Results 61 to 70 of about 77,694 (290)

The pathway of hepatitis C virus mRNA recruitment to the human ribosome. [PDF]

, 2009
Eukaryotic protein synthesis begins with mRNA positioning in the ribosomal decoding channel in a process typically controlled by translation-initiation factors.
Doudna, Jennifer A, Fraser, Christopher S, Hershey, John WB   +2 more
core  

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Nucleotide sequence of the 5′-and 3′-domains for rabbit 18S ribosomal RNA [PDF]

Nucleic Acids Research, 1982
By direct RNA sequence analysis we have determined the primary structures of both the 5' and 3' domains for rabbit 18S ribosomal RNA. Purified 18S rRNA was labeled in vitro at either its 5' or 3' terminus with 32P, base-specifically fragmented enzymatically and chemically, and the resulting fragments electrophoretically fractionated by size in adjacent
John F. Connaughton, Ajit Kumar, Raymond E. Lockard   +2 more
openaire   +3 more sources

Three novel science activities relating to the structure of the atom, bioinformatics, and the denaturation of protein [PDF]

, 2013
Plan B Paper. 2013. Master of Science in Education- Physics--University of Wisconsin-River Falls. Physics Department. 30 leaves. Includes bibliographical references (leaf 10).This paper describes three novel activities that were designed to teach ...
Duerst, Robert
core   +1 more source

Monophyly of brachiopods and phoronids: reconciliation of molecular evidence with Linnaean classification (the subphylum Phoroniformea nov.) [PDF]

, 2000
Molecular phylogenetic analyses of aligned 18S rDNA gene sequences from articulate and inarticulate brachiopods representing all major extant lineages, an enhanced set of phoronids and several unrelated protostome taxa, confirm previous indications that ...
Bernard L. Cohen, Emig C. C., Emig C. C., Ka, Winnepenninckx B.   +4 more
core   +2 more sources

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Phylogenetic tree analysis of Entamoeba species isolated from goats

Al-Qadisiyah Journal of Veterinary Medicine Sciences, 2017
The present study was designed to species typing of parasite Entamoeba spp from goats by using PCR technique and phylogenetic tree analysis. The PCR technique was conducted for using specific primers were designed for 18S rRNA gene of Entamoeba spp.
Nuha Qasim Mohammed
doaj  

Variation of expression levels of seven housekeeping genes at different life-history stages in Porphyra yezoensis. [PDF]

PLoS ONE, 2013
In order to identify the optimal internal control for relative real-time PCR when studying target gene expression in the red alga Porphyra yezoensis, we quantified the expression of seven housekeeping genes (18S ribosomal RNA, 30S ribosomal protein S8 ...
Xiaojie Wu, Aiyou Huang, Meiling Xu, Chao Wang, Zhaojun Jia, Guangce Wang, Jianfeng Niu   +6 more
doaj   +1 more source

Conservation of the 5'-Terminal Nucleotide Sequences of Ribosomal 18-S RNA in Eukaryotes. Differential Evolution of Large and Small Ribosomal RNA [PDF]

European Journal of Biochemistry, 1976
The 5'-terminal nucleotide sequences of ribosomal 18-S and 28-S RNA of seven species of eukaryotes including three mammals, one bird, one amphibian, one echinoderm and one slime mold, were analyzed either by means of terminal phosphorylation of RNA with polynucleotide kinase of by fingerprint analysis of uniformly labeled RNA. The following conclusions
Ryo Kominami, Masahiro Sugiura, Masami Muramatsu, Keiko Sakuma   +3 more
openaire   +3 more sources