE1 in Escherichia coli Sequence Type 448

Emerging Infectious Diseases, 2017
We identified rmtE1, an uncommon 16S ribosomal methyltransferase gene, in an aminoglycoside- and cephalosporin-resistant Escherichia coli sequence type 448 clinical strain co-harboring blaCMY-2.
Bin Li, Marissa P. Pacey, Yohei Doi
doaj   +1 more source

The complete mitochondrial genome of Anas penelope (Anatidae: Anas)

Mitochondrial DNA. Part B. Resources, 2020
The complete mitochondrial DNA genome of the Eurasian Wigeon, Anas penelope, was mapped by the next-generation sequencing and Mega 7.0. The circular mitogenome (16,596 bp in length) contains 13 protein-coding genes, 2 rRNA genes (12S ribosomal RNA and ...
Xiaoping Sun, Chaochao Hu, Shuang Li, Mengfan Zhai, Wei Liu, Yinlong Zhang   +5 more
doaj   +1 more source