Results 221 to 230 of about 77,694 (290)

Chemical nucleases are a robust alternative for RNase H cleavage of human ribosomal RNA. [PDF]

PLoS One
Wesseling H, Krug D, Wehrheim M, Göbel MW, Kaiser S.   +4 more
europepmc   +1 more source

Mutations in GFAP Alter Early Lineage Commitment of Organoids

Glia, EarlyView.
Mutations in GFAP alter lineage commitment of organoids. The severity of this commitment defect is dependent on the method of embryoid body formation. GFAP is expressed in iPSCs and during early stages of organoid development. Graphical abstract was created with BioRender.com .
Werner Dykstra, Zuzana Matusova, Rachel A. Battaglia, Pavel Abaffy, Nuria Goya‐Iglesias, Dolores Pérez‐Sala, Henrik Ahlenius, Mikael Kubista, R. Jeroen Pasterkamp, Li Li, Jianfei Chao, Yanhong Shi, Lukas Valihrach, Milos Pekny, Elly M. Hol   +14 more
wiley   +1 more source

METTL5 regulates SEPHS2-mediated selenoprotein synthesis to promote multiple myeloma survival and progression. [PDF]

Cell Death Dis
Jiang J, Zhong F, Xiao Z, Yao F, Liu J, Li M, Zeng H, Qiu Y, Zhang J, Zhang H, Li S, Huang T, Feng W, Huang Z, Huang B, Wang X.   +15 more
europepmc   +1 more source

A comparative analysis of mRNA enrichment strategies and guidance for improving their efficiency. [PDF]

Sci Rep
Andrzejewska-Romanowska A, Tykwińska E, Śledziński P, Pachulska-Wieczorek K.   +3 more
europepmc   +1 more source

Hidden origami in <i>Trypanosoma cruzi</i> nuclei highlights its non-random 3D genomic organization. [PDF]

mBio
Bellini NK, Lima PLCd, Pires DdS, da Cunha JPC.   +3 more
europepmc   +1 more source

The prognostic potential of RNA in stage II colon cancer: Insights from a screened multicenter population‐based cohort study

International Journal of Cancer, EarlyView.
What's New? Patients with stage II colon cancer exhibit considerable variation in prognosis. Consequently, decisions regarding the necessity of adjuvant chemotherapy in this population often rely on imperfect high‐risk criteria. Here, the authors developed a novel RNA‐based risk score, using NanoString nCounter technology, to stratify recurrence risk ...
Ulrik Korsgaard, Maria P. Kristensen, Juan L. García‐Rodríguez, Sanne Kjær‐Frifeldt, Jan Lindebjerg, Torben F. Hansen, Jørgen Kjems, Henrik Hager, Lasse S. Kristensen   +8 more
wiley   +1 more source

Down-regulation of human-specific lncRNA TMEM9B-AS1 in skeletal muscle of people with type 2 diabetes affects ribosomal biogenesis. [PDF]

Sci Adv
Sen I, Smith JAB, Caria E, Orlov I, Savikj M, Brady AJ, Lian K, Ellefsen S, Zierath JR, Krook A.   +9 more
europepmc   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

Structural insights into the recruitment of viral Type 2 IRES to ribosomal preinitiation complex for protein synthesis

Das D, Hussain T.
europepmc   +1 more source

The ribonuclease RNase T2 mediates selective autophagy of ribosomes induced by starvation in Saccharomyces cerevisiae. [PDF]

J Biol Chem
Minami A, Nishi K, Yamada R, Jinnai G, Shima H, Oishi S, Akagawa H, Aono T, Hidaka M, Masaki H, Kuzuyama T, Noda Y, Ogawa T.   +12 more
europepmc   +1 more source