Results 221 to 230 of about 138,758 (334)

The 3'-5' exoribonuclease ISG20L2 contributes to 3' terminus maturation of 18S and 28S ribosomal RNAs. [PDF]

Nucleic Acids Res
Aubert M, Zuber H, Mommert-Tripon M, Page SL, Montel-Lehry N, Soldan V, Bosch S, Gagliardi D, Gleizes PE, O'Donohue MF.   +9 more
europepmc   +1 more source

Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer

Advanced Science, EarlyView.
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo, Yingge Lv, Shuyu Huang, Chang Liu, Yan Ouyang, Bei Lan, Chenghao Xuan   +6 more
wiley   +1 more source

Pathogenetic mechanisms of muscle-specific ribosomes in dilated cardiomyopathy. [PDF]

Nat Cardiovasc Res
Murphy MR, Ganapathi M, Rotlevi ER, Lee TM, Fisher JM, Patel MV, Jayakar P, Buchanan A, Rippert AL, Ahrens-Nicklas RC, Nair D, Nayak SS, Anand A, Shukla A, Soni RK, Yin Y, Yang F, Garcia EJ, Reilly MP, Chung WK, Wu X.   +20 more
europepmc   +1 more source

A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

Advanced Science, EarlyView.
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin, Jovanne Palvair, Lennie Messager, Jamal Bamoulid, Jasper Callemeyn, Mélanie Chaintreuil, Ludivine Dal Zuffo, Didier Ducloux, Imane Farhat, Mathieu Legendre, Laurent Martin, Florian Renosi, Xavier Roussel, Thibaut Vaulet, Maarten Naesens, Claire Tinel, Baptiste Lamarthée   +16 more
wiley   +1 more source

Molecular phylogenies provide insights into the evolutionary relationships of the Spirurida (Nematoda), with special emphasis on the superfamily Physalopteroidea. [PDF]

Parasit Vectors
Sun M, Yousaf MA, Harras S, Gibson DI, Chen HX, Elmahy RA, Li L.   +6 more
europepmc   +1 more source

Tetrapod phylogeny inferred from 18S and 28S ribosomal RNA sequences and a review of the evidence for amniote relationships.

Molecular biology and evolution, 1990
B. Hedges, K. D. Moberg, Linda
semanticscholar   +1 more source

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

Utility of the Ribosomal Gene 18S rRNA in the Classification of the Main House Dust Mites Involved in Hypersensitivity. [PDF]

Int J Mol Sci
García-Dumpierrez A, Rodriguez Gil D, Gallego Segovia MD, Alcover J, Martínez-Gomariz M, Gómez A, Palacios R.   +6 more
europepmc   +1 more source

Depletion of U3 small nucleolar RNA inhibits cleavage in the 5′ external transcribed spacer of yeast pre‐ribosomal RNA and impairs formation of 18S ribosomal RNA.

EMBO Journal, 1991
J. Hughes, M. Ares
semanticscholar   +1 more source

Metarhizium anisopliaeMitigates the Phytotoxicity of Lead and Nanoplastics on Rice by Modifying Physiological, Transcriptomic, Metabolomic Activities, and Soil Microbiome

Advanced Science, EarlyView.
Metarhizium anisopliae alleviates the phytotoxic effects of polyethylene nanoplastics (NP) and lead (Pb) in rice by decreasing Pb uptake, restoring antioxidant and hormonal equilibrium, and promoting growth. Additionally, the fungus modifies the rhizosphere microbiota, enhancing both contaminant tolerance and plant growth, thereby effectively ...
Jing Peng, Qi Yan, Muhammad Umair Hassan, Muhammad Imran, Fasih Ullah Haider, Jianfeng Liang, Xingmin Wang, Shaukat Ali   +7 more
wiley   +1 more source